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The map label for this gene is mcpA [H]

Identifier: 121998938

GI number: 121998938

Start: 2371281

End: 2372525

Strand: Reverse

Name: mcpA [H]

Synonym: Hhal_2159

Alternate gene names: 121998938

Gene position: 2372525-2371281 (Counterclockwise)

Preceding gene: 121998939

Following gene: 121998937

Centisome position: 88.58

GC content: 64.82

Gene sequence:

>1245_bases
ATGGTCGAGGTTGCCGAGGATCGCGACGGCGAGTCCATCGTCTACCACCCGAAGACGGCGTGGCTGCGCCACTATGGTGC
CCCGTCGGTGTTGACCGCGGTGGCGATGGCGATCGCCTACGCCTGGCCGGCGACAGGACCGCTGGCGGTGGTGCTCGGCG
CCAGCGGTTGGGCCGCGGTCGGCTATCTGCGCCGACGCGAGACGGGGTGGAACGAGGCGACGGATACCGTGGAGGATCTG
GAAGACGCCCTGCGCGATCTGCTCCACGACATCGACGATAGTCTCAACGCCGAGTTCCGTACGGTGAACAGTGACCTGGA
GCAGATCCGCGGGCTCGTCGGCGACGCCGTGCAGTCGCTCAATCAGAGCTTCAACGGCATGGATCAGGCCACGGATGAAC
AGGAACGCCTGGCTCGGGCGGTGATCGAGCAGACCGGCGGGGATTCGGCCGTGGAACAGTTCGGCATCGCCGAGTTCGTC
CACGAGACCGAATCCTTCCTGAACAACTACGTCGAGATGGTCGTCGACATGAGTCGGCGCAGCGTGAAGACCGTCGAGCG
CATCGACGATATGGTCCACCAGATGGACCGGATCCACAAGCTGCTCGCCGACCTCAAAGGGATCGCCAGCCAGACTGACC
TGCTCGCTCTCAATGCCAGCATCGAGGCGGCCCGCGCCGGTGAGTCCGGCCGCGGTTTCGCGGTGGTGGCCGAGGAGGTC
CGCAAGCTCTCCGAGAAGGCCAACCAGTTCAACGAGCAGATCGCTCAGGAGGTCAAGACCATCAGTAACCTGGTGGACGA
GGCGCGCACCGAGGTCGGCGAGATGGCCTCCAACGACATGAACGTGACCCTCACCACCAAGGAGCAGATCTCGGGGATGA
TGAAGAGTCTCCAGGACGTGGATCAGCAGGTGGAGCAGCAGGTCAAGCGCATCTCTGAGGTCAGTGGACAGATCGATCAC
CACGTGGCCGACGCCGTTCGTGCCCTGCAGTTCGAGGACATTGTGACGCAGTTGGTGGATGGCTCGCGCGCCGGGGTCGA
GGGTTTGGATGACTACCTCGATGGCGTGCGCAATGTCCTGCAGGCCATCGCCGAGGAGGACGTCCACGGCAGCCAGTACG
CGGCGCGTCTACGCGAGGCCCGCGAGCGGCTGGCGCAGCAGCGTCAGGAGCGCGAGACGGCGCGGGCCAGCCAGCGCAAG
GTGGAGCAACACTCCATGGATCACGGCGACGTGGAGCTATTCTGA

Upstream 100 bases:

>100_bases
AGGCCGGCCACGCGGACCAGGTCCTGCCGCTGGAGCGGATCGCCGAGGCGATCCAGGCGGCGGTGGCGCCGCCCTCCCAA
CCCACCCAGGAGAGGTGAAT

Downstream 100 bases:

>100_bases
TCGCCGTCGTCGTGGCGCACGCGGGCCTTGGGGCGGGGCGCGTCGGCGGCAGTGGCCTGCCGCCGGTATTCGAGCGTAAT
CATCGCTCAACAGTCAGTCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MVEVAEDRDGESIVYHPKTAWLRHYGAPSVLTAVAMAIAYAWPATGPLAVVLGASGWAAVGYLRRRETGWNEATDTVEDL
EDALRDLLHDIDDSLNAEFRTVNSDLEQIRGLVGDAVQSLNQSFNGMDQATDEQERLARAVIEQTGGDSAVEQFGIAEFV
HETESFLNNYVEMVVDMSRRSVKTVERIDDMVHQMDRIHKLLADLKGIASQTDLLALNASIEAARAGESGRGFAVVAEEV
RKLSEKANQFNEQIAQEVKTISNLVDEARTEVGEMASNDMNVTLTTKEQISGMMKSLQDVDQQVEQQVKRISEVSGQIDH
HVADAVRALQFEDIVTQLVDGSRAGVEGLDDYLDGVRNVLQAIAEEDVHGSQYAARLREARERLAQQRQERETARASQRK
VEQHSMDHGDVELF

Sequences:

>Translated_414_residues
MVEVAEDRDGESIVYHPKTAWLRHYGAPSVLTAVAMAIAYAWPATGPLAVVLGASGWAAVGYLRRRETGWNEATDTVEDL
EDALRDLLHDIDDSLNAEFRTVNSDLEQIRGLVGDAVQSLNQSFNGMDQATDEQERLARAVIEQTGGDSAVEQFGIAEFV
HETESFLNNYVEMVVDMSRRSVKTVERIDDMVHQMDRIHKLLADLKGIASQTDLLALNASIEAARAGESGRGFAVVAEEV
RKLSEKANQFNEQIAQEVKTISNLVDEARTEVGEMASNDMNVTLTTKEQISGMMKSLQDVDQQVEQQVKRISEVSGQIDH
HVADAVRALQFEDIVTQLVDGSRAGVEGLDDYLDGVRNVLQAIAEEDVHGSQYAARLREARERLAQQRQERETARASQRK
VEQHSMDHGDVELF
>Mature_414_residues
MVEVAEDRDGESIVYHPKTAWLRHYGAPSVLTAVAMAIAYAWPATGPLAVVLGASGWAAVGYLRRRETGWNEATDTVEDL
EDALRDLLHDIDDSLNAEFRTVNSDLEQIRGLVGDAVQSLNQSFNGMDQATDEQERLARAVIEQTGGDSAVEQFGIAEFV
HETESFLNNYVEMVVDMSRRSVKTVERIDDMVHQMDRIHKLLADLKGIASQTDLLALNASIEAARAGESGRGFAVVAEEV
RKLSEKANQFNEQIAQEVKTISNLVDEARTEVGEMASNDMNVTLTTKEQISGMMKSLQDVDQQVEQQVKRISEVSGQIDH
HVADAVRALQFEDIVTQLVDGSRAGVEGLDDYLDGVRNVLQAIAEEDVHGSQYAARLREARERLAQQRQERETARASQRK
VEQHSMDHGDVELF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=147, Percent_Identity=31.2925170068027, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI2367378, Length=110, Percent_Identity=40, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789453, Length=174, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787690, Length=123, Percent_Identity=36.5853658536585, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788195, Length=113, Percent_Identity=39.8230088495575, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 45933; Mature: 45933

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEVAEDRDGESIVYHPKTAWLRHYGAPSVLTAVAMAIAYAWPATGPLAVVLGASGWAAV
CCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
GYLRRRETGWNEATDTVEDLEDALRDLLHDIDDSLNAEFRTVNSDLEQIRGLVGDAVQSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NQSFNGMDQATDEQERLARAVIEQTGGDSAVEQFGIAEFVHETESFLNNYVEMVVDMSRR
HHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKTVERIDDMVHQMDRIHKLLADLKGIASQTDLLALNASIEAARAGESGRGFAVVAEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCHHHHHCCCCCCCHHHHHHHH
RKLSEKANQFNEQIAQEVKTISNLVDEARTEVGEMASNDMNVTLTTKEQISGMMKSLQDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
DQQVEQQVKRISEVSGQIDHHVADAVRALQFEDIVTQLVDGSRAGVEGLDDYLDGVRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QAIAEEDVHGSQYAARLREARERLAQQRQERETARASQRKVEQHSMDHGDVELF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVEVAEDRDGESIVYHPKTAWLRHYGAPSVLTAVAMAIAYAWPATGPLAVVLGASGWAAV
CCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHH
GYLRRRETGWNEATDTVEDLEDALRDLLHDIDDSLNAEFRTVNSDLEQIRGLVGDAVQSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NQSFNGMDQATDEQERLARAVIEQTGGDSAVEQFGIAEFVHETESFLNNYVEMVVDMSRR
HHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKTVERIDDMVHQMDRIHKLLADLKGIASQTDLLALNASIEAARAGESGRGFAVVAEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCHHHHHCCCCCCCHHHHHHHH
RKLSEKANQFNEQIAQEVKTISNLVDEARTEVGEMASNDMNVTLTTKEQISGMMKSLQDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
DQQVEQQVKRISEVSGQIDHHVADAVRALQFEDIVTQLVDGSRAGVEGLDDYLDGVRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QAIAEEDVHGSQYAARLREARERLAQQRQERETARASQRKVEQHSMDHGDVELF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]