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The map label for this gene is cheB1 [H]

Identifier: 121998939

GI number: 121998939

Start: 2372528

End: 2373577

Strand: Reverse

Name: cheB1 [H]

Synonym: Hhal_2160

Alternate gene names: 121998939

Gene position: 2373577-2372528 (Counterclockwise)

Preceding gene: 121998940

Following gene: 121998938

Centisome position: 88.62

GC content: 69.71

Gene sequence:

>1050_bases
ATGATCCGGGTCCTGATTGTCGACGACTCCGCGCTGATCCGGCGGCTGCTGGCCGAGCTGTTCGCAGCGGAAGAGGGCAT
CGAGGTTGTGGGGACGGCCCGGGACCCCTACGACGCCCGTGAGAAGATCAAGCAGCTCAATCCCGATGTCCTGACCCTCG
ACGTCGAGATGCCGCGCATGGACGGCATCACCTTCCTGCGCAATCTGATGCGGCTGCGCCCCATGCCGGTGGTCATGGTC
TCTTCGCTGACCGAGGTCGGCGCCGAGGAGACCCTGGAGGCGCTCGCGCTGGGCGCCGTGGACTTCGTCACCAAGCCGAA
AGCCGATGTCAGCTATGCGCTGGAGGGGTATCGGGACGAGATCGTGGCCAAGGTGCGCGCCGCGGCGCAGGCGCGGGTCC
GGCCCGGCCCCGCACGAAGCGCGGCCGCAGCCCCGCCTCGCCCCCACCAGCGCACCACAGATAAGGTCGTGGCCATCGGC
GCCTCCACCGGTGGCACCGTGGCGGTGCAGCGGCTGCTCGAAGTGATGCCGCCCAACGCGCCGGCCACGGTGATCACCCA
GCACATGCCGCCGGGGTTCTCGGCGGCCTTCGCCCAGCGGCTCGATCACCTCTGCGCGGTCTCGGTACACGAGGCGCAGG
ACGGACAGCGGGTGTTGCCCGGGCACGTCTACATCGCGCCCGGCGGGTACCACCTGGAGTTGCACCGGGACGGTAGCAAG
TACATTTGCCGGGTCACGGAGGGGGAACTGGTCAACCGCCACCGGCCTTCCGTAGATGTGCTGTTCAACTCGGTGGCCAC
CTCGGCCCGTGCTAACGCCGTGGGCGTGCTGCTCACCGGCATGGGCAGCGACGGAGCCGTTGGCTTGGGGCGCATGCAGG
CAGCGGGAGCGGTTACCATCGCCCAGGATGAGGCGAGCAGTGTCGTATGGGGGATGCCGGGCGCTGCCGTCAAGGCCGGC
CACGCGGACCAGGTCCTGCCGCTGGAGCGGATCGCCGAGGCGATCCAGGCGGCGGTGGCGCCGCCCTCCCAACCCACCCA
GGAGAGGTGA

Upstream 100 bases:

>100_bases
GCAACGACACCGTCGTGCGCCGCGAGGAGCACTACCTCCACGAGATCGACGAGCAGCCGGTCTCCGGCGACGTCGACCTG
TTTTGAGGACGCAGCGCGGT

Downstream 100 bases:

>100_bases
ATATGGTCGAGGTTGCCGAGGATCGCGACGGCGAGTCCATCGTCTACCACCCGAAGACGGCGTGGCTGCGCCACTATGGT
GCCCCGTCGGTGTTGACCGC

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MIRVLIVDDSALIRRLLAELFAAEEGIEVVGTARDPYDAREKIKQLNPDVLTLDVEMPRMDGITFLRNLMRLRPMPVVMV
SSLTEVGAEETLEALALGAVDFVTKPKADVSYALEGYRDEIVAKVRAAAQARVRPGPARSAAAAPPRPHQRTTDKVVAIG
ASTGGTVAVQRLLEVMPPNAPATVITQHMPPGFSAAFAQRLDHLCAVSVHEAQDGQRVLPGHVYIAPGGYHLELHRDGSK
YICRVTEGELVNRHRPSVDVLFNSVATSARANAVGVLLTGMGSDGAVGLGRMQAAGAVTIAQDEASSVVWGMPGAAVKAG
HADQVLPLERIAEAIQAAVAPPSQPTQER

Sequences:

>Translated_349_residues
MIRVLIVDDSALIRRLLAELFAAEEGIEVVGTARDPYDAREKIKQLNPDVLTLDVEMPRMDGITFLRNLMRLRPMPVVMV
SSLTEVGAEETLEALALGAVDFVTKPKADVSYALEGYRDEIVAKVRAAAQARVRPGPARSAAAAPPRPHQRTTDKVVAIG
ASTGGTVAVQRLLEVMPPNAPATVITQHMPPGFSAAFAQRLDHLCAVSVHEAQDGQRVLPGHVYIAPGGYHLELHRDGSK
YICRVTEGELVNRHRPSVDVLFNSVATSARANAVGVLLTGMGSDGAVGLGRMQAAGAVTIAQDEASSVVWGMPGAAVKAG
HADQVLPLERIAEAIQAAVAPPSQPTQER
>Mature_349_residues
MIRVLIVDDSALIRRLLAELFAAEEGIEVVGTARDPYDAREKIKQLNPDVLTLDVEMPRMDGITFLRNLMRLRPMPVVMV
SSLTEVGAEETLEALALGAVDFVTKPKADVSYALEGYRDEIVAKVRAAAQARVRPGPARSAAAAPPRPHQRTTDKVVAIG
ASTGGTVAVQRLLEVMPPNAPATVITQHMPPGFSAAFAQRLDHLCAVSVHEAQDGQRVLPGHVYIAPGGYHLELHRDGSK
YICRVTEGELVNRHRPSVDVLFNSVATSARANAVGVLLTGMGSDGAVGLGRMQAAGAVTIAQDEASSVVWGMPGAAVKAG
HADQVLPLERIAEAIQAAVAPPSQPTQER

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=342, Percent_Identity=54.3859649122807, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=38.0952380952381, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37078; Mature: 37078

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIVDDSALIRRLLAELFAAEEGIEVVGTARDPYDAREKIKQLNPDVLTLDVEMPRM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
DGITFLRNLMRLRPMPVVMVSSLTEVGAEETLEALALGAVDFVTKPKADVSYALEGYRDE
CCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IVAKVRAAAQARVRPGPARSAAAAPPRPHQRTTDKVVAIGASTGGTVAVQRLLEVMPPNA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
PATVITQHMPPGFSAAFAQRLDHLCAVSVHEAQDGQRVLPGHVYIAPGGYHLELHRDGSK
CCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCEECCCEEEEECCCEEEEEEECCCE
YICRVTEGELVNRHRPSVDVLFNSVATSARANAVGVLLTGMGSDGAVGLGRMQAAGAVTI
EEEEECCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCEEEE
AQDEASSVVWGMPGAAVKAGHADQVLPLERIAEAIQAAVAPPSQPTQER
ECCCCCCEEECCCCHHEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIRVLIVDDSALIRRLLAELFAAEEGIEVVGTARDPYDAREKIKQLNPDVLTLDVEMPRM
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
DGITFLRNLMRLRPMPVVMVSSLTEVGAEETLEALALGAVDFVTKPKADVSYALEGYRDE
CCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IVAKVRAAAQARVRPGPARSAAAAPPRPHQRTTDKVVAIGASTGGTVAVQRLLEVMPPNA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
PATVITQHMPPGFSAAFAQRLDHLCAVSVHEAQDGQRVLPGHVYIAPGGYHLELHRDGSK
CCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCEECCCEEEEECCCEEEEEEECCCE
YICRVTEGELVNRHRPSVDVLFNSVATSARANAVGVLLTGMGSDGAVGLGRMQAAGAVTI
EEEEECCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCEEEE
AQDEASSVVWGMPGAAVKAGHADQVLPLERIAEAIQAAVAPPSQPTQER
ECCCCCCEEECCCCHHEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]