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The map label for this gene is hfq

Identifier: 121997463

GI number: 121997463

Start: 748883

End: 749155

Strand: Reverse

Name: hfq

Synonym: Hhal_0666

Alternate gene names: 121997463

Gene position: 749155-748883 (Counterclockwise)

Preceding gene: 121997464

Following gene: 121997462

Centisome position: 27.97

GC content: 58.97

Gene sequence:

>273_bases
ATGGCGAAGGGGCAGTCACTGCAGGAACCCTTTCTCAATACGTTGCGCAAAGAGAAGGTCCCGGTCTCGATCTACCTGGT
CAACGGCATCAAGCTCCAGGGACAGATCGAATCCTTCGACCAGTTCGTGGTGCTGCTGCGCAACAACGTGAACCAGATGG
TGTACAAGCACGCCATCTCGACCATCGTCCCGGCACGGCGCGTGCGCCTGCCGCAGCAGGGCGAAGAGGCATCCGCCGAA
TCGATTGTCGGCGAGGAGGAGAGCAATAACTGA

Upstream 100 bases:

>100_bases
GGGCCCTCGGGGGCGTGTGATACACTCGTAGGCGTCGAGTAGCGCCCCTCCGGCGGGGTTCGCGGGTCCATAACAACAAC
AATCTTGGGGGCGATGCGCC

Downstream 100 bases:

>100_bases
ACAGCGCATCGGTAGCGGTCCGGCGGACCTGTTCGCCCGGCCATCCGGCGGTGAGCGGGCCGTGGTTCTGCATGTCCGGC
TTCCCGGCGACGCCCTCGAC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MAKGQSLQEPFLNTLRKEKVPVSIYLVNGIKLQGQIESFDQFVVLLRNNVNQMVYKHAISTIVPARRVRLPQQGEEASAE
SIVGEEESNN

Sequences:

>Translated_90_residues
MAKGQSLQEPFLNTLRKEKVPVSIYLVNGIKLQGQIESFDQFVVLLRNNVNQMVYKHAISTIVPARRVRLPQQGEEASAE
SIVGEEESNN
>Mature_89_residues
AKGQSLQEPFLNTLRKEKVPVSIYLVNGIKLQGQIESFDQFVVLLRNNVNQMVYKHAISTIVPARRVRLPQQGEEASAES
IVGEEESNN

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=68, Percent_Identity=83.8235294117647, Blast_Score=125, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_HALHL (A1WUT6)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002250.1
- ProteinModelPortal:   A1WUT6
- SMR:   A1WUT6
- STRING:   A1WUT6
- GeneID:   4710052
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0666
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   A1WUT6
- BioCyc:   HHAL349124:HHAL_0666-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 10125; Mature: 9994

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQEPFLNTLRKEKVPVSIYLVNGIKLQGQIESFDQFVVLLRNNVNQMVYKHAIS
CCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEECCHHHHHHHHHHHHHCHHHHHHHHHHH
TIVPARRVRLPQQGEEASAESIVGEEESNN
HHCCHHHCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
AKGQSLQEPFLNTLRKEKVPVSIYLVNGIKLQGQIESFDQFVVLLRNNVNQMVYKHAIS
CCCCCHHHHHHHHHHHCCCCEEEEEECCEEEECCHHHHHHHHHHHHHCHHHHHHHHHHH
TIVPARRVRLPQQGEEASAESIVGEEESNN
HHCCHHHCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA