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The map label for this gene is murG

Identifier: 121998870

GI number: 121998870

Start: 2295204

End: 2296280

Strand: Reverse

Name: murG

Synonym: Hhal_2091

Alternate gene names: 121998870

Gene position: 2296280-2295204 (Counterclockwise)

Preceding gene: 121998871

Following gene: 121998869

Centisome position: 85.73

GC content: 74.56

Gene sequence:

>1077_bases
ATGAGCGTCCGGACCGTGGCCATCGCCGCCGGCGGAACCGGCGGCCATGTCTACCCCGGCCTGGCCGTGGCCGATGCGCT
GCGCGAACGGGGGCATCGGGTGGTCTGGTTGGGCACCCGCGCCGGCCTGGAGGGGCGCGTCGTTCCCGCTGCCGGCCTCG
ACGCAGAGTGGCTGGAGATCGGCGGGATGCGCGGCAAAGGGCTGGCGACGATAGCGGCGCTGCCCTGGCGTCTGGGGCGT
GCCGTGGCGGTGGCCGGGGCTGCGCTGCGGCGCCAGCGCCCGGATGTGGTCCTCGGCATGGGCGGCTACGTAGCCGGGCC
TGTGGGTCTGGCCGCCCGACTCGCCGGACGGCCCCTGATCATCCACGAACAGAATGCCCGGGCGGGCATGACCAACCGCT
TCCTGGCCCGGCTGGGGCACCGGGTGCTCACCGGCTTTCCCGATGCCCTGGGAGCGCGGAGCGAGTGGGTGGGCAATCCC
ATTCGCACGCGCATCCATCGGCTGGAGTCGCCGCAGGAACGGTACGCCAGGCGCGAGGGGGCGCCGCGGGTGCTGGTGCT
CGGAGGCAGCCAGGGGGCGCGAGCGCTCAACCGTTACGTACCGCAGGCGCTCTCGGCCATCGGCGGTGGGCAGCCTCAGG
TGCTGCACCAGGCGGGCGAGTTGACCCTGGAGGAGGCGCGCACCGAGTACGGCCGCGCCGGTCTGGACGGGGCCGAGGTC
GTGCCCTTTATCGAGGATATGGCGGGCGCGTACGCCTGGGCGGATCTGGTCGTCGCCCGGTCCGGCGCCCTCACCGTGGC
GGAGCTGGCCGCGGCCGGCGTGCCGGCGGTGCTGGTGCCGCTCCCCTGGGCCGTGGACGACCACCAGACGGCCAACGCCG
AATGGCTTTGCGCCGCCGGGGCCGCGCGCAGGCTGCTCCAGCCCGATCTGGAGCAGGGGGCGCTGGGGCCTGTGCTGGCC
GAGCTGCTCGGCGACCGGCGTCGTCTGGCGGAGATGGGTGAGGCGGCGCGTGGCGTGGCCCGTCCGGACGCCACGGACCG
CGTGGCGACGATCTGTGAGGAGGTGGCCCATGGCTGA

Upstream 100 bases:

>100_bases
GTGCCCTGGCGACCGGTGCCATGGTTGGGCTGCTGCTGCGCTGCGGCTACGAGCTGGCCCAGGCACGGGCCGAGGGGCGG
CGCCCCGAGGAGGCGGCGTC

Downstream 100 bases:

>100_bases
TGGCGTTCCCGCCCGCGAGCCGCGTTTCACCGCGCCGATGGACGGCCGCAGTACCTTCGGCCGGGTGCGGCGTATCCACT
TCGTGGGCATCGGCGGGGCC

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEIGGMRGKGLATIAALPWRLGR
AVAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLIIHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNP
IRTRIHRLESPQERYARREGAPRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEV
VPFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAGAARRLLQPDLEQGALGPVLA
ELLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG

Sequences:

>Translated_358_residues
MSVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEIGGMRGKGLATIAALPWRLGR
AVAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLIIHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNP
IRTRIHRLESPQERYARREGAPRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEV
VPFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAGAARRLLQPDLEQGALGPVLA
ELLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG
>Mature_357_residues
SVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEIGGMRGKGLATIAALPWRLGRA
VAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLIIHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNPI
RTRIHRLESPQERYARREGAPRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEVV
PFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAGAARRLLQPDLEQGALGPVLAE
LLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=353, Percent_Identity=47.3087818696884, Blast_Score=284, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_HALHL (A1WYU3)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003657.1
- ProteinModelPortal:   A1WYU3
- SMR:   A1WYU3
- STRING:   A1WYU3
- GeneID:   4709975
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2091
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A1WYU3
- BioCyc:   HHAL349124:HHAL_2091-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37511; Mature: 37379

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEI
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCHHHHHH
GGMRGKGLATIAALPWRLGRAVAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEE
IHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNPIRTRIHRLESPQERYARREG
EECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHCCCHHHHHHHHCC
APRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEV
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VPFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEHHH
AARRLLQPDLEQGALGPVLAELLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG
HHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEI
CCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCCCHHHHHH
GGMRGKGLATIAALPWRLGRAVAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEE
IHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNPIRTRIHRLESPQERYARREG
EECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHCCCHHHHHHHHCC
APRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEV
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VPFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEHHH
AARRLLQPDLEQGALGPVLAELLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG
HHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA