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The map label for this gene is recD [H]

Identifier: 121998059

GI number: 121998059

Start: 1376249

End: 1378291

Strand: Reverse

Name: recD [H]

Synonym: Hhal_1269

Alternate gene names: 121998059

Gene position: 1378291-1376249 (Counterclockwise)

Preceding gene: 121998060

Following gene: 121998057

Centisome position: 51.46

GC content: 70.97

Gene sequence:

>2043_bases
GTGAGCGTGCGGGTCGATCAGGAGGCGATCCTCAGGTGGCTGCGTGAGGCCGAGGCGCTGGGCTGGCTGCGCCCGTTGGA
TGGGGCCCTGGCGGAGTTCCTGCGTGAGCAGGTGCCCGATGCGCCGCCGCTGCTGTTGCTGGCCGCAGCGCTGACCAGTC
ATCAGGCGGGCCGTGGGCATGTCTGCCTGGATCTCGATCAGCTCTGGGAACGGGCCGAGCCGGTCCTGAGCCTTCCGCCG
GAGACCGTTGACGCGCCCGAGCCGGTGAAATCGCCCGCGGCACTCCTGGACGCCGCCGGCGGTCGCGATGCGTTCGAGCG
GCAATTGGAGTGCCCGGAACTGGTGGGCAGAGGCCCCGGTTCCACACCGCTGGTCCGCGACGGACCGAGGCTCTATCTGC
GCCGCTACTGGGCCTGCGAGCGCACCATCGCACGGGTGGTGCAGCAGCGCGTGGATGCAGCGGCGCAGTGGCGCGCGCAG
CTCGACCCGGCCACGGTCCGGCGCTGGCTGGATGGGTTGTTCGGCGCGCCTGGGGGCGATGGCCCGGATTGGCAGCGGGT
CGCCTGTGCCGTGGCCGCCGGCAGTGGTTTCAGTGTTATCACCGGCGGACCGGGTACCGGCAAGACTACGACGGTGTTGC
GTCTGCTGGCGTTGCTGCAGGGGCTCCACGGCGGGGCCCTGCGCATCCGCCTGACGGCCCCCACCGGCAAGGCGGCGGCA
CGGCTGAACGCGAGCATCGCCGGGGCGGTGGATCGGCTGGGGCTGGAGGAGCTGGACGGCGGCGCCGAGCTGCGCGCGCG
GATACCCACCGAGGTGGTGACAGTGCACCGGCTGCTGGGCGCAGGCGGTGGACGGCGCTTTCGCCACCACGCCGGGGAAC
CCCTGGCCGCGGATGTGGTGGTCGTGGATGAAGCGTCGATGATCGACGTGGAGTTGATGGCGGCGTTGCTGGAGGCCCTG
CCGGATGGGGGCCGTCTGGTGCTGCTTGGTGACAAGGACCAGTTGGCCTCGGTGGAGGCCGGGGCCATCCTTGGCGAGCT
CTGCGCCCGGGCAGATCAGGGCGGTTATTGGCCCGATACCGCCGAGTGGCTAGAGGCGGTCAGCGGCCAGTGCATCCCGT
CGGCGCTGATCGATCCCACCGGCGGTGGTCTCGACCAGCATGTCGTCATGCTTCGGCACAGCCACCGGTTCGGTGCCGAC
AGCGGGATCGGGCGCTTGGCTCGGGCGGTGAATGCCGGTGATCAGGCGGCGGTCGAGGCTTGGGGGTATGGGCACGAGGG
CGATCTGGCGCGGGTGCAGCTTGCCGACGGAGAGCAAGACCCGACGCTGATCCACTGGGCGGTGGACGGCGGGCAGACCG
GCCTGGGCTACGCCGCTTATCTGAGCGACATCCAGGAACTGCGACCGGGCCCGGATGCCTCCGCTGGGGAGTACGCCGGC
TGGGCCTCGCAGGTGCTGGAGACGCACGGGGCGTTCCAATTGCTGGCGGCGCTGCGGCGCGGACCGTACGGGGTCGAGGC
CCTCAATGAGCGCCTTGCCGCGGCGCTGCGCCAGCGGGGGCTGATCCGAGGTGAGGGGGCCTGGTACGAGGGCCGACCGG
TGATCGTCACGCGCAACGATTACGGCCTGGGGCTGATCAACGGGGATATCGGCATCGCCCTGCGCGTCCCGCGCTTCCTG
GTGCAGAGCCCGGAGGCGGGGGGTGCCGGGGAGGAGCGACAGAAGGTGCTGCGTGTCGCCTTCCGCGCCGCCGATGGCAG
CGGACGCATCCGCTGGGTCCCGCCCCATCGGCTGGAGTCCGTGGAGACGGCATTCGCCTTGACGGTGCACAAGGCCCAGG
GTTCGGAGTTTCGCCACGCAGCCTTATTGCTGCCGGATCGGCCCAGTCCGGTGCTCACCCGTGAGCTCCTCTACACCGGC
ATCACCCGGGCCAGTCAGTGGTTCACCCTGCTGGAGCCGCAACCGGCCGTGCTGAAGGCGGCGGTGCGCCAGCGAACCGT
TCGTGGTGGCGGCCTGCGGGCCATGCTCGAGGCTGCTGGCTAG

Upstream 100 bases:

>100_bases
CGGGGCAGGGCGTGTTCCACGCGCGTCCGCCGCGGGCCCTGATCGAAGAGCTCGATGGGTGGCTGCGCGACGGGCCCGAT
GGGCCGCAGGAGCAGACGCT

Downstream 100 bases:

>100_bases
GCGGCTGCTGCCGCGGCGGGTCCTTAGGCGCTCGAATCCTGCGGGCCGCGAGGCGGTGAGGGCGCAAAAAAAGGCCGCCC
CGGAGGGCGGCCGAACGTCA

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MSVRVDQEAILRWLREAEALGWLRPLDGALAEFLREQVPDAPPLLLLAAALTSHQAGRGHVCLDLDQLWERAEPVLSLPP
ETVDAPEPVKSPAALLDAAGGRDAFERQLECPELVGRGPGSTPLVRDGPRLYLRRYWACERTIARVVQQRVDAAAQWRAQ
LDPATVRRWLDGLFGAPGGDGPDWQRVACAVAAGSGFSVITGGPGTGKTTTVLRLLALLQGLHGGALRIRLTAPTGKAAA
RLNASIAGAVDRLGLEELDGGAELRARIPTEVVTVHRLLGAGGGRRFRHHAGEPLAADVVVVDEASMIDVELMAALLEAL
PDGGRLVLLGDKDQLASVEAGAILGELCARADQGGYWPDTAEWLEAVSGQCIPSALIDPTGGGLDQHVVMLRHSHRFGAD
SGIGRLARAVNAGDQAAVEAWGYGHEGDLARVQLADGEQDPTLIHWAVDGGQTGLGYAAYLSDIQELRPGPDASAGEYAG
WASQVLETHGAFQLLAALRRGPYGVEALNERLAAALRQRGLIRGEGAWYEGRPVIVTRNDYGLGLINGDIGIALRVPRFL
VQSPEAGGAGEERQKVLRVAFRAADGSGRIRWVPPHRLESVETAFALTVHKAQGSEFRHAALLLPDRPSPVLTRELLYTG
ITRASQWFTLLEPQPAVLKAAVRQRTVRGGGLRAMLEAAG

Sequences:

>Translated_680_residues
MSVRVDQEAILRWLREAEALGWLRPLDGALAEFLREQVPDAPPLLLLAAALTSHQAGRGHVCLDLDQLWERAEPVLSLPP
ETVDAPEPVKSPAALLDAAGGRDAFERQLECPELVGRGPGSTPLVRDGPRLYLRRYWACERTIARVVQQRVDAAAQWRAQ
LDPATVRRWLDGLFGAPGGDGPDWQRVACAVAAGSGFSVITGGPGTGKTTTVLRLLALLQGLHGGALRIRLTAPTGKAAA
RLNASIAGAVDRLGLEELDGGAELRARIPTEVVTVHRLLGAGGGRRFRHHAGEPLAADVVVVDEASMIDVELMAALLEAL
PDGGRLVLLGDKDQLASVEAGAILGELCARADQGGYWPDTAEWLEAVSGQCIPSALIDPTGGGLDQHVVMLRHSHRFGAD
SGIGRLARAVNAGDQAAVEAWGYGHEGDLARVQLADGEQDPTLIHWAVDGGQTGLGYAAYLSDIQELRPGPDASAGEYAG
WASQVLETHGAFQLLAALRRGPYGVEALNERLAAALRQRGLIRGEGAWYEGRPVIVTRNDYGLGLINGDIGIALRVPRFL
VQSPEAGGAGEERQKVLRVAFRAADGSGRIRWVPPHRLESVETAFALTVHKAQGSEFRHAALLLPDRPSPVLTRELLYTG
ITRASQWFTLLEPQPAVLKAAVRQRTVRGGGLRAMLEAAG
>Mature_679_residues
SVRVDQEAILRWLREAEALGWLRPLDGALAEFLREQVPDAPPLLLLAAALTSHQAGRGHVCLDLDQLWERAEPVLSLPPE
TVDAPEPVKSPAALLDAAGGRDAFERQLECPELVGRGPGSTPLVRDGPRLYLRRYWACERTIARVVQQRVDAAAQWRAQL
DPATVRRWLDGLFGAPGGDGPDWQRVACAVAAGSGFSVITGGPGTGKTTTVLRLLALLQGLHGGALRIRLTAPTGKAAAR
LNASIAGAVDRLGLEELDGGAELRARIPTEVVTVHRLLGAGGGRRFRHHAGEPLAADVVVVDEASMIDVELMAALLEALP
DGGRLVLLGDKDQLASVEAGAILGELCARADQGGYWPDTAEWLEAVSGQCIPSALIDPTGGGLDQHVVMLRHSHRFGADS
GIGRLARAVNAGDQAAVEAWGYGHEGDLARVQLADGEQDPTLIHWAVDGGQTGLGYAAYLSDIQELRPGPDASAGEYAGW
ASQVLETHGAFQLLAALRRGPYGVEALNERLAAALRQRGLIRGEGAWYEGRPVIVTRNDYGLGLINGDIGIALRVPRFLV
QSPEAGGAGEERQKVLRVAFRAADGSGRIRWVPPHRLESVETAFALTVHKAQGSEFRHAALLLPDRPSPVLTRELLYTGI
TRASQWFTLLEPQPAVLKAAVRQRTVRGGGLRAMLEAAG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=671, Percent_Identity=42.4739195230999, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 72507; Mature: 72376

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVDQEAILRWLREAEALGWLRPLDGALAEFLREQVPDAPPLLLLAAALTSHQAGRGH
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
VCLDLDQLWERAEPVLSLPPETVDAPEPVKSPAALLDAAGGRDAFERQLECPELVGRGPG
EEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCHHHHCCCCC
STPLVRDGPRLYLRRYWACERTIARVVQQRVDAAAQWRAQLDPATVRRWLDGLFGAPGGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
GPDWQRVACAVAAGSGFSVITGGPGTGKTTTVLRLLALLQGLHGGALRIRLTAPTGKAAA
CCCHHHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
RLNASIAGAVDRLGLEELDGGAELRARIPTEVVTVHRLLGAGGGRRFRHHAGEPLAADVV
HHCCHHHHHHHHCCHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
VVDEASMIDVELMAALLEALPDGGRLVLLGDKDQLASVEAGAILGELCARADQGGYWPDT
EECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AEWLEAVSGQCIPSALIDPTGGGLDQHVVMLRHSHRFGADSGIGRLARAVNAGDQAAVEA
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHH
WGYGHEGDLARVQLADGEQDPTLIHWAVDGGQTGLGYAAYLSDIQELRPGPDASAGEYAG
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
WASQVLETHGAFQLLAALRRGPYGVEALNERLAAALRQRGLIRGEGAWYEGRPVIVTRND
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECC
YGLGLINGDIGIALRVPRFLVQSPEAGGAGEERQKVLRVAFRAADGSGRIRWVPPHRLES
CCEEEEECCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHH
VETAFALTVHKAQGSEFRHAALLLPDRPSPVLTRELLYTGITRASQWFTLLEPQPAVLKA
HHHHHEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCHHHHHH
AVRQRTVRGGGLRAMLEAAG
HHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
SVRVDQEAILRWLREAEALGWLRPLDGALAEFLREQVPDAPPLLLLAAALTSHQAGRGH
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
VCLDLDQLWERAEPVLSLPPETVDAPEPVKSPAALLDAAGGRDAFERQLECPELVGRGPG
EEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCHHHHCCCCC
STPLVRDGPRLYLRRYWACERTIARVVQQRVDAAAQWRAQLDPATVRRWLDGLFGAPGGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
GPDWQRVACAVAAGSGFSVITGGPGTGKTTTVLRLLALLQGLHGGALRIRLTAPTGKAAA
CCCHHHHEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
RLNASIAGAVDRLGLEELDGGAELRARIPTEVVTVHRLLGAGGGRRFRHHAGEPLAADVV
HHCCHHHHHHHHCCHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
VVDEASMIDVELMAALLEALPDGGRLVLLGDKDQLASVEAGAILGELCARADQGGYWPDT
EECCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AEWLEAVSGQCIPSALIDPTGGGLDQHVVMLRHSHRFGADSGIGRLARAVNAGDQAAVEA
HHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHH
WGYGHEGDLARVQLADGEQDPTLIHWAVDGGQTGLGYAAYLSDIQELRPGPDASAGEYAG
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
WASQVLETHGAFQLLAALRRGPYGVEALNERLAAALRQRGLIRGEGAWYEGRPVIVTRND
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECC
YGLGLINGDIGIALRVPRFLVQSPEAGGAGEERQKVLRVAFRAADGSGRIRWVPPHRLES
CCEEEEECCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHH
VETAFALTVHKAQGSEFRHAALLLPDRPSPVLTRELLYTGITRASQWFTLLEPQPAVLKA
HHHHHEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCHHHHHH
AVRQRTVRGGGLRAMLEAAG
HHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]