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The map label for this gene is nuoG [H]

Identifier: 121998538

GI number: 121998538

Start: 1932301

End: 1934688

Strand: Reverse

Name: nuoG [H]

Synonym: Hhal_1759

Alternate gene names: 121998538

Gene position: 1934688-1932301 (Counterclockwise)

Preceding gene: 121998539

Following gene: 121998537

Centisome position: 72.23

GC content: 70.73

Gene sequence:

>2388_bases
ATGAGTGCGAACGAGGAGACGGTCACCATCGAGGTCGATGGCTGCTCCATCGAGGCCCGCAAGGGCGAGATGCTGATTCA
GGCCACCGACCGTCATGGGATCCACATCCCGCGGTTCTGCTATCACAAGCACCTCTCCGTGGTGGCCAACTGCCGGATGT
GCCTGGTCGAGGTCGAGAAGGCGCCCAAGCCGCTGCCGGCCTGCGCGACCTCGGTGGCCGACGGCATGGTGGTGCGCACT
GCGTCGGAAACGGCCATCAAGGCGCAGCGCGGCGTCATGGAGTTCCTGCTGATCAACCACCCGCTCGATTGCCCGATCTG
TGATCAGGGCGGCGAGTGCGAACTGCAGGACCTCTCCATGGGGTATGGCCGCGGTATTTCACGCTTCACCGAGGGCAAGC
GGGCGGTGGCCGACGAAGACCTCGGGCCGCTGGTTGCTACCGAGATGACGCGTTGCATCCACTGCACGCGCTGCGTCCGT
TTCCTCGACGAGGTCGCCGGGCAGAAGGAGCTCGGTGGTATGGGCCGTGGGGAGCACACCGAGATCTCGACGTATGTCGA
ATCCGGCCTGAACTCGGAGCTCTCGGCCAATGTGGTCGATGTTTGCCCGGTGGGGGCGCTGACCAATAAGCCGTTTCGCT
TCCGCGCCCGCCCCTGGGAGTTGCTCAGCTTCCCGGCGGTCTCTCCTCACGACGGGGTGGGGTCGAATCTGGCCCTGCAC
ACCCTGCGGGGACGGATCCAGCGCGTCGTGCCGCGTGAGAACGAGGCCGTCAACGAGACGTGGATCGCTGACCGCGACCG
CTTCGCCATCGAGGGGGTTGAGCACGCCGATCGGCTCGAACGGCCCATGCTCAAGCGCGACGGCCGTTGGCACGAGGTGC
CCTGGGAGACCGCCCTGGATCGCGCCGCGGGCGCCCTGCAGGGCGTCGTCCAGCGCCACGGGACCGATGCGCTCGGTGGA
CTGCTGGCGCCGAGCGCGACCCTGGAGGAGCTCTATCTGGCCGCGCGCCTGCTGCGTGGGCTGGGCAGCGGCAACGTCGA
CCACCGCCTGCGCGAGGTGGACACCTCCGACCAGGAGCAGGCGCCGCCCTTCCCGTATCTGGGGCAGAGCATCGCCGAGC
TGGAGCAGGTGGACGCCGCGCTGCTGGTTGGCGCGTACACCCGACACGAGCAGCCACTGATCCATCACCGCCTGCGCAAG
GCGGCCCGGGCGGGCGCTCAGGTCATGGCCCTCAACCCCCGGCGCTTCGACTGGAACCTGCCGCTGGCTGTGGAGCGGGC
CGTGGCGCCGGCGCAGCTGGTCGCCGAGCTCGGTGCCGTGGCGGCGGCCCTGGCCGAGGGGTCAGGGCGTGCGCTGCCGG
AGGGGCTGGCCGAGGTGGCCGGCCCGGTGACCGACTCCGCCCGGGAGGTTGCGCGCCGGCTGGCTGCGGCCGAGCGGCCC
ACGGTCCTGCTCGGCAGCCTGGCGAACAGCCATCCACAGGGTGCAGCGCTGCGGGCATTGGGCGGTTGCATCGCGGAGCT
GGCCAACGGTCGTCTGGGGGTCCTCGCCGAGGCTGGCAATACCGCCGGCGGCTGGGTCGCCGGCGCGGTGCCGCACCGTG
AGGCCGGCGGTGCGCCGGCACGACCGGCGGGGCGCAGTGCCGACGGCATGCTGCGCGCCGGCCTCAAGGGTTATCTCTTG
TTGAATGTGGAGCCGACCCGCGACCTGTGGGATCCGCAAGCCGCCCGGCAGGCGATGGAGCAAGCCGAGGAGGTGGTGGC
GGTGACCGCCTTCGCGGATGAACAACTGCGCGCCCAGGCCGACGTCCTGCTGCCGATGGGGGCATTCGGCGAGAGCGCCG
GCACCTACGTCAACAACGAAGGCCGCTGGCAAAGTTGCCGCGGGGTCGCCGAGCCTCAGGGTGAGGCACGGCCCGGCTGG
CGAATCCTGCGTGCCCTGGGCACGGTTTTGGGGCTGGAGCGTTTCGAGTACAACGACATCGCCGACGTATACGGCGAGCT
CGCCGGTCTGTGTCGGGATCTGGAGCCTGGCTCCCGGTATCCGGCCAGGGCGGTGACCGCTCCGGCGTCCCCTGGGCAGG
GTCTGGCGCTGGCCGGTGGGGTGCCGATCTATGCCGGCGACCCGCTGGTGCGCCGTTCCTTGCCGCTGCAGCAGGCACCG
ATCGCCGGTCGAGCCGAGGTGGTGCTGGCTGCGCAGACGGCCGCCGAACTCGGGTTTTCCGAGGCGCAGCCGCGCTGCGT
CCGGGTGCGTTCGGACAGCGGGGTGGCGGAATTGCCGCTGGTCGTCGACGACGCCGTGCCGGCAGGCGTGGCCTGGATCC
CCGCCGGGCTGGATGAGCGCGCGGCGCTCGGCGGCCCGTACGGGACCGTCTCGCTGGAAGCGCTCTAG

Upstream 100 bases:

>100_bases
GCGAAGCGGCGGCCACGCCTGTGCAGAGTTTCATTCAGCATTTCCGGCACGAGTTCGAACACTACATCGAGCACGGTCGA
TCCCCGGTGGAGGCGGCGGC

Downstream 100 bases:

>100_bases
GCCGCAGGGCCGCAGAAAAGGACGATCGAGGGCATGTACGAGACACTCTTCTGGCAGTTCGCCAAGATCTGGGCCGTCCT
GATCCCGCTGTTCCTGGCCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 795; Mature: 794

Protein sequence:

>795_residues
MSANEETVTIEVDGCSIEARKGEMLIQATDRHGIHIPRFCYHKHLSVVANCRMCLVEVEKAPKPLPACATSVADGMVVRT
ASETAIKAQRGVMEFLLINHPLDCPICDQGGECELQDLSMGYGRGISRFTEGKRAVADEDLGPLVATEMTRCIHCTRCVR
FLDEVAGQKELGGMGRGEHTEISTYVESGLNSELSANVVDVCPVGALTNKPFRFRARPWELLSFPAVSPHDGVGSNLALH
TLRGRIQRVVPRENEAVNETWIADRDRFAIEGVEHADRLERPMLKRDGRWHEVPWETALDRAAGALQGVVQRHGTDALGG
LLAPSATLEELYLAARLLRGLGSGNVDHRLREVDTSDQEQAPPFPYLGQSIAELEQVDAALLVGAYTRHEQPLIHHRLRK
AARAGAQVMALNPRRFDWNLPLAVERAVAPAQLVAELGAVAAALAEGSGRALPEGLAEVAGPVTDSAREVARRLAAAERP
TVLLGSLANSHPQGAALRALGGCIAELANGRLGVLAEAGNTAGGWVAGAVPHREAGGAPARPAGRSADGMLRAGLKGYLL
LNVEPTRDLWDPQAARQAMEQAEEVVAVTAFADEQLRAQADVLLPMGAFGESAGTYVNNEGRWQSCRGVAEPQGEARPGW
RILRALGTVLGLERFEYNDIADVYGELAGLCRDLEPGSRYPARAVTAPASPGQGLALAGGVPIYAGDPLVRRSLPLQQAP
IAGRAEVVLAAQTAAELGFSEAQPRCVRVRSDSGVAELPLVVDDAVPAGVAWIPAGLDERAALGGPYGTVSLEAL

Sequences:

>Translated_795_residues
MSANEETVTIEVDGCSIEARKGEMLIQATDRHGIHIPRFCYHKHLSVVANCRMCLVEVEKAPKPLPACATSVADGMVVRT
ASETAIKAQRGVMEFLLINHPLDCPICDQGGECELQDLSMGYGRGISRFTEGKRAVADEDLGPLVATEMTRCIHCTRCVR
FLDEVAGQKELGGMGRGEHTEISTYVESGLNSELSANVVDVCPVGALTNKPFRFRARPWELLSFPAVSPHDGVGSNLALH
TLRGRIQRVVPRENEAVNETWIADRDRFAIEGVEHADRLERPMLKRDGRWHEVPWETALDRAAGALQGVVQRHGTDALGG
LLAPSATLEELYLAARLLRGLGSGNVDHRLREVDTSDQEQAPPFPYLGQSIAELEQVDAALLVGAYTRHEQPLIHHRLRK
AARAGAQVMALNPRRFDWNLPLAVERAVAPAQLVAELGAVAAALAEGSGRALPEGLAEVAGPVTDSAREVARRLAAAERP
TVLLGSLANSHPQGAALRALGGCIAELANGRLGVLAEAGNTAGGWVAGAVPHREAGGAPARPAGRSADGMLRAGLKGYLL
LNVEPTRDLWDPQAARQAMEQAEEVVAVTAFADEQLRAQADVLLPMGAFGESAGTYVNNEGRWQSCRGVAEPQGEARPGW
RILRALGTVLGLERFEYNDIADVYGELAGLCRDLEPGSRYPARAVTAPASPGQGLALAGGVPIYAGDPLVRRSLPLQQAP
IAGRAEVVLAAQTAAELGFSEAQPRCVRVRSDSGVAELPLVVDDAVPAGVAWIPAGLDERAALGGPYGTVSLEAL
>Mature_794_residues
SANEETVTIEVDGCSIEARKGEMLIQATDRHGIHIPRFCYHKHLSVVANCRMCLVEVEKAPKPLPACATSVADGMVVRTA
SETAIKAQRGVMEFLLINHPLDCPICDQGGECELQDLSMGYGRGISRFTEGKRAVADEDLGPLVATEMTRCIHCTRCVRF
LDEVAGQKELGGMGRGEHTEISTYVESGLNSELSANVVDVCPVGALTNKPFRFRARPWELLSFPAVSPHDGVGSNLALHT
LRGRIQRVVPRENEAVNETWIADRDRFAIEGVEHADRLERPMLKRDGRWHEVPWETALDRAAGALQGVVQRHGTDALGGL
LAPSATLEELYLAARLLRGLGSGNVDHRLREVDTSDQEQAPPFPYLGQSIAELEQVDAALLVGAYTRHEQPLIHHRLRKA
ARAGAQVMALNPRRFDWNLPLAVERAVAPAQLVAELGAVAAALAEGSGRALPEGLAEVAGPVTDSAREVARRLAAAERPT
VLLGSLANSHPQGAALRALGGCIAELANGRLGVLAEAGNTAGGWVAGAVPHREAGGAPARPAGRSADGMLRAGLKGYLLL
NVEPTRDLWDPQAARQAMEQAEEVVAVTAFADEQLRAQADVLLPMGAFGESAGTYVNNEGRWQSCRGVAEPQGEARPGWR
ILRALGTVLGLERFEYNDIADVYGELAGLCRDLEPGSRYPARAVTAPASPGQGLALAGGVPIYAGDPLVRRSLPLQQAPI
AGRAEVVLAAQTAAELGFSEAQPRCVRVRSDSGVAELPLVVDDAVPAGVAWIPAGLDERAALGGPYGTVSLEAL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=682, Percent_Identity=37.2434017595308, Blast_Score=403, Evalue=1e-112,
Organism=Escherichia coli, GI145693161, Length=781, Percent_Identity=26.5044814340589, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI3868721, Length=458, Percent_Identity=23.3624454148472, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17565758, Length=689, Percent_Identity=36.8650217706821, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI32566231, Length=650, Percent_Identity=37.0769230769231, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI193209088, Length=256, Percent_Identity=51.953125, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640559, Length=670, Percent_Identity=38.5074626865672, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24640557, Length=670, Percent_Identity=38.5074626865672, Blast_Score=400, Evalue=1e-111,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 84661; Mature: 84530

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANEETVTIEVDGCSIEARKGEMLIQATDRHGIHIPRFCYHKHLSVVANCRMCLVEVEK
CCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
APKPLPACATSVADGMVVRTASETAIKAQRGVMEFLLINHPLDCPICDQGGECELQDLSM
CCCCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCC
GYGRGISRFTEGKRAVADEDLGPLVATEMTRCIHCTRCVRFLDEVAGQKELGGMGRGEHT
CCCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCH
EISTYVESGLNSELSANVVDVCPVGALTNKPFRFRARPWELLSFPAVSPHDGVGSNLALH
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEECCCCHHHEECCCCCCCCCCCCCHHHH
TLRGRIQRVVPRENEAVNETWIADRDRFAIEGVEHADRLERPMLKRDGRWHEVPWETALD
HHHHHHHHHCCCCCCCCCHHHCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
RAAGALQGVVQRHGTDALGGLLAPSATLEELYLAARLLRGLGSGNVDHRLREVDTSDQEQ
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
APPFPYLGQSIAELEQVDAALLVGAYTRHEQPLIHHRLRKAARAGAQVMALNPRRFDWNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PLAVERAVAPAQLVAELGAVAAALAEGSGRALPEGLAEVAGPVTDSAREVARRLAAAERP
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TVLLGSLANSHPQGAALRALGGCIAELANGRLGVLAEAGNTAGGWVAGAVPHREAGGAPA
EEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCC
RPAGRSADGMLRAGLKGYLLLNVEPTRDLWDPQAARQAMEQAEEVVAVTAFADEQLRAQA
CCCCCCCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
DVLLPMGAFGESAGTYVNNEGRWQSCRGVAEPQGEARPGWRILRALGTVLGLERFEYNDI
HEEEECCCCCCCCCCEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
ADVYGELAGLCRDLEPGSRYPARAVTAPASPGQGLALAGGVPIYAGDPLVRRSLPLQQAP
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCEECCCHHHHHCCCCCCCC
IAGRAEVVLAAQTAAELGFSEAQPRCVRVRSDSGVAELPLVVDDAVPAGVAWIPAGLDER
CCCCCEEEEEEHHHHHCCCCCCCCCEEEEECCCCCEECCEEEECCCCCCEEEECCCCCCH
AALGGPYGTVSLEAL
HHCCCCCCCEEEEEC
>Mature Secondary Structure 
SANEETVTIEVDGCSIEARKGEMLIQATDRHGIHIPRFCYHKHLSVVANCRMCLVEVEK
CCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
APKPLPACATSVADGMVVRTASETAIKAQRGVMEFLLINHPLDCPICDQGGECELQDLSM
CCCCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCC
GYGRGISRFTEGKRAVADEDLGPLVATEMTRCIHCTRCVRFLDEVAGQKELGGMGRGEHT
CCCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCH
EISTYVESGLNSELSANVVDVCPVGALTNKPFRFRARPWELLSFPAVSPHDGVGSNLALH
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEECCCCHHHEECCCCCCCCCCCCCHHHH
TLRGRIQRVVPRENEAVNETWIADRDRFAIEGVEHADRLERPMLKRDGRWHEVPWETALD
HHHHHHHHHCCCCCCCCCHHHCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
RAAGALQGVVQRHGTDALGGLLAPSATLEELYLAARLLRGLGSGNVDHRLREVDTSDQEQ
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
APPFPYLGQSIAELEQVDAALLVGAYTRHEQPLIHHRLRKAARAGAQVMALNPRRFDWNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PLAVERAVAPAQLVAELGAVAAALAEGSGRALPEGLAEVAGPVTDSAREVARRLAAAERP
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TVLLGSLANSHPQGAALRALGGCIAELANGRLGVLAEAGNTAGGWVAGAVPHREAGGAPA
EEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCC
RPAGRSADGMLRAGLKGYLLLNVEPTRDLWDPQAARQAMEQAEEVVAVTAFADEQLRAQA
CCCCCCCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
DVLLPMGAFGESAGTYVNNEGRWQSCRGVAEPQGEARPGWRILRALGTVLGLERFEYNDI
HEEEECCCCCCCCCCEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
ADVYGELAGLCRDLEPGSRYPARAVTAPASPGQGLALAGGVPIYAGDPLVRRSLPLQQAP
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCEECCCHHHHHCCCCCCCC
IAGRAEVVLAAQTAAELGFSEAQPRCVRVRSDSGVAELPLVVDDAVPAGVAWIPAGLDER
CCCCCEEEEEEHHHHHCCCCCCCCCEEEEECCCCCEECCEEEECCCCCCEEEECCCCCCH
AALGGPYGTVSLEAL
HHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA