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The map label for this gene is ptrB [H]

Identifier: 121998158

GI number: 121998158

Start: 1483363

End: 1485453

Strand: Reverse

Name: ptrB [H]

Synonym: Hhal_1376

Alternate gene names: 121998158

Gene position: 1485453-1483363 (Counterclockwise)

Preceding gene: 121998159

Following gene: 121998155

Centisome position: 55.46

GC content: 70.16

Gene sequence:

>2091_bases
ATGACCGAGTCGACGCCGCAGCCGCCCCGGGCCGCCGAGACCCCCGAGGTGATCGAACGCTTCGGGGTGCGCCGCACCGA
CCCCTACGCCTGGTTGCGCGATCCGAACTGGCGGGAGGCGATGCTCGACCCGCAGCAGCTGCAGTCGTCCATCCGTGCCC
ACCTGGAGGCCGAGAACGCCTACACCGAGGCGGTGCTGCAGCCGGTGGCCGGGCTGCGTGAGCGGCTTTTCGCCGAGCTG
CGCGGGCGGATCAAGGAGGAGGACGCCTCGGTCCCCGATCCCGACGGCGCCTACGAGTACTATGTCCGCTTCCGCGCCGG
CGGGCAGCACCCGGTGGCCTGCCGTCGGCCTCGCGGGGGCGGGGCCGAGGAGGTGCTGCTCGATGGCGACGCCCTGGCCG
AGGGGCACGCTTACTTCCAGCTCGGCGACTGGGCGCACAGCGACGACCACCGCTACCTGGCCTACGCCGTGGATACCAGC
GGTGCCGAGGCGTACACCATTCGCTTTCGGGATCTTGCCGGTGGGGCCGATCTGCCGGATGCCCTGGAGCAGGCCCGCGG
CGACTTCGTCTGGGCCGGCGACGGCCAGACCCTGCTCTATACGGTGCTCGATGACGAGCACCGGCCGCGCTGGGTTTATC
GCCACTGTCTTGGCACCGATTCGGCCAGCGACGCGCTGGTCTACGAGGAGACTGATCCGGGGTTCTTCGTCGGCCTGGAC
CGCACCGAGAGCCGGCGCTACGTGCTCATTGAGACCCACGATCACACCACCTCGGAGGTCCACGCTGCGCTGGCCGACGA
CCCGGCGGCCGGCTTTCGCTGCCTCATGCCCCGCGAGCGCGGGGTGGAGTACGCAGTCAGCGACAGCGGCGACCGCTGGC
TGATCCTGACCAACCGGCAGGCGCAGGACTTCCGCATCGTCCAGGCGCCCCTGGAAGCCCCGGAACCGGGGCATTTCGAA
GAGGTCGTGCCCCACCGCCCCGGGGTGCTGATCCACGATATGCTGCTGTTCCGGGAGCACCTGGTGCGCCTGGAGAGCGA
GGATGCGCTGCCGCGCATCGTGGTCCGTCGTCTGGGCGACGGCGCCGAGCACAGCGTCGCCTTCGACGAGGCGGCCTACG
CGCTGGGCATCTCGGGCGGCTTCGAGTACGACACCACCACCCTGCGCTTCAGCTACTCGTCGTTGACGACGCCGGGCCGG
GTCTACGACTACGACATGGAGACCCGGGTGCGCAGCTTGCGCAAGGAGCAGGAGATCCCTAGCGGGCACGATCCGGCCGC
CTACGTGGCGCACCGCATCGAGGCCACGGCCCCGGATGGTGAGCGGGTGCCGATCTCGCTCGTCCACCGCGCGGATCTGC
AGCCGGGCCCGGATACCCCGCTGTGGCTCAACGGCTACGGTGCCTACGGCATCAGCCAGCCGGCGGCCTTCTCGCCGCAT
CGACTGTCGCTGGTCGACCGCGGCTTCGTCTTCGCCATTGCTCACGTGCGCGGCGGCAAGGAACGCGGCTACCGCTGGTA
CGACGCCGGCAAGCTCGAGCACAAGCCGAATACCTTCAGCGACTACATCGCCTGCGCCGAGCACCTGATCGACGCCGGTT
ACACCGGGGCCGGGCGGGTGGTGGTCCACGGCGGCTCGGCCGGCGGCATGCTCGTCGGCGCCGTGCTCAATCAGCGCCCG
GAGCTCTTCGGGGCCGCGGTGGCGGATGTGCCCTTTGTGGATGTGCTCAACACCATGAGCGACCCGAGCCTGCCGCTCAC
CCCGCCGGAGTGGCCGGAGTGGGGCAACCCCATCGAGGACGAGCGGGCTTTCCATACCATCCTCGGCTACTCGCCCTACG
AGAACATCCAGGCGCAGGCCTATCCGCCCATCCTGGCCACCGCCGGGGTCTCGGATCCGCGGGTGACCTACTGGGAGCCG
GCCAAGTGGGTGGCCCGTCTGCGTGCCCTGAAGACCGACGACAACCCGCTGCTGCTGCAGACCAACATGAGCGCCGGCCA
CGCCGGGCCGGGCGGTCGCTTCGACTACCTGGAGGAGGCGGCCTTGCGCTTTGCCTTCGTGCTCTGGGTCTTCGGCCGGG
CCGTGGGCTGA

Upstream 100 bases:

>100_bases
GCCAACGTCCACGCCAGCGCCTGGCAGTCGGATCCCAAGCGTCCCATCGCTGCGGCGCGGGGGCACTTCCTGCTGACACC
GCCGGAGGGGACCGACTGAT

Downstream 100 bases:

>100_bases
TCGGCCCGCCGCGCAGGGCCCGGCCCGCCGCCGGAGAGATCATCCGGTGACGGGACGAGCCGGCTAGGGCCGCTTCATCC
GCTGGAGCTGCCGGTCGTGG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MTESTPQPPRAAETPEVIERFGVRRTDPYAWLRDPNWREAMLDPQQLQSSIRAHLEAENAYTEAVLQPVAGLRERLFAEL
RGRIKEEDASVPDPDGAYEYYVRFRAGGQHPVACRRPRGGGAEEVLLDGDALAEGHAYFQLGDWAHSDDHRYLAYAVDTS
GAEAYTIRFRDLAGGADLPDALEQARGDFVWAGDGQTLLYTVLDDEHRPRWVYRHCLGTDSASDALVYEETDPGFFVGLD
RTESRRYVLIETHDHTTSEVHAALADDPAAGFRCLMPRERGVEYAVSDSGDRWLILTNRQAQDFRIVQAPLEAPEPGHFE
EVVPHRPGVLIHDMLLFREHLVRLESEDALPRIVVRRLGDGAEHSVAFDEAAYALGISGGFEYDTTTLRFSYSSLTTPGR
VYDYDMETRVRSLRKEQEIPSGHDPAAYVAHRIEATAPDGERVPISLVHRADLQPGPDTPLWLNGYGAYGISQPAAFSPH
RLSLVDRGFVFAIAHVRGGKERGYRWYDAGKLEHKPNTFSDYIACAEHLIDAGYTGAGRVVVHGGSAGGMLVGAVLNQRP
ELFGAAVADVPFVDVLNTMSDPSLPLTPPEWPEWGNPIEDERAFHTILGYSPYENIQAQAYPPILATAGVSDPRVTYWEP
AKWVARLRALKTDDNPLLLQTNMSAGHAGPGGRFDYLEEAALRFAFVLWVFGRAVG

Sequences:

>Translated_696_residues
MTESTPQPPRAAETPEVIERFGVRRTDPYAWLRDPNWREAMLDPQQLQSSIRAHLEAENAYTEAVLQPVAGLRERLFAEL
RGRIKEEDASVPDPDGAYEYYVRFRAGGQHPVACRRPRGGGAEEVLLDGDALAEGHAYFQLGDWAHSDDHRYLAYAVDTS
GAEAYTIRFRDLAGGADLPDALEQARGDFVWAGDGQTLLYTVLDDEHRPRWVYRHCLGTDSASDALVYEETDPGFFVGLD
RTESRRYVLIETHDHTTSEVHAALADDPAAGFRCLMPRERGVEYAVSDSGDRWLILTNRQAQDFRIVQAPLEAPEPGHFE
EVVPHRPGVLIHDMLLFREHLVRLESEDALPRIVVRRLGDGAEHSVAFDEAAYALGISGGFEYDTTTLRFSYSSLTTPGR
VYDYDMETRVRSLRKEQEIPSGHDPAAYVAHRIEATAPDGERVPISLVHRADLQPGPDTPLWLNGYGAYGISQPAAFSPH
RLSLVDRGFVFAIAHVRGGKERGYRWYDAGKLEHKPNTFSDYIACAEHLIDAGYTGAGRVVVHGGSAGGMLVGAVLNQRP
ELFGAAVADVPFVDVLNTMSDPSLPLTPPEWPEWGNPIEDERAFHTILGYSPYENIQAQAYPPILATAGVSDPRVTYWEP
AKWVARLRALKTDDNPLLLQTNMSAGHAGPGGRFDYLEEAALRFAFVLWVFGRAVG
>Mature_695_residues
TESTPQPPRAAETPEVIERFGVRRTDPYAWLRDPNWREAMLDPQQLQSSIRAHLEAENAYTEAVLQPVAGLRERLFAELR
GRIKEEDASVPDPDGAYEYYVRFRAGGQHPVACRRPRGGGAEEVLLDGDALAEGHAYFQLGDWAHSDDHRYLAYAVDTSG
AEAYTIRFRDLAGGADLPDALEQARGDFVWAGDGQTLLYTVLDDEHRPRWVYRHCLGTDSASDALVYEETDPGFFVGLDR
TESRRYVLIETHDHTTSEVHAALADDPAAGFRCLMPRERGVEYAVSDSGDRWLILTNRQAQDFRIVQAPLEAPEPGHFEE
VVPHRPGVLIHDMLLFREHLVRLESEDALPRIVVRRLGDGAEHSVAFDEAAYALGISGGFEYDTTTLRFSYSSLTTPGRV
YDYDMETRVRSLRKEQEIPSGHDPAAYVAHRIEATAPDGERVPISLVHRADLQPGPDTPLWLNGYGAYGISQPAAFSPHR
LSLVDRGFVFAIAHVRGGKERGYRWYDAGKLEHKPNTFSDYIACAEHLIDAGYTGAGRVVVHGGSAGGMLVGAVLNQRPE
LFGAAVADVPFVDVLNTMSDPSLPLTPPEWPEWGNPIEDERAFHTILGYSPYENIQAQAYPPILATAGVSDPRVTYWEPA
KWVARLRALKTDDNPLLLQTNMSAGHAGPGGRFDYLEEAALRFAFVLWVFGRAVG

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=702, Percent_Identity=28.0626780626781, Blast_Score=236, Evalue=6e-62,
Organism=Homo sapiens, GI284172420, Length=506, Percent_Identity=31.4229249011858, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI284172413, Length=506, Percent_Identity=31.4229249011858, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI70778815, Length=506, Percent_Identity=31.4229249011858, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI284172438, Length=506, Percent_Identity=31.4229249011858, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI284172431, Length=506, Percent_Identity=31.4229249011858, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI108860686, Length=509, Percent_Identity=30.2554027504912, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=40.8450704225352, Blast_Score=155, Evalue=2e-37,
Organism=Escherichia coli, GI1788150, Length=690, Percent_Identity=38.1159420289855, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24583414, Length=716, Percent_Identity=26.1173184357542, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI221510989, Length=702, Percent_Identity=25.6410256410256, Blast_Score=194, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77325; Mature: 77194

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESTPQPPRAAETPEVIERFGVRRTDPYAWLRDPNWREAMLDPQQLQSSIRAHLEAENA
CCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHH
YTEAVLQPVAGLRERLFAELRGRIKEEDASVPDPDGAYEYYVRFRAGGQHPVACRRPRGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEECCCCC
GAEEVLLDGDALAEGHAYFQLGDWAHSDDHRYLAYAVDTSGAEAYTIRFRDLAGGADLPD
CCCEEEECCCHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCHH
ALEQARGDFVWAGDGQTLLYTVLDDEHRPRWVYRHCLGTDSASDALVYEETDPGFFVGLD
HHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEECCCCEEEEEC
RTESRRYVLIETHDHTTSEVHAALADDPAAGFRCLMPRERGVEYAVSDSGDRWLILTNRQ
CCCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEECCHHHCCEEEECCCCCEEEEEECCC
AQDFRIVQAPLEAPEPGHFEEVVPHRPGVLIHDMLLFREHLVRLESEDALPRIVVRRLGD
CCCEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GAEHSVAFDEAAYALGISGGFEYDTTTLRFSYSSLTTPGRVYDYDMETRVRSLRKEQEIP
CCCCCEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCC
SGHDPAAYVAHRIEATAPDGERVPISLVHRADLQPGPDTPLWLNGYGAYGISQPAAFSPH
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCC
RLSLVDRGFVFAIAHVRGGKERGYRWYDAGKLEHKPNTFSDYIACAEHLIDAGYTGAGRV
EEEEECCCEEEEEEECCCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
VVHGGSAGGMLVGAVLNQRPELFGAAVADVPFVDVLNTMSDPSLPLTPPEWPEWGNPIED
EEECCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
ERAFHTILGYSPYENIQAQAYPPILATAGVSDPRVTYWEPAKWVARLRALKTDDNPLLLQ
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEE
TNMSAGHAGPGGRFDYLEEAALRFAFVLWVFGRAVG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TESTPQPPRAAETPEVIERFGVRRTDPYAWLRDPNWREAMLDPQQLQSSIRAHLEAENA
CCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHH
YTEAVLQPVAGLRERLFAELRGRIKEEDASVPDPDGAYEYYVRFRAGGQHPVACRRPRGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEECCCCC
GAEEVLLDGDALAEGHAYFQLGDWAHSDDHRYLAYAVDTSGAEAYTIRFRDLAGGADLPD
CCCEEEECCCHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCHH
ALEQARGDFVWAGDGQTLLYTVLDDEHRPRWVYRHCLGTDSASDALVYEETDPGFFVGLD
HHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEECCCCEEEEEC
RTESRRYVLIETHDHTTSEVHAALADDPAAGFRCLMPRERGVEYAVSDSGDRWLILTNRQ
CCCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEECCHHHCCEEEECCCCCEEEEEECCC
AQDFRIVQAPLEAPEPGHFEEVVPHRPGVLIHDMLLFREHLVRLESEDALPRIVVRRLGD
CCCEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
GAEHSVAFDEAAYALGISGGFEYDTTTLRFSYSSLTTPGRVYDYDMETRVRSLRKEQEIP
CCCCCEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCC
SGHDPAAYVAHRIEATAPDGERVPISLVHRADLQPGPDTPLWLNGYGAYGISQPAAFSPH
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCC
RLSLVDRGFVFAIAHVRGGKERGYRWYDAGKLEHKPNTFSDYIACAEHLIDAGYTGAGRV
EEEEECCCEEEEEEECCCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
VVHGGSAGGMLVGAVLNQRPELFGAAVADVPFVDVLNTMSDPSLPLTPPEWPEWGNPIED
EEECCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
ERAFHTILGYSPYENIQAQAYPPILATAGVSDPRVTYWEPAKWVARLRALKTDDNPLLLQ
HHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEE
TNMSAGHAGPGGRFDYLEEAALRFAFVLWVFGRAVG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]