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The map label for this gene is mlaD [H]

Identifier: 121998897

GI number: 121998897

Start: 2321723

End: 2322178

Strand: Reverse

Name: mlaD [H]

Synonym: Hhal_2118

Alternate gene names: 121998897

Gene position: 2322178-2321723 (Counterclockwise)

Preceding gene: 121998898

Following gene: 121998896

Centisome position: 86.7

GC content: 68.2

Gene sequence:

>456_bases
ATGAGTCAGCGGCTCGTGGAGATCTGGGTCGGGGTGTTCGTGGCCATTGGCCTGGCGGCGATGATGGTCCTGGCCCTGCA
GGTCAGTGGCCTGACCGAGCTGCGCCAGCCGCCCGGGTACTACGTCACGGCCAAGTTCGACAATGTCGGCGGCCTGCGCG
AGAAGGCGCCGGTGAGCATGGCCGGGGTCCGGGTCGGACGGGTTGAGGAGATCCGGCTCGATCCGGAGAGCCATCAGGCC
GAGGTGCGGCTGCGCATTAACGAGCGCTTCGGGGCCATCCCGGCAGACAGCGCGGCGGCCATCTACACCGCCGGTCTGCT
CGGCGAGCAGTACGTGGGGCTGGAGCCAGGCTGGGAGACCGAGCCCCTGAGTGACGGCGACCGGATCACCGAGACCCAGT
CGGCGGTGGTCCTGGAGCGGATCATCGGGCAGTTCGTCACCAGCATGCAGGATTGA

Upstream 100 bases:

>100_bases
CAGTCGGGCGACGACCTTGGGCGTCGTGCACGCTTCGCTGGCGGTGCTCGGGCTCGACTTCCTGCTCACCGCACTGATGT
TCGACTGACGGAGCAAGGGT

Downstream 100 bases:

>100_bases
GCTCGCCACGCGCGACGGAGGCAGTAGAGATGTTCAAGGTGAATCGCTGGACTCGTTCACTGGCCGTGTCGATGGCCCTG
TTGCTGGCGCTGGCCTTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSQRLVEIWVGVFVAIGLAAMMVLALQVSGLTELRQPPGYYVTAKFDNVGGLREKAPVSMAGVRVGRVEEIRLDPESHQA
EVRLRINERFGAIPADSAAAIYTAGLLGEQYVGLEPGWETEPLSDGDRITETQSAVVLERIIGQFVTSMQD

Sequences:

>Translated_151_residues
MSQRLVEIWVGVFVAIGLAAMMVLALQVSGLTELRQPPGYYVTAKFDNVGGLREKAPVSMAGVRVGRVEEIRLDPESHQA
EVRLRINERFGAIPADSAAAIYTAGLLGEQYVGLEPGWETEPLSDGDRITETQSAVVLERIIGQFVTSMQD
>Mature_150_residues
SQRLVEIWVGVFVAIGLAAMMVLALQVSGLTELRQPPGYYVTAKFDNVGGLREKAPVSMAGVRVGRVEEIRLDPESHQAE
VRLRINERFGAIPADSAAAIYTAGLLGEQYVGLEPGWETEPLSDGDRITETQSAVVLERIIGQFVTSMQD

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG1463

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaD family [H]

Homologues:

Organism=Escherichia coli, GI1789584, Length=151, Percent_Identity=45.6953642384106, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003399 [H]

Pfam domain/function: PF02470 MCE [H]

EC number: NA

Molecular weight: Translated: 16445; Mature: 16314

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRLVEIWVGVFVAIGLAAMMVLALQVSGLTELRQPPGYYVTAKFDNVGGLREKAPVSM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCCCCCCCCCCCHH
AGVRVGRVEEIRLDPESHQAEVRLRINERFGAIPADSAAAIYTAGLLGEQYVGLEPGWET
HCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
EPLSDGDRITETQSAVVLERIIGQFVTSMQD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQRLVEIWVGVFVAIGLAAMMVLALQVSGLTELRQPPGYYVTAKFDNVGGLREKAPVSM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCCCCCCCCCCCHH
AGVRVGRVEEIRLDPESHQAEVRLRINERFGAIPADSAAAIYTAGLLGEQYVGLEPGWET
HCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
EPLSDGDRITETQSAVVLERIIGQFVTSMQD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]