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The map label for this gene is pqqL [C]

Identifier: 123966071

GI number: 123966071

Start: 758900

End: 760147

Strand: Direct

Name: pqqL [C]

Synonym: P9515_08381

Alternate gene names: 123966071

Gene position: 758900-760147 (Clockwise)

Preceding gene: 123966060

Following gene: 123966072

Centisome position: 44.53

GC content: 28.53

Gene sequence:

>1248_bases
ATGAACTTAGGAGAAATTAATTACTATAACCATTCAAGCAAACCTAAATGCGTATTTGTGGAAAATAAAGAATTACCCCT
AATCTGTATAGATTTTTGGTTTAAAGCTGGTTCTTCATTTGAAGAATCAGATAAAAGTGGAACAGCTCATTTGTTAGAAC
ATATGATTTTTAAAGGCAGTAATAAAATAATGCCAGGCGAATTTGATCATAGAATCGAATCTCTGGGTGGAATTAGCAAT
GCTTCAACTGGATATGATGATGCACATTACTATGTTTTAGTACCTAAAAACAACTTTAAAGAGTCACTAGCTCTTTTGAC
AAACATTCTCAGATCACCAAATTTTAATATTAACGAATTTAATAAAGAGAAAAGTGTTGTCATCGATGAAATAAAGCAAC
AAAATGACCAGCCTGATGAAAAGCTTTTTAATTATTTCTTGGGTAGAGTATGGATAGACAACTTTTATGGCAAAACCATA
TTAGGAACTGAAAAGGATGTCCAATCATTAGCAATAGATGATCTAGAAAAATTCCATAAGAAATTTTATAATATCGAGAA
TTCTTGTATCTCGATTGCTGGAAATATCGCAAAAGTAACTTTTGAAGAATGTTACGGAAATAACTTTTCTTATCTTGGTG
AGGCTAACAGTTCTCAAATAATTAGTAAAAATAAATTAATTGCAATCCCAAGAACTGGTAGAGAAGAAATTGATTTTAAG
AATATCGAATTTTCTAGAATATATATGGCATGGAGTATACCCAGCATTAAAAATCAAAGAATAAATATAGGATTTGAAAT
TTTAACTTCGATACTTTCTGTGGGAAGAAATAGTAGATTAGTTAAGGTTTTAAAAGAAGATAAAAATTTGGTTGAGTCAA
TATATGTAGATGTAAATGGAGGAGAATTAGGGGGTTTATTAGTGATTGAAGCTTGCTGCGATAATGTAAATTTATTAAAA
ACTGAGGAAGAAATTAATAAAATAATTAAAGAATTGGTTAGTTCTAAAAATTTAACTATTAATGAGTTGACAAAAGCGTT
AAACATTGTCAAAAGTAACTATATATTTAATCTAGAAACTTCGACACAACTAACTTCATTTTTTGGAAGTGAATTTTTGT
GGGGCAGAAAAAATTCCATAAATGATTTAGATAATCATCTGCGCTACTGGAATAATTTAAATAATTTCAGGAAAATACTA
CATTATCTATCAAAAGATAAATTTACATTAATTGCATCAGCAAAATAA

Upstream 100 bases:

>100_bases
AATAAAGTCAAAATAAGTGGATCAATTAATTTGGTTTTAGTTAAAGATTCAGACAACAAGGGTAAATGGTATCAAAATAA
AGAGTAAGAAAAAAGTTGCG

Downstream 100 bases:

>100_bases
TGAAAAATAGATTTTTTAAAACAAAAACCCAACGAAATTTTTCTGTGGCGATGGTTTGGATAAATGGTGGTAGCAGTGAA
GATAATGAAGGTAAAAAAGG

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNLGEINYYNHSSKPKCVFVENKELPLICIDFWFKAGSSFEESDKSGTAHLLEHMIFKGSNKIMPGEFDHRIESLGGISN
ASTGYDDAHYYVLVPKNNFKESLALLTNILRSPNFNINEFNKEKSVVIDEIKQQNDQPDEKLFNYFLGRVWIDNFYGKTI
LGTEKDVQSLAIDDLEKFHKKFYNIENSCISIAGNIAKVTFEECYGNNFSYLGEANSSQIISKNKLIAIPRTGREEIDFK
NIEFSRIYMAWSIPSIKNQRINIGFEILTSILSVGRNSRLVKVLKEDKNLVESIYVDVNGGELGGLLVIEACCDNVNLLK
TEEEINKIIKELVSSKNLTINELTKALNIVKSNYIFNLETSTQLTSFFGSEFLWGRKNSINDLDNHLRYWNNLNNFRKIL
HYLSKDKFTLIASAK

Sequences:

>Translated_415_residues
MNLGEINYYNHSSKPKCVFVENKELPLICIDFWFKAGSSFEESDKSGTAHLLEHMIFKGSNKIMPGEFDHRIESLGGISN
ASTGYDDAHYYVLVPKNNFKESLALLTNILRSPNFNINEFNKEKSVVIDEIKQQNDQPDEKLFNYFLGRVWIDNFYGKTI
LGTEKDVQSLAIDDLEKFHKKFYNIENSCISIAGNIAKVTFEECYGNNFSYLGEANSSQIISKNKLIAIPRTGREEIDFK
NIEFSRIYMAWSIPSIKNQRINIGFEILTSILSVGRNSRLVKVLKEDKNLVESIYVDVNGGELGGLLVIEACCDNVNLLK
TEEEINKIIKELVSSKNLTINELTKALNIVKSNYIFNLETSTQLTSFFGSEFLWGRKNSINDLDNHLRYWNNLNNFRKIL
HYLSKDKFTLIASAK
>Mature_415_residues
MNLGEINYYNHSSKPKCVFVENKELPLICIDFWFKAGSSFEESDKSGTAHLLEHMIFKGSNKIMPGEFDHRIESLGGISN
ASTGYDDAHYYVLVPKNNFKESLALLTNILRSPNFNINEFNKEKSVVIDEIKQQNDQPDEKLFNYFLGRVWIDNFYGKTI
LGTEKDVQSLAIDDLEKFHKKFYNIENSCISIAGNIAKVTFEECYGNNFSYLGEANSSQIISKNKLIAIPRTGREEIDFK
NIEFSRIYMAWSIPSIKNQRINIGFEILTSILSVGRNSRLVKVLKEDKNLVESIYVDVNGGELGGLLVIEACCDNVNLLK
TEEEINKIIKELVSSKNLTINELTKALNIVKSNYIFNLETSTQLTSFFGSEFLWGRKNSINDLDNHLRYWNNLNNFRKIL
HYLSKDKFTLIASAK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=389, Percent_Identity=22.879177377892, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI46593007, Length=179, Percent_Identity=22.3463687150838, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17553678, Length=371, Percent_Identity=21.2938005390836, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=365, Percent_Identity=23.013698630137, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357875, Length=402, Percent_Identity=22.3880597014925, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24646943, Length=402, Percent_Identity=22.3880597014925, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641429, Length=291, Percent_Identity=25.085910652921, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47511; Mature: 47511

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGEINYYNHSSKPKCVFVENKELPLICIDFWFKAGSSFEESDKSGTAHLLEHMIFKGS
CCCCCEEECCCCCCCCEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHCCC
NKIMPGEFDHRIESLGGISNASTGYDDAHYYVLVPKNNFKESLALLTNILRSPNFNINEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
NKEKSVVIDEIKQQNDQPDEKLFNYFLGRVWIDNFYGKTILGTEKDVQSLAIDDLEKFHK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KFYNIENSCISIAGNIAKVTFEECYGNNFSYLGEANSSQIISKNKLIAIPRTGREEIDFK
HHHCCCHHHHHHCCCHHEEEHHHHCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCC
NIEFSRIYMAWSIPSIKNQRINIGFEILTSILSVGRNSRLVKVLKEDKNLVESIYVDVNG
CCEEEEEEEEEECCCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCC
GELGGLLVIEACCDNVNLLKTEEEINKIIKELVSSKNLTINELTKALNIVKSNYIFNLET
CCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECC
STQLTSFFGSEFLWGRKNSINDLDNHLRYWNNLNNFRKILHYLSKDKFTLIASAK
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MNLGEINYYNHSSKPKCVFVENKELPLICIDFWFKAGSSFEESDKSGTAHLLEHMIFKGS
CCCCCEEECCCCCCCCEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHCCC
NKIMPGEFDHRIESLGGISNASTGYDDAHYYVLVPKNNFKESLALLTNILRSPNFNINEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
NKEKSVVIDEIKQQNDQPDEKLFNYFLGRVWIDNFYGKTILGTEKDVQSLAIDDLEKFHK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KFYNIENSCISIAGNIAKVTFEECYGNNFSYLGEANSSQIISKNKLIAIPRTGREEIDFK
HHHCCCHHHHHHCCCHHEEEHHHHCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCC
NIEFSRIYMAWSIPSIKNQRINIGFEILTSILSVGRNSRLVKVLKEDKNLVESIYVDVNG
CCEEEEEEEEEECCCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCC
GELGGLLVIEACCDNVNLLKTEEEINKIIKELVSSKNLTINELTKALNIVKSNYIFNLET
CCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECC
STQLTSFFGSEFLWGRKNSINDLDNHLRYWNNLNNFRKILHYLSKDKFTLIASAK
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]