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The map label for this gene is recG [H]

Identifier: 121997758

GI number: 121997758

Start: 1038190

End: 1040265

Strand: Reverse

Name: recG [H]

Synonym: Hhal_0967

Alternate gene names: 121997758

Gene position: 1040265-1038190 (Counterclockwise)

Preceding gene: 121997759

Following gene: 121997757

Centisome position: 38.84

GC content: 74.61

Gene sequence:

>2076_bases
GTGGACGGGGCACAGCGGCGGCTGACCAGCCTGCCGGGCGTCGGGCCGCGCCTGGCCGAACGCCTGGCACGGCTGGGCCT
GCACACGGTGGGCGACCTGCTGCTGCACCGCCCCATCCGCTACGAGGACCGCACCCGACTGCGGCCCATCGGCGGCCTGC
AGCCGGGCGAGCGGGTGCTGATCGAGGGGCGGGTGGAGTGGTCCGAGGTGGCACGGGGTCGGCGCAAGCGGCTGTTGTGC
CGGCTTAGCGACGGCACCGGGCAGCTTGATCTGGTCTTCTTCCACTTCCATCCGCGCCAGGCCGAGCGCCTCAGCCGCGG
CGTGGTGCTGCGCTGTTTCGGCGAGGTCCGGGCCGGCTACGGCGGCCTGCAAATGGCCCACCCGGAGCACCAGCGGGTGG
CCCCCGGGGACGCCGACGGCCCCGGCGAGGAGGCCCTGACCCCGGTCTATGCCAGCACCGACGGCCTTCACCAGGGGCAG
CTGCGCAAGCTGGTCGACGCCGCCCTGAGCCTCCTCCCCGGGGCGGCCCCGGAGTGCCTGCCCGATGCCGCTCGCGTGGA
TCCGCAGTGGCCGTCCCTGGCCGAGGCGCTGCGGACCGTCCACCGGCCGCCGCCGGAGGCCGACACCGAGACCCTGCTCG
CCGGCACCCATCCCGCGGTGCGCCGCGTGGCCTGCGAGGAGCTCCTCGCCCACCACCTGACCCTGCGTCGCCGGCGCCAG
GCGCTCCGCTCGGAGGCCGGCGCCCCGCCCTTGGACCAGGGCGAGGCGCTGGCCCAGCGTCTGCTGCAGAGCCTGCCCTT
CGCGCTGACGGGTGCCCAGCAGCGGGTGGATGGCGAGCTGGCTGAAGACATGGCCCGCTCGATGCCGATGCTGCGCCTGC
TCCAGGGCGACGTCGGCTCGGGTAAGACCGTGGTGGCGGCTCTGGCCTGCGCGCGCGCCGTCGGCAGTGGCTACCAGGCG
GCGCTGATGGCGCCCACCGAGCTGCTCGCCGAGCAGCACTGCCGCAGCCTGCAGGGCTGGTTCCAGCCGCTGGGCGTGGA
GGTCGCCTGGCTCTCCGGGGGTGCCCCGGCGGCCGAGCGCCGGGCGGCGCGTCAGCGCCTGGCCGAGGGGCGGGCCGGGA
TCGCCGTGGGCACCCACGCGCTGTTCCAGGAGGAGGTGCAGTTCCGCCGCCTGGGGCTGGTGGTGGTGGACGAGCAGCAC
CGCTTCGGGGTGCACCAGCGCCTGGCGCTCAAGGACAAGGGCGGTGGCGCCGAGCCGCATCAGCTGACCATGACCGCCAC
CCCCATCCCCCGGACGTTGGCCATGACCGCCTACGCCGACCTGGACGTCTCCTCGCTCGACGAGCGCCCCCCCGGGCGGA
CCCCGGTGAAGACGGTGGTGGTGGCCGAGCGGCGCCGCGCCGAGGTCATCGCGCGCATCCGCGCCGCCCTCGACGAGGGC
CGCCAGGCGTACTGGGTCTGCACCCTGATCGAGGCCTCGGACGAACTCGAGGCCCAGGCTGCCGAGGATACCGCCGCGGA
ACTCGATCGGGCGGTGGGCGATGCCCACCGGGTGGCCCTGGTCCACGGCCGCATGTCCCCCGCGGAGAAGGAGCGCACCA
TGGCGGCCTTCGCCCAGGGCGAGGTGGCGCTGCTGGTGGCCACCACGGTGATCGAGGTGGGGGTCGACGTGCCTAACGCC
AGTCTCATGGTCATCGATAACGCCGAGCGCCTCGGCCTGGCCCAGCTCCATCAGCTGCGCGGGCGGGTGGGCCGTGGTCG
CGCGGCGTCGACTTGTGTGCTCATGTATCATGGGCCGCTGTCCGAGAGCGCCCGGCAGCGGCTCGCCGTGTTGCGAGAGA
CCGACGATGGGTTCGCCATCGCCCGGCGGGATCTGGACATCCGCGGCCCCGGGGAGCTGCTGGGCACCCGGCAAACCGGG
GCGCTGAGCCTGCGCGTGGCCGACCTGCGCCGTGATGCGGACCTGCTGGAGGCGGTCCAGCAGGTGGGGGCCGAACTCCT
CGAGCAGGCCCCGGGGACCGCCGAGCAGCTGATCCGTCGGTGGGTCGGCGAGGCCGAGCGCTATGGGCAGGTGTGA

Upstream 100 bases:

>100_bases
CCCCTCGCGGGCAGCCATCGGCGTCGCCGCGTTGCCCAAGGGGGCCGCGGTGGAGATGGACGCCGTCCTCTATCTGCCCC
GGGAGGGCTGAAGCCCGGCC

Downstream 100 bases:

>100_bases
CCGGTTCCGCAATGACGGGTGATGGATTCGCAGTGGCAAACGGGGTGAGGGAACACGCCGCCTGGCAGCCCCAGGCAGCA
GCCTGGCGGCCCGGGGTGGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MDGAQRRLTSLPGVGPRLAERLARLGLHTVGDLLLHRPIRYEDRTRLRPIGGLQPGERVLIEGRVEWSEVARGRRKRLLC
RLSDGTGQLDLVFFHFHPRQAERLSRGVVLRCFGEVRAGYGGLQMAHPEHQRVAPGDADGPGEEALTPVYASTDGLHQGQ
LRKLVDAALSLLPGAAPECLPDAARVDPQWPSLAEALRTVHRPPPEADTETLLAGTHPAVRRVACEELLAHHLTLRRRRQ
ALRSEAGAPPLDQGEALAQRLLQSLPFALTGAQQRVDGELAEDMARSMPMLRLLQGDVGSGKTVVAALACARAVGSGYQA
ALMAPTELLAEQHCRSLQGWFQPLGVEVAWLSGGAPAAERRAARQRLAEGRAGIAVGTHALFQEEVQFRRLGLVVVDEQH
RFGVHQRLALKDKGGGAEPHQLTMTATPIPRTLAMTAYADLDVSSLDERPPGRTPVKTVVVAERRRAEVIARIRAALDEG
RQAYWVCTLIEASDELEAQAAEDTAAELDRAVGDAHRVALVHGRMSPAEKERTMAAFAQGEVALLVATTVIEVGVDVPNA
SLMVIDNAERLGLAQLHQLRGRVGRGRAASTCVLMYHGPLSESARQRLAVLRETDDGFAIARRDLDIRGPGELLGTRQTG
ALSLRVADLRRDADLLEAVQQVGAELLEQAPGTAEQLIRRWVGEAERYGQV

Sequences:

>Translated_691_residues
MDGAQRRLTSLPGVGPRLAERLARLGLHTVGDLLLHRPIRYEDRTRLRPIGGLQPGERVLIEGRVEWSEVARGRRKRLLC
RLSDGTGQLDLVFFHFHPRQAERLSRGVVLRCFGEVRAGYGGLQMAHPEHQRVAPGDADGPGEEALTPVYASTDGLHQGQ
LRKLVDAALSLLPGAAPECLPDAARVDPQWPSLAEALRTVHRPPPEADTETLLAGTHPAVRRVACEELLAHHLTLRRRRQ
ALRSEAGAPPLDQGEALAQRLLQSLPFALTGAQQRVDGELAEDMARSMPMLRLLQGDVGSGKTVVAALACARAVGSGYQA
ALMAPTELLAEQHCRSLQGWFQPLGVEVAWLSGGAPAAERRAARQRLAEGRAGIAVGTHALFQEEVQFRRLGLVVVDEQH
RFGVHQRLALKDKGGGAEPHQLTMTATPIPRTLAMTAYADLDVSSLDERPPGRTPVKTVVVAERRRAEVIARIRAALDEG
RQAYWVCTLIEASDELEAQAAEDTAAELDRAVGDAHRVALVHGRMSPAEKERTMAAFAQGEVALLVATTVIEVGVDVPNA
SLMVIDNAERLGLAQLHQLRGRVGRGRAASTCVLMYHGPLSESARQRLAVLRETDDGFAIARRDLDIRGPGELLGTRQTG
ALSLRVADLRRDADLLEAVQQVGAELLEQAPGTAEQLIRRWVGEAERYGQV
>Mature_691_residues
MDGAQRRLTSLPGVGPRLAERLARLGLHTVGDLLLHRPIRYEDRTRLRPIGGLQPGERVLIEGRVEWSEVARGRRKRLLC
RLSDGTGQLDLVFFHFHPRQAERLSRGVVLRCFGEVRAGYGGLQMAHPEHQRVAPGDADGPGEEALTPVYASTDGLHQGQ
LRKLVDAALSLLPGAAPECLPDAARVDPQWPSLAEALRTVHRPPPEADTETLLAGTHPAVRRVACEELLAHHLTLRRRRQ
ALRSEAGAPPLDQGEALAQRLLQSLPFALTGAQQRVDGELAEDMARSMPMLRLLQGDVGSGKTVVAALACARAVGSGYQA
ALMAPTELLAEQHCRSLQGWFQPLGVEVAWLSGGAPAAERRAARQRLAEGRAGIAVGTHALFQEEVQFRRLGLVVVDEQH
RFGVHQRLALKDKGGGAEPHQLTMTATPIPRTLAMTAYADLDVSSLDERPPGRTPVKTVVVAERRRAEVIARIRAALDEG
RQAYWVCTLIEASDELEAQAAEDTAAELDRAVGDAHRVALVHGRMSPAEKERTMAAFAQGEVALLVATTVIEVGVDVPNA
SLMVIDNAERLGLAQLHQLRGRVGRGRAASTCVLMYHGPLSESARQRLAVLRETDDGFAIARRDLDIRGPGELLGTRQTG
ALSLRVADLRRDADLLEAVQQVGAELLEQAPGTAEQLIRRWVGEAERYGQV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=55.8610709117221, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=412, Percent_Identity=38.3495145631068, Blast_Score=233, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75049; Mature: 75049

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGAQRRLTSLPGVGPRLAERLARLGLHTVGDLLLHRPIRYEDRTRLRPIGGLQPGERVL
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
IEGRVEWSEVARGRRKRLLCRLSDGTGQLDLVFFHFHPRQAERLSRGVVLRCFGEVRAGY
EECCCCHHHHHCCHHHEEEEEECCCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHCCC
GGLQMAHPEHQRVAPGDADGPGEEALTPVYASTDGLHQGQLRKLVDAALSLLPGAAPECL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHC
PDAARVDPQWPSLAEALRTVHRPPPEADTETLLAGTHPAVRRVACEELLAHHLTLRRRRQ
CCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRSEAGAPPLDQGEALAQRLLQSLPFALTGAQQRVDGELAEDMARSMPMLRLLQGDVGS
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHCCCCCC
GKTVVAALACARAVGSGYQAALMAPTELLAEQHCRSLQGWFQPLGVEVAWLSGGAPAAER
CHHHHHHHHHHHHHCCCCCEEHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
RAARQRLAEGRAGIAVGTHALFQEEVQFRRLGLVVVDEQHRFGVHQRLALKDKGGGAEPH
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEECCHHHCCHHHHEEEECCCCCCCCC
QLTMTATPIPRTLAMTAYADLDVSSLDERPPGRTPVKTVVVAERRRAEVIARIRAALDEG
EEEEECCCCCHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RQAYWVCTLIEASDELEAQAAEDTAAELDRAVGDAHRVALVHGRMSPAEKERTMAAFAQG
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHCC
EVALLVATTVIEVGVDVPNASLMVIDNAERLGLAQLHQLRGRVGRGRAASTCVLMYHGPL
CEEEHHHHHHHHHCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCC
SESARQRLAVLRETDDGFAIARRDLDIRGPGELLGTRQTGALSLRVADLRRDADLLEAVQ
CHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHCCCCCCCEEEEEHHHHHCCHHHHHHHH
QVGAELLEQAPGTAEQLIRRWVGEAERYGQV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDGAQRRLTSLPGVGPRLAERLARLGLHTVGDLLLHRPIRYEDRTRLRPIGGLQPGERVL
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
IEGRVEWSEVARGRRKRLLCRLSDGTGQLDLVFFHFHPRQAERLSRGVVLRCFGEVRAGY
EECCCCHHHHHCCHHHEEEEEECCCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHCCC
GGLQMAHPEHQRVAPGDADGPGEEALTPVYASTDGLHQGQLRKLVDAALSLLPGAAPECL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHC
PDAARVDPQWPSLAEALRTVHRPPPEADTETLLAGTHPAVRRVACEELLAHHLTLRRRRQ
CCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRSEAGAPPLDQGEALAQRLLQSLPFALTGAQQRVDGELAEDMARSMPMLRLLQGDVGS
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHCCCCCC
GKTVVAALACARAVGSGYQAALMAPTELLAEQHCRSLQGWFQPLGVEVAWLSGGAPAAER
CHHHHHHHHHHHHHCCCCCEEHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
RAARQRLAEGRAGIAVGTHALFQEEVQFRRLGLVVVDEQHRFGVHQRLALKDKGGGAEPH
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEECCHHHCCHHHHEEEECCCCCCCCC
QLTMTATPIPRTLAMTAYADLDVSSLDERPPGRTPVKTVVVAERRRAEVIARIRAALDEG
EEEEECCCCCHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RQAYWVCTLIEASDELEAQAAEDTAAELDRAVGDAHRVALVHGRMSPAEKERTMAAFAQG
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHCC
EVALLVATTVIEVGVDVPNASLMVIDNAERLGLAQLHQLRGRVGRGRAASTCVLMYHGPL
CEEEHHHHHHHHHCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCC
SESARQRLAVLRETDDGFAIARRDLDIRGPGELLGTRQTGALSLRVADLRRDADLLEAVQ
CHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHCCCCCCCEEEEEHHHHHCCHHHHHHHH
QVGAELLEQAPGTAEQLIRRWVGEAERYGQV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]