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The map label for this gene is tig

Identifier: 121997405

GI number: 121997405

Start: 683151

End: 684461

Strand: Reverse

Name: tig

Synonym: Hhal_0604

Alternate gene names: 121997405

Gene position: 684461-683151 (Counterclockwise)

Preceding gene: 121997408

Following gene: 121997404

Centisome position: 25.55

GC content: 67.2

Gene sequence:

>1311_bases
ATGCAAGTTTCCGTGGAGACGACCGAAGGCCTGGGCCGCCGCATGACGGTCCAGGTCCCCGCCGAGCGCGTGGAGAACGA
GGTAGAACGCCGGCTGAAGGACCTCAGTGGCCGCGTTAAGATGGACGGCTTCCGCCCTGGCAAGGTGCCGGTCAAGGTCG
TTCGCAAGCAGTACGGCGCACAGGTGCGTAGCGAGGTGCTCAGCGAGGTGGTCCAGCAGACCTACTCCGAGGCCCTGGAG
CAGGAGTCCCTGCGCCCGGCCGGTAACCCGCATATCGAGCCCAAGCGCACCGGCGAAGGGGAAGACCTGGAGTACGAGGC
CTCCTTCGATGTGCTGCCCGAGATTGAGGTCGCGGGGCTGGACCAGATCCAGGTCGAGCGGCCCCAGGTCGAGATCACCG
ACGCCGACCTGGACAACGTCCTCGAGCGCCTGCGCAAGCAGCACGCCGATTACCAGGAGGTGGATCGGGCGGCCCAGGAC
GAGGACCGCGTGGTGATCGACTTCCACGGCACCATCGACGGCGAGGCGTTCACCGGCAACTCCGCCGAGGATGCGCCGCT
GATCCTCGGTGCCGGGCAGTTGCCCGAGGCCTTCGAGCAGGGGCTGCAGGGGGCGAAGGCCGGCCAGGAGCTGACGGTCG
AGCACAAGTTCCCGGACGAGCTCGCCGAGCCGAGCATCGCCGGCAAGACCGCCGTCTTCCAGGTGACGGTCAAGCGAGTG
GAAGAGCCGCAGCTGCCGGAGCTGGATGACGACTTTGCGGCTCGCCTGGGTATCCAGGAAGGGGGCGTCGAGGCGCTGCG
CGAGGCCGTGCGTGGCAACCTCGAGCGCGAGCGGCATCAGGCCGTGCGTCAGCGTCTCAAGCGACAGGTGCTCGATCAGC
TGGCCGATCAGAATGAGCTGGAGCTGCCCAAGAGCCTGATCGACGGCGAGATCCAGGCCCTGCGGCAACAGTCGGGCGCC
AGCGCCGAGGGCGAGCTGCCCGAGTCGGAGCGCTCGGCTTATGAAGACGTGGCGAGTCGCCGGGTCAAGCTGGGGCTGCT
GGTCAACGAGCTGGTGCGCAGCCAGGGCATCCAGCTCGATCGCGAGCGCATGATGACCCAGCTGCGTGAGATGGCTGCCA
ACTCCGGCCAGGATCCGAGCGAAGCGCTGCAGCAGATTGCCCAGGACCGGCAGATGATGCAGAGCCTGGAGGCCTCGGTC
ATCGAGGAGCAGGTGGTCGACTGGCTGCTCGAGCAGGTGCAGACCGAAGACAAGACGCTGAGCTTCGACGAGCTCATGAA
CAGCGAGGACGGCGACCAGGCTTCGGCCTGA

Upstream 100 bases:

>100_bases
TCTCTCCTTTCGCACCAAGCAATTCGTGGCCGCGACGGCATGGGCCGCGCGGTAGCGCGAAACCGCAACCACCAAACGTT
TGGATCCCAAGGACTTCCCG

Downstream 100 bases:

>100_bases
GTCGCGGCCCCGGGAGGCCAACGGCATGAGCGATACCCAGCAATCCGCCCCCGACATTTTCAACACCGGCCTGGTGCCGA
TGGTGGTCGAGCAGTCGGCG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGAQVRSEVLSEVVQQTYSEALE
QESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGLDQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQD
EDRVVIDFHGTIDGEAFTGNSAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRV
EEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNELELPKSLIDGEIQALRQQSGA
SAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLDRERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASV
IEEQVVDWLLEQVQTEDKTLSFDELMNSEDGDQASA

Sequences:

>Translated_436_residues
MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGAQVRSEVLSEVVQQTYSEALE
QESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGLDQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQD
EDRVVIDFHGTIDGEAFTGNSAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRV
EEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNELELPKSLIDGEIQALRQQSGA
SAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLDRERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASV
IEEQVVDWLLEQVQTEDKTLSFDELMNSEDGDQASA
>Mature_436_residues
MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGAQVRSEVLSEVVQQTYSEALE
QESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGLDQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQD
EDRVVIDFHGTIDGEAFTGNSAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRV
EEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNELELPKSLIDGEIQALRQQSGA
SAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLDRERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASV
IEEQVVDWLLEQVQTEDKTLSFDELMNSEDGDQASA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=433, Percent_Identity=41.8013856812933, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_HALHL (A1WUM8)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002192.1
- ProteinModelPortal:   A1WUM8
- SMR:   A1WUM8
- STRING:   A1WUM8
- GeneID:   4711551
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0604
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- PhylomeDB:   A1WUM8
- ProtClustDB:   PRK01490
- BioCyc:   HHAL349124:HHAL_0604-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 48679; Mature: 48679

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGA
CEEECCCHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHH
QVRSEVLSEVVQQTYSEALEQESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
DQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQDEDRVVIDFHGTIDGEAFTGN
CCEEECCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
SAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRV
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCCCCHHHHHHHHHHC
EEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNEL
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELPKSLIDGEIQALRQQSGASAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLD
HCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASVIEEQVVDWLLEQVQTEDKTL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SFDELMNSEDGDQASA
CHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGA
CEEECCCHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHH
QVRSEVLSEVVQQTYSEALEQESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
DQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQDEDRVVIDFHGTIDGEAFTGN
CCEEECCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
SAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRV
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCHHHCCCCCCCCHHHHHHHHHHC
EEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNEL
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELPKSLIDGEIQALRQQSGASAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLD
HCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASVIEEQVVDWLLEQVQTEDKTL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SFDELMNSEDGDQASA
CHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA