Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 121998873

GI number: 121998873

Start: 2298800

End: 2299882

Strand: Reverse

Name: mraY

Synonym: Hhal_2094

Alternate gene names: 121998873

Gene position: 2299882-2298800 (Counterclockwise)

Preceding gene: 121998874

Following gene: 121998872

Centisome position: 85.87

GC content: 65.37

Gene sequence:

>1083_bases
GTGCTCTACCACTTGGCCATGGTACTGGAGACGTTCTACTCCGGGTTCAACGTCTTCCAGTACATCACGTTCCGGACCAT
CCTCGGGGTGCTGACCGCCCTGGGGATCGCGCTGATGATCGGCCCTGCGGTGATCCAGCGTCTGGTGCTCCACCAAGTGG
GGCAGCAGGTCCGGGACGACGGCCCGGAGACGCACCTGGAGAAGGCCGGTACCCCGACCATGGGCGGCGCGCTGATCCTC
GTTGCCATCGCGGTTTCCACGCTGCTTTGGGCGGATCTGACCAACCGCTACGTCTGGGTGGTCCTGCTGGTCACGCTCGC
CTTCGGGCTCATCGGCGGGGTCGACGATGCCCTCAAGCTGGCCCGTCAGGACAGCCAGGGCCTGCGTGCCCGGACCAAGT
TCTCGCTGCAGGTGTTGGCGGCGCTGGCGGCGAGCACCTTCCTGTTTGCCACTGCCACGGATCCGGTGGAGACCAGCCTG
GTGCTGCCCCTGGTCAAGGAGTGGGTCTTCCCGCTGGGCCTCGGTTTCATCGCCCTGGCGACGCTGGTGATCGTGGGTAG
TTCCAATGCCGTGAACCTGACCGACGGGCTGGATGGACTGGCGATCATGCCCACGGTGCTGGTGGCCACCGGGCTGGCGG
TCTTCGCCTACGCTAGCGGGCACCACGTCTTTGCCGATTACCTCGGTATCCCGTCGGTGCCCGGGGTGGGCGAGCTGGTG
ATCTTCTGTGGCGCCATCGTCGGTGCTGGGCTCGGGTTCCTCTGGTACAACACCTACCCCGCGCAGGTCTTCATGGGCGA
CGTGGGGGCCCTGGCCCTTGGGGCCGCGCTGGGCGTGGTGGCCGTGGCCGTCCGTCAGGAGATCGTGCTCTTCATCATGG
GCGGGATCTTCGTCATGGAGACGGTCTCGGTGATGATCCAGGTCCTCTCCTACAAACTCACCGGGCGCCGGGTCTTTCGC
ATGGCGCCGTTGCACCACCACTACGAACTCAAGGGTTGGCCGGAGCCGCGGGTGATTGTCCGTTTCTGGATCATCACCGT
GGTCCTGGTTCTGATCGGTCTGGCGATGTTGAAGGTGCGCTGA

Upstream 100 bases:

>100_bases
TGCGGTCGTGCTGATCAAGGGGTCGCGCTCAGCCGCCATGGAGCGCGTGGCGGCGGGCCTGACCTGCACCGAACCAACAA
GAGAAGGGGAGGGACGCTAG

Downstream 100 bases:

>100_bases
TGACGGCAAGCGACCGCCAGCAAGGGTACACCGCTGTCGCCGGTCTCGGGGCGACGGGGATGGCCTGTGTGCGCCATCTG
CGCGCCCGTGGTGTCGTGGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDDGPETHLEKAGTPTMGGALIL
VAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKLARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSL
VLPLVKEWVFPLGLGFIALATLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELV
IFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVMETVSVMIQVLSYKLTGRRVFR
MAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR

Sequences:

>Translated_360_residues
MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDDGPETHLEKAGTPTMGGALIL
VAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKLARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSL
VLPLVKEWVFPLGLGFIALATLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELV
IFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVMETVSVMIQVLSYKLTGRRVFR
MAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR
>Mature_360_residues
MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDDGPETHLEKAGTPTMGGALIL
VAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKLARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSL
VLPLVKEWVFPLGLGFIALATLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELV
IFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVMETVSVMIQVLSYKLTGRRVFR
MAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=61.3888888888889, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_HALHL (A1WYU6)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003660.1
- STRING:   A1WYU6
- GeneID:   4709972
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2094
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   A1WYU6
- ProtClustDB:   PRK00108
- BioCyc:   HHAL349124:HHAL_2094-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38646; Mature: 38646

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c13c360)-; HASH(0x1c248804)-; HASH(0x1c23f270)-; HASH(0x1c23b940)-; HASH(0x1c23f174)-; HASH(0x1c22e048)-; HASH(0x1c240be4)-; HASH(0x1be3135c)-; HASH(0x1c23f2b8)-; HASH(0x1c248474)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPETHLEKAGTPTMGGALILVAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKL
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSLVLPLVKEWVFPLGLGFIALA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELV
HHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHH
IFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVME
HHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVMIQVLSYKLTGRRVFRMAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLYHLAMVLETFYSGFNVFQYITFRTILGVLTALGIALMIGPAVIQRLVLHQVGQQVRDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPETHLEKAGTPTMGGALILVAIAVSTLLWADLTNRYVWVVLLVTLAFGLIGGVDDALKL
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ARQDSQGLRARTKFSLQVLAALAASTFLFATATDPVETSLVLPLVKEWVFPLGLGFIALA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLVIVGSSNAVNLTDGLDGLAIMPTVLVATGLAVFAYASGHHVFADYLGIPSVPGVGELV
HHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHH
IFCGAIVGAGLGFLWYNTYPAQVFMGDVGALALGAALGVVAVAVRQEIVLFIMGGIFVME
HHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVMIQVLSYKLTGRRVFRMAPLHHHYELKGWPEPRVIVRFWIITVVLVLIGLAMLKVR
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA