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The map label for this gene is 123966035

Identifier: 123966035

GI number: 123966035

Start: 722197

End: 723264

Strand: Direct

Name: 123966035

Synonym: P9515_08001

Alternate gene names: NA

Gene position: 722197-723264 (Clockwise)

Preceding gene: 123966034

Following gene: 123966036

Centisome position: 42.38

GC content: 38.39

Gene sequence:

>1068_bases
ATGGCATTAAATTACTACAAAAATGAGCTTAAAGAAAATGCTCAACTTTTAGCTTCCAAAGGTAAAGGGATATTAGCTGT
AGATGAATCAACTAAGACAGTAGGTAAAAGATTGGCTGGTATAGGGGTAGAAAATACAGAAGAAAATAGAAAGGCATACA
GAGGAATGCTTTTCACCACTGAAGGTCTTGGCAAGTACATAAGTGGTGCAATTTTATTTGAGGAGACACTTTTCCAGAAC
CATCAAGATGGTGAATCAATGGTTAAAAAGCTAAATGACTTGGGAATAATTCCAGGTATAAAGGTTGATAAAGGTTTAAA
CCCTCTTCCAGGAGGAGGAGATGTAGAAACTTTTTGTTCTGGTTTAGATGGATTAGTAGAAAGAGCGGCGAAATACTACG
AACAAGGCGCAAGATTTGCAAAATGGAGAGCAGTTCTACAAATAACTGAAGATGGTTGTCCTTCAAAATTATCGATACAA
GAAAATGCATGGGGATTAGCCAGATATGCTAGGTCAGTCCAGGAATCAGGATTAGTTCCAATAATTGAACCAGAAATTTT
AATGGATGGTAATCACACTATTGAGAAAACTGCTGAAGTTCAAGAAGAAGTTATTAAGCAGGTATATATTGCTTGTCAGG
CAAATGGAGTTTTCCTTGAGGGAACACTCTTAAAACCTTCGATGACTGTTAATGGAGCTGAGTGCCCGACAAAAGCTGAT
CCTATGAAAGTTGCTGAAATGACAATAAGAACAATGGAAAGATGCGTACCGGCATCAGTTCCTGGAATTGTATTCTTGTC
CGGAGGGTTAAGTGAGGAAGCTGCTTCAGTTTATTTAAACAACATGAATACTCTTTATAGAAAAGCTTTATGGAATGTTT
CGTTCTCTTATGGACGTGCTTTACAGCATTCTTGCTTAAAAGCATGGAAAGGTAGCGAAATAGAGGCTGGGCAAAAGGCT
TTAATTGCAAGAGCTCAGGCAAACTCTGAAGCCTCAACGGGTTCATATGTTGCAGGATCTCAGCCATCATCTGATGAGCA
ATTGTTTGTAGCAGGCTACACATATTAA

Upstream 100 bases:

>100_bases
TAACATTAGTAAGTAACAATTATTACTCGAATAGGTATTGAATTGATTTTATTTTTTCTTCATATTCTGGAAAAATCAAC
TGAACCTAAATTTTTAAAGA

Downstream 100 bases:

>100_bases
AAAGCAGAAAATATACACTTAGACATCTAAATAGTTTCATTAATATTGCACTTAATTTAATTATTAACGTGACATTTGAT
ACCTTCGTATATTAAACTCT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEENRKAYRGMLFTTEGLGKYISGAILFEETLFQN
HQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITEDGCPSKLSIQ
ENAWGLARYARSVQESGLVPIIEPEILMDGNHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGAECPTKAD
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSEIEAGQKA
LIARAQANSEASTGSYVAGSQPSSDEQLFVAGYTY

Sequences:

>Translated_355_residues
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEENRKAYRGMLFTTEGLGKYISGAILFEETLFQN
HQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITEDGCPSKLSIQ
ENAWGLARYARSVQESGLVPIIEPEILMDGNHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGAECPTKAD
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSEIEAGQKA
LIARAQANSEASTGSYVAGSQPSSDEQLFVAGYTY
>Mature_354_residues
ALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEENRKAYRGMLFTTEGLGKYISGAILFEETLFQNH
QDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITEDGCPSKLSIQE
NAWGLARYARSVQESGLVPIIEPEILMDGNHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGAECPTKADP
MKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSEIEAGQKAL
IARAQANSEASTGSYVAGSQPSSDEQLFVAGYTY

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI40354205, Length=354, Percent_Identity=50.2824858757062, Blast_Score=324, Evalue=7e-89,
Organism=Homo sapiens, GI4885063, Length=354, Percent_Identity=48.0225988700565, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI34577112, Length=354, Percent_Identity=47.7401129943503, Blast_Score=302, Evalue=4e-82,
Organism=Homo sapiens, GI34577110, Length=354, Percent_Identity=47.7401129943503, Blast_Score=302, Evalue=4e-82,
Organism=Homo sapiens, GI4557305, Length=354, Percent_Identity=47.7401129943503, Blast_Score=302, Evalue=4e-82,
Organism=Homo sapiens, GI193794814, Length=354, Percent_Identity=47.7401129943503, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI25150450, Length=358, Percent_Identity=47.7653631284916, Blast_Score=306, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI71983985, Length=352, Percent_Identity=48.0113636363636, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI71983990, Length=233, Percent_Identity=49.7854077253219, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI45553577, Length=354, Percent_Identity=50.2824858757062, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI24650282, Length=352, Percent_Identity=50, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI24650280, Length=352, Percent_Identity=50, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI24650278, Length=352, Percent_Identity=50, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI221459619, Length=337, Percent_Identity=50.7418397626113, Blast_Score=307, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24650288, Length=337, Percent_Identity=50.7418397626113, Blast_Score=307, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24650304, Length=348, Percent_Identity=45.4022988505747, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38558; Mature: 38427

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEENRKAYRGMLFTT
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCEEEEE
EGLGKYISGAILFEETLFQNHQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHH
GLDGLVERAAKYYEQGARFAKWRAVLQITEDGCPSKLSIQENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCEECCCHHHHHHHHHHHHHCCCCE
IIEPEILMDGNHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGAECPTKAD
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCCCCCCC
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRA
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LQHSCLKAWKGSEIEAGQKALIARAQANSEASTGSYVAGSQPSSDEQLFVAGYTY
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure 
ALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEENRKAYRGMLFTT
CCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCEEEEE
EGLGKYISGAILFEETLFQNHQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHH
GLDGLVERAAKYYEQGARFAKWRAVLQITEDGCPSKLSIQENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCEECCCHHHHHHHHHHHHHCCCCE
IIEPEILMDGNHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGAECPTKAD
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCCCCCCC
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRA
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LQHSCLKAWKGSEIEAGQKALIARAQANSEASTGSYVAGSQPSSDEQLFVAGYTY
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]