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The map label for this gene is rnhB

Identifier: 123969237

GI number: 123969237

Start: 1449866

End: 1450483

Strand: Direct

Name: rnhB

Synonym: A9601_17051

Alternate gene names: 123969237

Gene position: 1449866-1450483 (Clockwise)

Preceding gene: 123969236

Following gene: 123969239

Centisome position: 86.82

GC content: 30.42

Gene sequence:

>618_bases
ATGCAAGAAAAAAAAGAAGAAGATCTTCAGCAAGCATTGAATAAAGTATCAGAAGTTGGAATAGATGAAGTTGGAAAGGG
AGCAATTTTTGGTCCAGTTTTTGCAGCAGCTGTAGTATTAACAGAAAAAAATAAATTTATCTTAAAACAATTTGGAGTAA
CAGATAGTAAAAAACTAACTCCCAAAAAAAGAAAATTACTTTTACCAAAAATTTTATTACTCTCTTCAGATTATGGAATT
GGGCAATCTTCGGCCAGAGAAATAGATAAGTTAGGTATTAGGGTTGCGACGGAACTTTCAATGATAAGAGCTTTAAGAAA
ATTAAAAGAAAAGCCATCTGAATTAATAATTGATGGCCCCTTATTATTAAGACCATGGAACGGAATTCAGAAAAACATAG
TATCAGGAGATTCAAAGTTTATCTCGATAGCTTCAGCAAGCATAGTTGCCAAAGTTTCACGCGATAATCTAATGGAGAGG
TTAGAAAAAAATTACTCAGGATACTTGATATTTAAAAATAAAGGTTATGGAACCAGAGAGCATCTTTCATTAATCAAAAA
AAATGGAATAACTGAACTTCATAGGAAAAGTTTTTTAAAAAAATCAAAACTTATTTAA

Upstream 100 bases:

>100_bases
GCAAGTTCTAAAGATAAAACTTCAAATAAAACTAATGAAAGTAATGAAGTTGTATCTACAGATAAAAAGGATCAAATTGA
ACTTACAGATGAGCTAAACA

Downstream 100 bases:

>100_bases
TTCACACCATTCTAAAAAATCTTTTACGAGCTGCTGTTGAACCCTTGACTTTATACCCAACAGAATCCCATTTAACACCG
AATGACCAGTAGATTCCAAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQEKKEEDLQQALNKVSEVGIDEVGKGAIFGPVFAAAVVLTEKNKFILKQFGVTDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDKLGIRVATELSMIRALRKLKEKPSELIIDGPLLLRPWNGIQKNIVSGDSKFISIASASIVAKVSRDNLMER
LEKNYSGYLIFKNKGYGTREHLSLIKKNGITELHRKSFLKKSKLI

Sequences:

>Translated_205_residues
MQEKKEEDLQQALNKVSEVGIDEVGKGAIFGPVFAAAVVLTEKNKFILKQFGVTDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDKLGIRVATELSMIRALRKLKEKPSELIIDGPLLLRPWNGIQKNIVSGDSKFISIASASIVAKVSRDNLMER
LEKNYSGYLIFKNKGYGTREHLSLIKKNGITELHRKSFLKKSKLI
>Mature_205_residues
MQEKKEEDLQQALNKVSEVGIDEVGKGAIFGPVFAAAVVLTEKNKFILKQFGVTDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDKLGIRVATELSMIRALRKLKEKPSELIIDGPLLLRPWNGIQKNIVSGDSKFISIASASIVAKVSRDNLMER
LEKNYSGYLIFKNKGYGTREHLSLIKKNGITELHRKSFLKKSKLI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=39.010989010989, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PROMS (A2BT77)

Other databases:

- EMBL:   CP000551
- RefSeq:   YP_001010095.1
- ProteinModelPortal:   A2BT77
- SMR:   A2BT77
- STRING:   A2BT77
- GeneID:   4718436
- GenomeReviews:   CP000551_GR
- KEGG:   pmb:A9601_17051
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK13925
- BioCyc:   PMAR146891:A9601_17051-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22934; Mature: 22934

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKKEEDLQQALNKVSEVGIDEVGKGAIFGPVFAAAVVLTEKNKFILKQFGVTDSKKLT
CCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC
PKKRKLLLPKILLLSSDYGIGQSSAREIDKLGIRVATELSMIRALRKLKEKPSELIIDGP
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
LLLRPWNGIQKNIVSGDSKFISIASASIVAKVSRDNLMERLEKNYSGYLIFKNKGYGTRE
EEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
HLSLIKKNGITELHRKSFLKKSKLI
HHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQEKKEEDLQQALNKVSEVGIDEVGKGAIFGPVFAAAVVLTEKNKFILKQFGVTDSKKLT
CCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC
PKKRKLLLPKILLLSSDYGIGQSSAREIDKLGIRVATELSMIRALRKLKEKPSELIIDGP
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
LLLRPWNGIQKNIVSGDSKFISIASASIVAKVSRDNLMERLEKNYSGYLIFKNKGYGTRE
EEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
HLSLIKKNGITELHRKSFLKKSKLI
HHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA