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The map label for this gene is hflX [H]

Identifier: 121997462

GI number: 121997462

Start: 747574

End: 748911

Strand: Reverse

Name: hflX [H]

Synonym: Hhal_0665

Alternate gene names: 121997462

Gene position: 748911-747574 (Counterclockwise)

Preceding gene: 121997463

Following gene: 121997461

Centisome position: 27.96

GC content: 70.33

Gene sequence:

>1338_bases
TTGTCGGCGAGGAGGAGAGCAATAACTGAACAGCGCATCGGTAGCGGTCCGGCGGACCTGTTCGCCCGGCCATCCGGCGG
TGAGCGGGCCGTGGTTCTGCATGTCCGGCTTCCCGGCGACGCCCTCGACGCCGCGGAAGAGTTTGAGGCGCTGGGTGACT
CGGCCGGGGCCGAGGTGGTGGGCCGCTTCCGGCATCGTCGCGACACCCCGGACCCGCGCACCTTCATCGGCCGCGGCAAG
GTGGCCGAACTGGCCGATTGGGTGCGCGAGCTGGAGGCTGCCCTGGTGCTGGTGGATCAGCCCCTGTCCGCCGCTCAGGA
GCGCAACCTGGAGACCGACCTGGGCTGCCGGGTCCTCGACCGCACCGGTCTGATCTTGGATATCTTCGCCCAGCGGGCGC
GGACCTTCGAAGGCCGGCTCCAGGTGGAACTGGCCCAGCTCAAGCACGTTGCCAGCCGCCTGGTGCGTGGCTGGTCCCAC
CTGGAGCGGCAGAAGGGCGGCATCGGTCTGCGCGGCCCGGGCGAGAAGCAGCTGGAGATGGACCGCCGGCTGATCGGCGG
ACGCATCCAGCAGATTGAGCGGCGCCTGGCCAAGGTGCGCCGCACGCGCGAACAGGGCCGCAAGGCGCGGCGCAAGCGCG
AGCTGCCCGTGGTCTCGCTGGTCGGCTACACCAACGCCGGCAAGTCCACGTTGTTCAACCACGTCACCGGCTCGCAGCGC
CGGGCCGAGGATCGGCTGTTCGCCACCCTCGACCCGTCCTGGCGCCGCGTGGATCTGGCCCGCGGCTCAGCGGCGGTGGT
CTCGGATACCGTGGGCTTCATCAGCCGGTTGCCCCACGACCTCGTGGCCGCCTTTCGTTCCACCCTCGAAGAGGTGACCG
ACGCCGATCTGCTCCTGCACGTCATCGATGCCGGGGCCGAGGAGCGTGAGCACCAGATCGAGCAGGTGGAGGCGGTCCTC
GCCGAACTCGGCGCTGACGCAGTGCCCACCCTGCGCGTCTACAACAAGGTGGATACCTGCGCCCTTGCGCCGGGACGGAT
CGAGGATGACGAGGGCCTGGTGACCGGCGTCCGGATCTCCGCGGCGACCGGCGAAGGGGTCGAGACCCTGCTGGAGGCCG
TGGCCGAGCGACTCGGCCCGGAGCGCATCCGTCGCCGAGTGCACCTGCGGCCGGACCAGGGGCGCTTGCGCGCCCAGCTG
TTCCGGCTGGGGTGTGTCATCGAAGAGCACTGCGCCGAGGATGGCCAGCTTGCCCTGGAGGTGGAGCTCCCCGTACACGA
GCTGGAACGGCTCCATGTACGCGAGGGGCTCCCGCGTGGAGAGGTTGTCCCGGCCTGA

Upstream 100 bases:

>100_bases
AACGTGAACCAGATGGTGTACAAGCACGCCATCTCGACCATCGTCCCGGCACGGCGCGTGCGCCTGCCGCAGCAGGGCGA
AGAGGCATCCGCCGAATCGA

Downstream 100 bases:

>100_bases
CTTCGGTTGCGGTTGGCGGGGCAGCTCCCTAGAATCGGACCGTTCGATCGACGGCAGATCGTCTTAGTCACATACGGAGT
CCTGAATGGCGTGGAATGAG

Product: GTP-binding protein, HSR1-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSARRRAITEQRIGSGPADLFARPSGGERAVVLHVRLPGDALDAAEEFEALGDSAGAEVVGRFRHRRDTPDPRTFIGRGK
VAELADWVRELEAALVLVDQPLSAAQERNLETDLGCRVLDRTGLILDIFAQRARTFEGRLQVELAQLKHVASRLVRGWSH
LERQKGGIGLRGPGEKQLEMDRRLIGGRIQQIERRLAKVRRTREQGRKARRKRELPVVSLVGYTNAGKSTLFNHVTGSQR
RAEDRLFATLDPSWRRVDLARGSAAVVSDTVGFISRLPHDLVAAFRSTLEEVTDADLLLHVIDAGAEEREHQIEQVEAVL
AELGADAVPTLRVYNKVDTCALAPGRIEDDEGLVTGVRISAATGEGVETLLEAVAERLGPERIRRRVHLRPDQGRLRAQL
FRLGCVIEEHCAEDGQLALEVELPVHELERLHVREGLPRGEVVPA

Sequences:

>Translated_445_residues
MSARRRAITEQRIGSGPADLFARPSGGERAVVLHVRLPGDALDAAEEFEALGDSAGAEVVGRFRHRRDTPDPRTFIGRGK
VAELADWVRELEAALVLVDQPLSAAQERNLETDLGCRVLDRTGLILDIFAQRARTFEGRLQVELAQLKHVASRLVRGWSH
LERQKGGIGLRGPGEKQLEMDRRLIGGRIQQIERRLAKVRRTREQGRKARRKRELPVVSLVGYTNAGKSTLFNHVTGSQR
RAEDRLFATLDPSWRRVDLARGSAAVVSDTVGFISRLPHDLVAAFRSTLEEVTDADLLLHVIDAGAEEREHQIEQVEAVL
AELGADAVPTLRVYNKVDTCALAPGRIEDDEGLVTGVRISAATGEGVETLLEAVAERLGPERIRRRVHLRPDQGRLRAQL
FRLGCVIEEHCAEDGQLALEVELPVHELERLHVREGLPRGEVVPA
>Mature_444_residues
SARRRAITEQRIGSGPADLFARPSGGERAVVLHVRLPGDALDAAEEFEALGDSAGAEVVGRFRHRRDTPDPRTFIGRGKV
AELADWVRELEAALVLVDQPLSAAQERNLETDLGCRVLDRTGLILDIFAQRARTFEGRLQVELAQLKHVASRLVRGWSHL
ERQKGGIGLRGPGEKQLEMDRRLIGGRIQQIERRLAKVRRTREQGRKARRKRELPVVSLVGYTNAGKSTLFNHVTGSQRR
AEDRLFATLDPSWRRVDLARGSAAVVSDTVGFISRLPHDLVAAFRSTLEEVTDADLLLHVIDAGAEEREHQIEQVEAVLA
ELGADAVPTLRVYNKVDTCALAPGRIEDDEGLVTGVRISAATGEGVETLLEAVAERLGPERIRRRVHLRPDQGRLRAQLF
RLGCVIEEHCAEDGQLALEVELPVHELERLHVREGLPRGEVVPA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=224, Percent_Identity=37.5, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310133116, Length=223, Percent_Identity=37.219730941704, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=38.2352941176471, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=38.2352941176471, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=38.2352941176471, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=38.2352941176471, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1790615, Length=418, Percent_Identity=52.3923444976077, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17561038, Length=344, Percent_Identity=29.3604651162791, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=30.5949008498584, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49321; Mature: 49190

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRRAITEQRIGSGPADLFARPSGGERAVVLHVRLPGDALDAAEEFEALGDSAGAEVV
CCCHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHH
GRFRHRRDTPDPRTFIGRGKVAELADWVRELEAALVLVDQPLSAAQERNLETDLGCRVLD
HHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHCCEECC
RTGLILDIFAQRARTFEGRLQVELAQLKHVASRLVRGWSHLERQKGGIGLRGPGEKQLEM
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRRLIGGRIQQIERRLAKVRRTREQGRKARRKRELPVVSLVGYTNAGKSTLFNHVTGSQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCHH
RAEDRLFATLDPSWRRVDLARGSAAVVSDTVGFISRLPHDLVAAFRSTLEEVTDADLLLH
HHHHCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VIDAGAEEREHQIEQVEAVLAELGADAVPTLRVYNKVDTCALAPGRIEDDEGLVTGVRIS
HHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHCCCCCCCCCCCCCEEEEEEE
AATGEGVETLLEAVAERLGPERIRRRVHLRPDQGRLRAQLFRLGCVIEEHCAEDGQLALE
CCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VELPVHELERLHVREGLPRGEVVPA
EECCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SARRRAITEQRIGSGPADLFARPSGGERAVVLHVRLPGDALDAAEEFEALGDSAGAEVV
CCHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHH
GRFRHRRDTPDPRTFIGRGKVAELADWVRELEAALVLVDQPLSAAQERNLETDLGCRVLD
HHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHCCEECC
RTGLILDIFAQRARTFEGRLQVELAQLKHVASRLVRGWSHLERQKGGIGLRGPGEKQLEM
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRRLIGGRIQQIERRLAKVRRTREQGRKARRKRELPVVSLVGYTNAGKSTLFNHVTGSQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCHH
RAEDRLFATLDPSWRRVDLARGSAAVVSDTVGFISRLPHDLVAAFRSTLEEVTDADLLLH
HHHHCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VIDAGAEEREHQIEQVEAVLAELGADAVPTLRVYNKVDTCALAPGRIEDDEGLVTGVRIS
HHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHCCCCCCCCCCCCCEEEEEEE
AATGEGVETLLEAVAERLGPERIRRRVHLRPDQGRLRAQLFRLGCVIEEHCAEDGQLALE
CCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VELPVHELERLHVREGLPRGEVVPA
EECCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]