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The map label for this gene is pgl [H]

Identifier: 123966047

GI number: 123966047

Start: 731052

End: 731786

Strand: Reverse

Name: pgl [H]

Synonym: P9515_08121

Alternate gene names: 123966047

Gene position: 731786-731052 (Counterclockwise)

Preceding gene: 123966048

Following gene: 123966046

Centisome position: 42.94

GC content: 27.89

Gene sequence:

>735_bases
ATGGATGAAATGATTAAGAAATCTGTTGATGGATACGATTTAAACATATATAAAGATAAATTAGAACTTTCATCTAAAGT
TTCTAAATTTATAGAAAATCAAATTATCCAAACAATAAAGACTAAGGAAAGATTTCAATTTTGTGTAAGTGGGGGTTCAA
CTCCGAAGTCCATTTATCAACTTCTATCAAAAAGGGATATTGAATGGGATAAAGTTGATATTTTTTTAGGTGATGAGAGG
TGTGTTGATCCAAATTCCGAGTTAAGTAACTCTTTTATGTTAAAAAATTCATTGTTAGCAAATTTTGGTTCTAAGGCTTT
TTTCTATGAGATCTTTAGCGAAAAAAAAGTTGATGACAATATCTCTAAAAAATTGTTAATCTCTAAACTATATGAAAAGT
GTAATGGTAATCCTCAATTTTTTGATTTAACTTTATTAGGTCTTGGAGATGATGGCCATACTGCTTCCTTATTTCCTTAT
CAAAATAATAATACTGATGATTTAGTTATTTTTAATGATGGGAAAGGTCTTAAAAGAATTTCTCTAACTCCTAAATTACT
ATCAGCTTCTTCAACAATAATTTTTTTGGTTAGTGGAGCTTCTAAACAATTAGCCCTTAAGAGGTTACTGGATAAAAACG
AATCTCAAGAAAGGACTCCTTCTAAATTAATTAAATCAAGTAACCAGATATCAATATTTTGTGATGAAGAATCTTCAAAA
GAATTATTAACTTAG

Upstream 100 bases:

>100_bases
GAACAAACAGACTTCCACAAAACCTGGTGCAGGCTATGAGAGATTGTTTTGGCTCTCATACTTACGAGAGAATTGATAAA
GAGGGGAGTTTTCATACTGA

Downstream 100 bases:

>100_bases
TTAAAGTCTTTATAGAAACTTTAGTTAATAAATTAATGAGTAAGAAAAAAGTATTATTCCAAAAACAAAAATTTGAAGGA
TGGAAAACCCTAAATGATAC

Product: putative 6-phosphogluconolactonase (DevB, Pgl)

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDEMIKKSVDGYDLNIYKDKLELSSKVSKFIENQIIQTIKTKERFQFCVSGGSTPKSIYQLLSKRDIEWDKVDIFLGDER
CVDPNSELSNSFMLKNSLLANFGSKAFFYEIFSEKKVDDNISKKLLISKLYEKCNGNPQFFDLTLLGLGDDGHTASLFPY
QNNNTDDLVIFNDGKGLKRISLTPKLLSASSTIIFLVSGASKQLALKRLLDKNESQERTPSKLIKSSNQISIFCDEESSK
ELLT

Sequences:

>Translated_244_residues
MDEMIKKSVDGYDLNIYKDKLELSSKVSKFIENQIIQTIKTKERFQFCVSGGSTPKSIYQLLSKRDIEWDKVDIFLGDER
CVDPNSELSNSFMLKNSLLANFGSKAFFYEIFSEKKVDDNISKKLLISKLYEKCNGNPQFFDLTLLGLGDDGHTASLFPY
QNNNTDDLVIFNDGKGLKRISLTPKLLSASSTIIFLVSGASKQLALKRLLDKNESQERTPSKLIKSSNQISIFCDEESSK
ELLT
>Mature_244_residues
MDEMIKKSVDGYDLNIYKDKLELSSKVSKFIENQIIQTIKTKERFQFCVSGGSTPKSIYQLLSKRDIEWDKVDIFLGDER
CVDPNSELSNSFMLKNSLLANFGSKAFFYEIFSEKKVDDNISKKLLISKLYEKCNGNPQFFDLTLLGLGDDGHTASLFPY
QNNNTDDLVIFNDGKGLKRISLTPKLLSASSTIIFLVSGASKQLALKRLLDKNESQERTPSKLIKSSNQISIFCDEESSK
ELLT

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533058, Length=255, Percent_Identity=25.0980392156863, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533060, Length=242, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319918, Length=222, Percent_Identity=30.6306306306306, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324362, Length=218, Percent_Identity=30.2752293577982, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321957, Length=242, Percent_Identity=26.8595041322314, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321687, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 27617; Mature: 27617

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEMIKKSVDGYDLNIYKDKLELSSKVSKFIENQIIQTIKTKERFQFCVSGGSTPKSIYQ
CCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLSKRDIEWDKVDIFLGDERCVDPNSELSNSFMLKNSLLANFGSKAFFYEIFSEKKVDDN
HHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCH
ISKKLLISKLYEKCNGNPQFFDLTLLGLGDDGHTASLFPYQNNNTDDLVIFNDGKGLKRI
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCEEE
SLTPKLLSASSTIIFLVSGASKQLALKRLLDKNESQERTPSKLIKSSNQISIFCDEESSK
ECCHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCC
ELLT
CCCC
>Mature Secondary Structure
MDEMIKKSVDGYDLNIYKDKLELSSKVSKFIENQIIQTIKTKERFQFCVSGGSTPKSIYQ
CCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLSKRDIEWDKVDIFLGDERCVDPNSELSNSFMLKNSLLANFGSKAFFYEIFSEKKVDDN
HHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCH
ISKKLLISKLYEKCNGNPQFFDLTLLGLGDDGHTASLFPYQNNNTDDLVIFNDGKGLKRI
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCEEE
SLTPKLLSASSTIIFLVSGASKQLALKRLLDKNESQERTPSKLIKSSNQISIFCDEESSK
ECCHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCC
ELLT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]