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The map label for this gene is ubiA

Identifier: 121997756

GI number: 121997756

Start: 1036693

End: 1037592

Strand: Reverse

Name: ubiA

Synonym: Hhal_0965

Alternate gene names: 121997756

Gene position: 1037592-1036693 (Counterclockwise)

Preceding gene: 121997757

Following gene: 121997754

Centisome position: 38.74

GC content: 68.0

Gene sequence:

>900_bases
GTGAGCGGTGAGGTGCATAGCGGGGAGCCATCCGGCCCGGGTCGGGTTGGCGAGCGCTTGCGGACTTATGCACAGCTGGC
GCGGCTCGACCGGCCCATCGGCAACTTCCTGCTGCTCTGGCCGGTGCTCTGGGCGCTGTGGATCGCGGCGGCCGGCGTGC
CCGATCTGGATCTGCTGGTCATCTTTACCCTCGGGGTGGTGGTCATGCGGGCCGCTGGCTGCGTCATCAACGACTTCGCC
GATCGCCACATCGACGGCCACGTCAAGCGCACCCGGCAGCGGCCCTTCGCCACCGGCCGGGTCTCCGAGCGCGAGGCGCT
GCTCCTGTTCGTGGTCCTCTGCCTGCTCGCCTTCGGTCTGGTCCTGCTGACCAACCCGCTGACCATCCTGATGTCCCTGG
TGGCCGTGGTGCTGGCGGCCACCTACCCCTTCACCAAGCGCTACACCCACCTGCCCCAGGTCCACCTGGGGCTGGCCTTC
GGCTGGGCCGTGCCCATGGTCTTTGCCGCGCAGACCGGAACGGTGCCGGTGGTGGCGTGGCTGCTGCTGATCGCCACCGT
GCTCTGGGCCACCGTCTACGACACCATGTACGCCATGGTCGATCGGGACGACGACATCAAGATCGGCGTCAAGTCCACGG
CCGTGCTCTTCGGTGACCTGGACCGGCTGATGATCGCTATCCTGCAGGGGCTGATGCTGCTGGCGATGGTGCAGGTCGGC
CTGCACGTGGAGGCCAGCACGGCCTATTACCTGGGATTGGCCGGGGCCGCCGGCCTGTTCGCCTATCAGCAGTACCTGAT
CCGACGCCGCGAGCGCCAGGACTGCTTCCGTGCCTTCCTCAACAACGCCTGGCTCGGCGGCGTGGTCTTCGCTGGCCTGG
CGGCCGATCTCCACCTCTAG

Upstream 100 bases:

>100_bases
CTGCCATCGCCGGCCGGGGGCTGGGCGCGGCGCTCGACGCTGTCCGTGGCCGGACGGCGGCTGCTGGTAACCGAAGTCTT
TTTCCCGGAGGGTGTTGAGG

Downstream 100 bases:

>100_bases
ACGCACCGGCTACGGGGTCCGCGCCACCGCCCACAGATCGACCCGGCCGACCCCGGCGTCGCGCAGGGCCTGCGCCGCCT
CCTCGGCGGTCGCCCCGGTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSGEVHSGEPSGPGRVGERLRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLVIFTLGVVVMRAAGCVINDFA
DRHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGLVLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAF
GWAVPMVFAAQTGTVPVVAWLLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVG
LHVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL

Sequences:

>Translated_299_residues
MSGEVHSGEPSGPGRVGERLRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLVIFTLGVVVMRAAGCVINDFA
DRHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGLVLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAF
GWAVPMVFAAQTGTVPVVAWLLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVG
LHVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL
>Mature_298_residues
SGEVHSGEPSGPGRVGERLRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLVIFTLGVVVMRAAGCVINDFAD
RHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGLVLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAFG
WAVPMVFAAQTGTVPVVAWLLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVGL
HVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=35.7400722021661, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=56.6787003610108, Blast_Score=306, Evalue=7e-85,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=34.7517730496454, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=34.1637010676157, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17553720, Length=340, Percent_Identity=28.8235294117647, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=38.2978723404255, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=137, Percent_Identity=37.956204379562, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=281, Percent_Identity=32.0284697508897, Blast_Score=148, Evalue=9e-37,
Organism=Drosophila melanogaster, GI21355567, Length=278, Percent_Identity=38.1294964028777, Blast_Score=191, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32817; Mature: 32686

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEVHSGEPSGPGRVGERLRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IFTLGVVVMRAAGCVINDFADRHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGL
HHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAFGWAVPMVFAAQTGTVPVVAW
HHHHCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVG
HHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGEVHSGEPSGPGRVGERLRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IFTLGVVVMRAAGCVINDFADRHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGL
HHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAFGWAVPMVFAAQTGTVPVVAW
HHHHCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVG
HHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA