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The map label for this gene is rlmH

Identifier: 123966251

GI number: 123966251

Start: 910517

End: 910930

Strand: Direct

Name: rlmH

Synonym: P9515_10181

Alternate gene names: 123966251

Gene position: 910517-910930 (Clockwise)

Preceding gene: 123966250

Following gene: 123966252

Centisome position: 53.43

GC content: 28.5

Gene sequence:

>414_bases
ATGCTTAAGGCTAACAGGCTATCAATATATGCTATTGGTAAAATTAAAAAAAAATGGATAAGAGAAGGAATTAATCAATA
CAAAAAAAGAATGCCTGATCTTATTATTAATGAATCCAAGAGTTTTAATATAGATAATATTCGAGTTAATAATATTATTA
TTTGCCTTACTGAAGAAGGTAAATCTTTTAGTTCAACTGAACTAACCTCCTTACTTTTGAATTTTAAAAATAAAAAAATT
AATTTTCTCATTGGAGATGCCGATGGAATTCCTTCAGATATTAAAGACAAATCACATCTTCTACTAAGCCTCTCTCCTCT
TACTTTTCCTCATGAACTTGCAAGATTAATTCTAGTCGAACAAATTTATAGAGTTATTTCTATTTCTAATGGTTCGCCTT
ACCATCGTGCCTAA

Upstream 100 bases:

>100_bases
CAAGAAAACCTAGTTCCTCAAAAAATCTATCTATCGAAGATGAGCTTTATGACGAATTTAATTATCTTCTTGATGAATAG
AGAAATTTTTCTTTTTTTTC

Downstream 100 bases:

>100_bases
AGAGAAAATTTAAAATTATTATATAAAATCTTAAAACAGACACAATTTCAATATTTTAATATATAGTATATATGTACTAT
ATAAAAATGCATTCTTCTGA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEGKSFSSTELTSLLLNFKNKKI
NFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVEQIYRVISISNGSPYHRA

Sequences:

>Translated_137_residues
MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEGKSFSSTELTSLLLNFKNKKI
NFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVEQIYRVISISNGSPYHRA
>Mature_137_residues
MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEGKSFSSTELTSLLLNFKNKKI
NFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVEQIYRVISISNGSPYHRA

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=153, Percent_Identity=28.7581699346405, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_PROM5 (A2BWR4)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011332.1
- ProteinModelPortal:   A2BWR4
- SMR:   A2BWR4
- STRING:   A2BWR4
- GeneID:   4719166
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_10181
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   WIREGIN
- ProtClustDB:   CLSK922031
- BioCyc:   PMAR167542:P9515ORF_1066-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR001936
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 15655; Mature: 15655

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50018 RAS_GTPASE_ACTIV_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEG
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECEEEEEEECCC
KSFSSTELTSLLLNFKNKKINFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVE
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QIYRVISISNGSPYHRA
HHHHHEECCCCCCCCCC
>Mature Secondary Structure
MLKANRLSIYAIGKIKKKWIREGINQYKKRMPDLIINESKSFNIDNIRVNNIIICLTEEG
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECEEEEEEECCC
KSFSSTELTSLLLNFKNKKINFLIGDADGIPSDIKDKSHLLLSLSPLTFPHELARLILVE
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QIYRVISISNGSPYHRA
HHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA