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The map label for this gene is ftsW [H]

Identifier: 121998871

GI number: 121998871

Start: 2296277

End: 2297464

Strand: Reverse

Name: ftsW [H]

Synonym: Hhal_2092

Alternate gene names: 121998871

Gene position: 2297464-2296277 (Counterclockwise)

Preceding gene: 121998872

Following gene: 121998870

Centisome position: 85.78

GC content: 70.2

Gene sequence:

>1188_bases
ATGGCTGATCTCGCAGCCGGTGTCGCCGAGCGCGGTCCGCGACTGTCGCTGTGGTCGAGTCTGGATCAGCGGCTCGTCTG
GGTGGTGGCGGCCACGGCGTTGCTCGGTCTGGTCATGGTGGCCTCGGCCTCGATCTCGATGGCCGAGCAGGCCACCGGCG
ATCCGTTCTACTTCTTCAAGCGCCAGATCTTCTTCGCCCTGCTCGGGCTGGGTATGGCCCTGGCGCTGCTGCAGATCCCG
CTGGCCACCTGGGAACGGGCCGGCCCAGGGCTGCTGCTCGGCGCCCTGGCGCTGCTGGTCCTGGTGCTGATCCCCGGCGT
GGGGCGCGAGGTCAACGGCGCCGTGCGCTGGATCCCCTTGGGCGTGTTCAATCTGCAGGTCGCCGAGGTGGTCAAGGTCC
TGCTGGCCCTCTACCTGGCCGGGTTCCTGGTGCGCCGGCAGCAGCAGCTGCGCACCTCCATGGCGGCATTCCTGGTGCCG
GTGCTGGTCTCGGCGGCGTGCGCCTTCCTGCTGCTGCTGCAGCCGGACTTCGGGACTGCCCTGATGCTCATGGCGCTGGC
GGTGGGGTTGCTCTACCTCGCCGGGGCGCCGCTGTGGCGGTTCGCGGCTCTGGTGGGGGTGCTCGCCGCCGCCGCGGCGG
CGCTGGTGGTCTACTCGCCGTACCGCTGGCAGCGGGTCACCGCCTTCATGGATCCCTGGTCCGACCCGTTCAATACCGGA
TTCCAGCTCACCCAGTCGCTGATCGCCATCGGCCGCGGCGATTGGCTGGGCGTGGGCTTGGGCGGCAGCGTGCAGAAGCT
CTTCTATCTGCCCGAGGCGCACACCGACTTCGTCTTCTCGGTGCTCGCCGAAGAGCTGGGCTGGCTCGGTGTGCTCGCCG
TGGTTCTGCTGTTCTCCTACATCGTCTGGCGGGCCATGGCCGTGGGCTGGCAGTGCCACCGCCATCGGCTGCCGTTCGCC
GGCTATCTCGCCTGGGCCGTGGGGCTGGCCCTCGGGCTGCAGGCGTTCATCAACATGGGGGTGGCCACCGGTCTGCTGCC
CACCAAGGGGCTGACCCTGCCGCTGTTCAGCTACGGCGGGAGCAGTGCCCTGGCGACCGGTGCCATGGTTGGGCTGCTGC
TGCGCTGCGGCTACGAGCTGGCCCAGGCACGGGCCGAGGGGCGGCGCCCCGAGGAGGCGGCGTCATGA

Upstream 100 bases:

>100_bases
GCCGTTCTCTTGGCACCGGCATGCGCCAGTTTTGACGCCTTCAGCAGCTTCGAGGCACGCGGCGATGCGTTCCGTGACGC
CGTCCGCGGGGAGGTGGCCC

Downstream 100 bases:

>100_bases
GCGTCCGGACCGTGGCCATCGCCGCCGGCGGAACCGGCGGCCATGTCTACCCCGGCCTGGCCGTGGCCGATGCGCTGCGC
GAACGGGGGCATCGGGTGGT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MADLAAGVAERGPRLSLWSSLDQRLVWVVAATALLGLVMVASASISMAEQATGDPFYFFKRQIFFALLGLGMALALLQIP
LATWERAGPGLLLGALALLVLVLIPGVGREVNGAVRWIPLGVFNLQVAEVVKVLLALYLAGFLVRRQQQLRTSMAAFLVP
VLVSAACAFLLLLQPDFGTALMLMALAVGLLYLAGAPLWRFAALVGVLAAAAAALVVYSPYRWQRVTAFMDPWSDPFNTG
FQLTQSLIAIGRGDWLGVGLGGSVQKLFYLPEAHTDFVFSVLAEELGWLGVLAVVLLFSYIVWRAMAVGWQCHRHRLPFA
GYLAWAVGLALGLQAFINMGVATGLLPTKGLTLPLFSYGGSSALATGAMVGLLLRCGYELAQARAEGRRPEEAAS

Sequences:

>Translated_395_residues
MADLAAGVAERGPRLSLWSSLDQRLVWVVAATALLGLVMVASASISMAEQATGDPFYFFKRQIFFALLGLGMALALLQIP
LATWERAGPGLLLGALALLVLVLIPGVGREVNGAVRWIPLGVFNLQVAEVVKVLLALYLAGFLVRRQQQLRTSMAAFLVP
VLVSAACAFLLLLQPDFGTALMLMALAVGLLYLAGAPLWRFAALVGVLAAAAAALVVYSPYRWQRVTAFMDPWSDPFNTG
FQLTQSLIAIGRGDWLGVGLGGSVQKLFYLPEAHTDFVFSVLAEELGWLGVLAVVLLFSYIVWRAMAVGWQCHRHRLPFA
GYLAWAVGLALGLQAFINMGVATGLLPTKGLTLPLFSYGGSSALATGAMVGLLLRCGYELAQARAEGRRPEEAAS
>Mature_394_residues
ADLAAGVAERGPRLSLWSSLDQRLVWVVAATALLGLVMVASASISMAEQATGDPFYFFKRQIFFALLGLGMALALLQIPL
ATWERAGPGLLLGALALLVLVLIPGVGREVNGAVRWIPLGVFNLQVAEVVKVLLALYLAGFLVRRQQQLRTSMAAFLVPV
LVSAACAFLLLLQPDFGTALMLMALAVGLLYLAGAPLWRFAALVGVLAAAAAALVVYSPYRWQRVTAFMDPWSDPFNTGF
QLTQSLIAIGRGDWLGVGLGGSVQKLFYLPEAHTDFVFSVLAEELGWLGVLAVVLLFSYIVWRAMAVGWQCHRHRLPFAG
YLAWAVGLALGLQAFINMGVATGLLPTKGLTLPLFSYGGSSALATGAMVGLLLRCGYELAQARAEGRRPEEAAS

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=372, Percent_Identity=45.4301075268817, Blast_Score=320, Evalue=8e-89,
Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=32.9341317365269, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42219; Mature: 42087

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLAAGVAERGPRLSLWSSLDQRLVWVVAATALLGLVMVASASISMAEQATGDPFYFFK
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQIFFALLGLGMALALLQIPLATWERAGPGLLLGALALLVLVLIPGVGREVNGAVRWIPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
GVFNLQVAEVVKVLLALYLAGFLVRRQQQLRTSMAAFLVPVLVSAACAFLLLLQPDFGTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LMLMALAVGLLYLAGAPLWRFAALVGVLAAAAAALVVYSPYRWQRVTAFMDPWSDPFNTG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
FQLTQSLIAIGRGDWLGVGLGGSVQKLFYLPEAHTDFVFSVLAEELGWLGVLAVVLLFSY
HHHHHHHHHHCCCCEEEECCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRAMAVGWQCHRHRLPFAGYLAWAVGLALGLQAFINMGVATGLLPTKGLTLPLFSYGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHCCCCC
SSALATGAMVGLLLRCGYELAQARAEGRRPEEAAS
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADLAAGVAERGPRLSLWSSLDQRLVWVVAATALLGLVMVASASISMAEQATGDPFYFFK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQIFFALLGLGMALALLQIPLATWERAGPGLLLGALALLVLVLIPGVGREVNGAVRWIPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
GVFNLQVAEVVKVLLALYLAGFLVRRQQQLRTSMAAFLVPVLVSAACAFLLLLQPDFGTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LMLMALAVGLLYLAGAPLWRFAALVGVLAAAAAALVVYSPYRWQRVTAFMDPWSDPFNTG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
FQLTQSLIAIGRGDWLGVGLGGSVQKLFYLPEAHTDFVFSVLAEELGWLGVLAVVLLFSY
HHHHHHHHHHCCCCEEEECCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRAMAVGWQCHRHRLPFAGYLAWAVGLALGLQAFINMGVATGLLPTKGLTLPLFSYGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHCCCCC
SSALATGAMVGLLLRCGYELAQARAEGRRPEEAAS
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]