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The map label for this gene is pheA [H]

Identifier: 123969239

GI number: 123969239

Start: 1451040

End: 1451885

Strand: Direct

Name: pheA [H]

Synonym: A9601_17071

Alternate gene names: 123969239

Gene position: 1451040-1451885 (Clockwise)

Preceding gene: 123969237

Following gene: 123969248

Centisome position: 86.89

GC content: 31.09

Gene sequence:

>846_bases
ATGCCCAAACAAGTTGCATATTTAGGTCCTCAAGGAACATACGCAGAAAAAGCAGCCCATATATTATCAAAGCTTGCCAA
TTTTCATTCACCTATATTTGTACCATGTAACGGGTTACATTCGGTCATTAAATCAATAGCTTATAACAATTGTGATGCTG
CTGTAGTCCCTATAGAAAATTCTGTAGAAGGTGGAGTTACAGCTACTCTAGATGCCCTATGGAAATTTCCTGAAATTTTT
ATAAATAAAGCAATTGTTTTACCTATAAAACATGCATTAATTAGTGATGGAGAACTTTCAAGCATTTCAGAAGTATTATC
TCATCCTCAAGCATTAGCTCAATGTTCAGAATGGTTATCTGAGAATCTTCCAAATGCAATTCCCCTCCCAACAAACTCAA
CATCAGAAGCTGTCAATATGGTAAAAGGGAGTAAATTCAGAGCTGCTATCGGTTCAAAATCAATAATTCAAATCGAAGGA
CTTAAAGAATTAGCCTTTCCTATTAATGATGTTCCAGGTAATTGCACTAGATTTGTTTTATTGAGCAAAGAATCAAATTC
AAATTTAGCTAATATTGCCAGTTTTGCTTTCTCATTAATTTCAAATAAACCTGGCGCTTTGCTTAAAGCTATAAATTATA
TTGCAGATTTTGGATTTAATATGAGTAAAATTGAATCGAGACCTTCAAAAAGAGAATTAGGCGAATACATAATTTATATA
GATGTAGAAATCAATAATCAAAAAAATATAAAAAGTTTTCTTGAGTTAAAAAATAAAATAAAGCCGCTTTGTAAGAATTT
TGTTGATTTTGGAAATTATTTTTCTGAAAATGTTGAACTAGATTAA

Upstream 100 bases:

>100_bases
TGTTACAGAAAGCTTAAGTTTCTGTTTAGCATCAAAAGACAATAGCATTTTCTATATTCCTCCAATGCTTATTTGATCTC
TTTTTTTTTTACGATTAATC

Downstream 100 bases:

>100_bases
CTTATCCTCTACATTTATAAACTCCAAACTCCATTAAACCTTTTCTAAATGCCCAATTCATGAGAAGTATTGTTGGTATT
TCTCTAATCGACTTCACTAT

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPKQVAYLGPQGTYAEKAAHILSKLANFHSPIFVPCNGLHSVIKSIAYNNCDAAVVPIENSVEGGVTATLDALWKFPEIF
INKAIVLPIKHALISDGELSSISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSIIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
DVEINNQKNIKSFLELKNKIKPLCKNFVDFGNYFSENVELD

Sequences:

>Translated_281_residues
MPKQVAYLGPQGTYAEKAAHILSKLANFHSPIFVPCNGLHSVIKSIAYNNCDAAVVPIENSVEGGVTATLDALWKFPEIF
INKAIVLPIKHALISDGELSSISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSIIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
DVEINNQKNIKSFLELKNKIKPLCKNFVDFGNYFSENVELD
>Mature_280_residues
PKQVAYLGPQGTYAEKAAHILSKLANFHSPIFVPCNGLHSVIKSIAYNNCDAAVVPIENSVEGGVTATLDALWKFPEIFI
NKAIVLPIKHALISDGELSSISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSIIQIEGL
KELAFPINDVPGNCTRFVLLSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYID
VEINNQKNIKSFLELKNKIKPLCKNFVDFGNYFSENVELD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=289, Percent_Identity=30.7958477508651, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324013, Length=316, Percent_Identity=27.5316455696203, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30760; Mature: 30628

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQVAYLGPQGTYAEKAAHILSKLANFHSPIFVPCNGLHSVIKSIAYNNCDAAVVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCCCEEEEECCC
SVEGGVTATLDALWKFPEIFINKAIVLPIKHALISDGELSSISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSIIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
EECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DVEINNQKNIKSFLELKNKIKPLCKNFVDFGNYFSENVELD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PKQVAYLGPQGTYAEKAAHILSKLANFHSPIFVPCNGLHSVIKSIAYNNCDAAVVPIEN
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCCCEEEEECCC
SVEGGVTATLDALWKFPEIFINKAIVLPIKHALISDGELSSISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSKFRAAIGSKSIIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNLANIASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYI
EECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DVEINNQKNIKSFLELKNKIKPLCKNFVDFGNYFSENVELD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]