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The map label for this gene is ttuD [H]

Identifier: 121998057

GI number: 121998057

Start: 1372819

End: 1374087

Strand: Reverse

Name: ttuD [H]

Synonym: Hhal_1267

Alternate gene names: 121998057

Gene position: 1374087-1372819 (Counterclockwise)

Preceding gene: 121998059

Following gene: 121998056

Centisome position: 51.3

GC content: 71.63

Gene sequence:

>1269_bases
ATGGGCGCGGAGCGCCGGAACCATCGGGAGTGGCTTGAACGCTGGTTTCAGGCGGCTTTGACGGCGGTGGATCCGGCCCG
ATGTCTGCCGCCGATGCTGCCCGAGCCCGGGGCGGGGAAGACGGTGGTGGTTGGGGCCGGCAAGGCGGCGGCCTCGATGG
CTGCCGCCGTCGAGGCGAACTGGCCCGGCCCGCTGAGCGGGACGGTGATCGTACCGTACCGGCATGCGGCGCCCACGCGC
AGCATCGAGGTCCGGGAAGCCGGTCATCCCGTCCCCGATGAGGCCGGCGTGGCCGCCACGCAGCGCCTGCTCGGACAGCT
GGAGGGACTGGAGGAGCGCGATCTGGTCCTGGTGCTGCTCTCCGGTGGCGGATCGGCGCTGTTGACGGCGCCCGCGCCGC
CGCTGACGCTGGCCGATAAACAGGCGACCACGCGGGCGTTGCTGCGCAGCGGTGCGCCGATCGACGCGATCAATACGGTG
CGTCGACACCTGTCGACGGTTAAAGGCGGGCGGCTCGCCCTGCGCGCTCATCCGGCTCGGGTGGTGACCCTGCTGATCTC
CGACGTCCCCGGAGACGATCCGGCGACCATCGCCTCCGGTCCCACCAGTCCGGACAGCTCCACGCCGGAGGACGCGCGCC
GGCTCCTGGACCGCTACGGGGTGCCCTGCGGAACCTCGGTGGCAGAGGCGCTGGATCGGGCGCAGTTGCCTCCGAGGCCC
GATGACCCGCGCCTGCGCCGGGTCTCTTGCCACGTCGTCGCTGGCGCGCAGGCGGCACTTCAGGCGGCGGCACAAGCGGC
GCGGGCGGAGGGGATGACGCCTTTGGTGCTCGGCGACACCATTGAGGGCGAAGCCCGCGAAGTGGCCCGTGTACTCATCG
GGATGGGGCGTTCCTGCCGGCGCTGGGGCGCCCCGGTACCGCCCCCCTGTGTGCTGCTCTCCGGTGGCGAGACCTCAGTG
ACCGTGCGCGGCTCAGGCCGCGGCGGTCGCAATACCGAGCTGGCCCTGGCGGCCGCGCTGGCCGCCGAGGGTATACCGGG
ATTCCACCTGCTTTGCGCGGATACCGACGGGATCGATGGCAGCGAGGACAACGCCGGCGCCGTGGTGGACCCGGCAAGCC
TGGCACGCGCCCGCGCCCATGGACTCGATCCGTGGGCGTACCTGGCCGACAACGACAGCTACGGCCTGTTCAAGGCCGCG
GGGGGGCTGCTTCATACTGGGCCGACTCTGACCAATGTCAACGACTTCCGTGCGCTGCTCATCCCCTGA

Upstream 100 bases:

>100_bases
GCCGGGCGGGCACCCCCGCTTCCGTCTTGCACTGCATTAGAGCATTAGCGGGTCAGGTGTGCAAAGATGCGGGTAGGGCA
TGCAGGAAGCGGAGGTTGCC

Downstream 100 bases:

>100_bases
GTGAATCCCGCGGGCTGTTTTGGGTGTCTCCTCTGCCCGTCATGCACCTAGACTGGGGGGACGCCTGATCAACGACGGTG
GAGGTTGGCGCCATGAGTTT

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MGAERRNHREWLERWFQAALTAVDPARCLPPMLPEPGAGKTVVVGAGKAAASMAAAVEANWPGPLSGTVIVPYRHAAPTR
SIEVREAGHPVPDEAGVAATQRLLGQLEGLEERDLVLVLLSGGGSALLTAPAPPLTLADKQATTRALLRSGAPIDAINTV
RRHLSTVKGGRLALRAHPARVVTLLISDVPGDDPATIASGPTSPDSSTPEDARRLLDRYGVPCGTSVAEALDRAQLPPRP
DDPRLRRVSCHVVAGAQAALQAAAQAARAEGMTPLVLGDTIEGEAREVARVLIGMGRSCRRWGAPVPPPCVLLSGGETSV
TVRGSGRGGRNTELALAAALAAEGIPGFHLLCADTDGIDGSEDNAGAVVDPASLARARAHGLDPWAYLADNDSYGLFKAA
GGLLHTGPTLTNVNDFRALLIP

Sequences:

>Translated_422_residues
MGAERRNHREWLERWFQAALTAVDPARCLPPMLPEPGAGKTVVVGAGKAAASMAAAVEANWPGPLSGTVIVPYRHAAPTR
SIEVREAGHPVPDEAGVAATQRLLGQLEGLEERDLVLVLLSGGGSALLTAPAPPLTLADKQATTRALLRSGAPIDAINTV
RRHLSTVKGGRLALRAHPARVVTLLISDVPGDDPATIASGPTSPDSSTPEDARRLLDRYGVPCGTSVAEALDRAQLPPRP
DDPRLRRVSCHVVAGAQAALQAAAQAARAEGMTPLVLGDTIEGEAREVARVLIGMGRSCRRWGAPVPPPCVLLSGGETSV
TVRGSGRGGRNTELALAAALAAEGIPGFHLLCADTDGIDGSEDNAGAVVDPASLARARAHGLDPWAYLADNDSYGLFKAA
GGLLHTGPTLTNVNDFRALLIP
>Mature_421_residues
GAERRNHREWLERWFQAALTAVDPARCLPPMLPEPGAGKTVVVGAGKAAASMAAAVEANWPGPLSGTVIVPYRHAAPTRS
IEVREAGHPVPDEAGVAATQRLLGQLEGLEERDLVLVLLSGGGSALLTAPAPPLTLADKQATTRALLRSGAPIDAINTVR
RHLSTVKGGRLALRAHPARVVTLLISDVPGDDPATIASGPTSPDSSTPEDARRLLDRYGVPCGTSVAEALDRAQLPPRPD
DPRLRRVSCHVVAGAQAALQAAAQAARAEGMTPLVLGDTIEGEAREVARVLIGMGRSCRRWGAPVPPPCVLLSGGETSVT
VRGSGRGGRNTELALAAALAAEGIPGFHLLCADTDGIDGSEDNAGAVVDPASLARARAHGLDPWAYLADNDSYGLFKAAG
GLLHTGPTLTNVNDFRALLIP

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=440, Percent_Identity=36.8181818181818, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193205461, Length=461, Percent_Identity=30.58568329718, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI19920578, Length=490, Percent_Identity=31.4285714285714, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43689; Mature: 43558

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAERRNHREWLERWFQAALTAVDPARCLPPMLPEPGAGKTVVVGAGKAAASMAAAVEAN
CCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHEECC
WPGPLSGTVIVPYRHAAPTRSIEVREAGHPVPDEAGVAATQRLLGQLEGLEERDLVLVLL
CCCCCCCEEEEEECCCCCCCCEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
SGGGSALLTAPAPPLTLADKQATTRALLRSGAPIDAINTVRRHLSTVKGGRLALRAHPAR
CCCCCEEEECCCCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCE
VVTLLISDVPGDDPATIASGPTSPDSSTPEDARRLLDRYGVPCGTSVAEALDRAQLPPRP
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
DDPRLRRVSCHVVAGAQAALQAAAQAARAEGMTPLVLGDTIEGEAREVARVLIGMGRSCR
CCCCEEEEEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHH
RWGAPVPPPCVLLSGGETSVTVRGSGRGGRNTELALAAALAAEGIPGFHLLCADTDGIDG
HCCCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCC
SEDNAGAVVDPASLARARAHGLDPWAYLADNDSYGLFKAAGGLLHTGPTLTNVNDFRALL
CCCCCCCEECHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCEECCCCCCCCCCCEEEE
IP
CC
>Mature Secondary Structure 
GAERRNHREWLERWFQAALTAVDPARCLPPMLPEPGAGKTVVVGAGKAAASMAAAVEAN
CCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHEECC
WPGPLSGTVIVPYRHAAPTRSIEVREAGHPVPDEAGVAATQRLLGQLEGLEERDLVLVLL
CCCCCCCEEEEEECCCCCCCCEEHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
SGGGSALLTAPAPPLTLADKQATTRALLRSGAPIDAINTVRRHLSTVKGGRLALRAHPAR
CCCCCEEEECCCCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCE
VVTLLISDVPGDDPATIASGPTSPDSSTPEDARRLLDRYGVPCGTSVAEALDRAQLPPRP
EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
DDPRLRRVSCHVVAGAQAALQAAAQAARAEGMTPLVLGDTIEGEAREVARVLIGMGRSCR
CCCCEEEEEEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHH
RWGAPVPPPCVLLSGGETSVTVRGSGRGGRNTELALAAALAAEGIPGFHLLCADTDGIDG
HCCCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCC
SEDNAGAVVDPASLARARAHGLDPWAYLADNDSYGLFKAAGGLLHTGPTLTNVNDFRALL
CCCCCCCEECHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCEECCCCCCCCCCCEEEE
IP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]