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The map label for this gene is hrcA [H]

Identifier: 121998260

GI number: 121998260

Start: 1599337

End: 1600392

Strand: Reverse

Name: hrcA [H]

Synonym: Hhal_1478

Alternate gene names: 121998260

Gene position: 1600392-1599337 (Counterclockwise)

Preceding gene: 121998263

Following gene: 121998259

Centisome position: 59.75

GC content: 66.48

Gene sequence:

>1056_bases
ATGAGCCCGCCGCACGATCTGGAGCTGGGCGACCGCGCGCGTATCCTGCTCCGCACGCTGGTGCGTCGCTACATCGACAG
CGGCAGACCGGTCGGCTCGCGGAGCCTTGCCCGCGATGCGGGGCTCTCCGTTAGCCCGGCGACCATCCGCAACGTCATGG
CCGATCTCGAAGAGCTCGGGTACCTGGTTGCGCCGCACACCTCGGCCGGGCGGGTGCCCACCGACCGCGGCTTGCGCTTC
TATGTTGACTGCCTGTTGCAGGTGCAGCCCATCGGGGGGGATACCGTCGAGCGGCTGCGCCAGCGCCTGGCCCGTGACCG
GGACGAGGGCGCGGAAGAGCTAGCGGACTCCGCCTCGGATCTGCTCTCGCAGCTGACCCGCCTGGCCGGGGTCGTGACTC
TGCCGCGCTGCGACTGGGCGGTACTGCGCCACGTGGAGTTCCTGCCTTTATCCGATTGCCGAGTGCTGGCGATCCTGGTG
ATCAACGAACGGGATGTGCAGAATCGCGTCATTCGTACCGAGCGCGATTTCTCCGAAGCGGAGCTTCAGCGCATCGCCAA
CTACCTCAATGCCGAGTTCGCCGGTTTGGAGCTGCCGCGGGTGCGCCAAAGCCTGCTGGCGGCCATGCAGGCGGATCAAC
AGCGGCTCGATGAGTTGATGCGCTCGGCGGTGGAGGTCGGCGAGAAGGCCCTGGCCGAAGAGCAGGATGACGAGGGCTAC
GTCGTGGCCGGCCAGACCAACCTGATGGAGTTTGAAGAGCTCTCCGATGTCGATCGGCTGCGACAGCTGTTCGAGGCTTT
CACGCAGAAGCGCGATATCCTGCATCTCCTCGATCGCTGTGCACGGGCCGACGGTGTCCAGATCTACATCGGCCAGGAGG
CCGGTTACGAGGTCTTTGACGGCCTCTCGCTGGTGACCGCGCGCTACGGGGTCGCCGGCGAAGCCGCCGGGGTGCTCGGT
GTCATCGGTCCGACCCGCATGGCCTACGATCGGATCATCCCGATCGTCGATGTCACCGCCCGTTTGGTGGGGTCGGCCTT
GAATCCGCCCCGTTAG

Upstream 100 bases:

>100_bases
GCGTTGACGGTCGCTTGTGGGGCTTGCTAGCCTCACCTGGCACTCGCTAGGGGTGAGTGCAAACCCTCCGCGAAATCGCG
CAACCAGTGGTGCATGAGCC

Downstream 100 bases:

>100_bases
ATCCCCACACCTGTGTCCAGGCAGGAGACAGCGCACCCGGCCGAGGCGCCCGAGCCGTCGGGCGGTGCGCTGCGTGTTGA
CCGTTTTCTGGCTCAATCCA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSPPHDLELGDRARILLRTLVRRYIDSGRPVGSRSLARDAGLSVSPATIRNVMADLEELGYLVAPHTSAGRVPTDRGLRF
YVDCLLQVQPIGGDTVERLRQRLARDRDEGAEELADSASDLLSQLTRLAGVVTLPRCDWAVLRHVEFLPLSDCRVLAILV
INERDVQNRVIRTERDFSEAELQRIANYLNAEFAGLELPRVRQSLLAAMQADQQRLDELMRSAVEVGEKALAEEQDDEGY
VVAGQTNLMEFEELSDVDRLRQLFEAFTQKRDILHLLDRCARADGVQIYIGQEAGYEVFDGLSLVTARYGVAGEAAGVLG
VIGPTRMAYDRIIPIVDVTARLVGSALNPPR

Sequences:

>Translated_351_residues
MSPPHDLELGDRARILLRTLVRRYIDSGRPVGSRSLARDAGLSVSPATIRNVMADLEELGYLVAPHTSAGRVPTDRGLRF
YVDCLLQVQPIGGDTVERLRQRLARDRDEGAEELADSASDLLSQLTRLAGVVTLPRCDWAVLRHVEFLPLSDCRVLAILV
INERDVQNRVIRTERDFSEAELQRIANYLNAEFAGLELPRVRQSLLAAMQADQQRLDELMRSAVEVGEKALAEEQDDEGY
VVAGQTNLMEFEELSDVDRLRQLFEAFTQKRDILHLLDRCARADGVQIYIGQEAGYEVFDGLSLVTARYGVAGEAAGVLG
VIGPTRMAYDRIIPIVDVTARLVGSALNPPR
>Mature_350_residues
SPPHDLELGDRARILLRTLVRRYIDSGRPVGSRSLARDAGLSVSPATIRNVMADLEELGYLVAPHTSAGRVPTDRGLRFY
VDCLLQVQPIGGDTVERLRQRLARDRDEGAEELADSASDLLSQLTRLAGVVTLPRCDWAVLRHVEFLPLSDCRVLAILVI
NERDVQNRVIRTERDFSEAELQRIANYLNAEFAGLELPRVRQSLLAAMQADQQRLDELMRSAVEVGEKALAEEQDDEGYV
VAGQTNLMEFEELSDVDRLRQLFEAFTQKRDILHLLDRCARADGVQIYIGQEAGYEVFDGLSLVTARYGVAGEAAGVLGV
IGPTRMAYDRIIPIVDVTARLVGSALNPPR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38988; Mature: 38857

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPHDLELGDRARILLRTLVRRYIDSGRPVGSRSLARDAGLSVSPATIRNVMADLEELG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCC
YLVAPHTSAGRVPTDRGLRFYVDCLLQVQPIGGDTVERLRQRLARDRDEGAEELADSASD
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLSQLTRLAGVVTLPRCDWAVLRHVEFLPLSDCRVLAILVINERDVQNRVIRTERDFSEA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCHH
ELQRIANYLNAEFAGLELPRVRQSLLAAMQADQQRLDELMRSAVEVGEKALAEEQDDEGY
HHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VVAGQTNLMEFEELSDVDRLRQLFEAFTQKRDILHLLDRCARADGVQIYIGQEAGYEVFD
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
GLSLVTARYGVAGEAAGVLGVIGPTRMAYDRIIPIVDVTARLVGSALNPPR
HHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPPHDLELGDRARILLRTLVRRYIDSGRPVGSRSLARDAGLSVSPATIRNVMADLEELG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCC
YLVAPHTSAGRVPTDRGLRFYVDCLLQVQPIGGDTVERLRQRLARDRDEGAEELADSASD
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLSQLTRLAGVVTLPRCDWAVLRHVEFLPLSDCRVLAILVINERDVQNRVIRTERDFSEA
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCHH
ELQRIANYLNAEFAGLELPRVRQSLLAAMQADQQRLDELMRSAVEVGEKALAEEQDDEGY
HHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VVAGQTNLMEFEELSDVDRLRQLFEAFTQKRDILHLLDRCARADGVQIYIGQEAGYEVFD
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
GLSLVTARYGVAGEAAGVLGVIGPTRMAYDRIIPIVDVTARLVGSALNPPR
HHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA