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The map label for this gene is ribB [H]

Identifier: 121611694

GI number: 121611694

Start: 5291599

End: 5292720

Strand: Direct

Name: ribB [H]

Synonym: Veis_4791

Alternate gene names: 121611694

Gene position: 5291599-5292720 (Clockwise)

Preceding gene: 121611693

Following gene: 121611695

Centisome position: 95.06

GC content: 69.16

Gene sequence:

>1122_bases
ATGACCTCTGTCCCCACTCCCGTGCCCATCTCGCCGGTGCAAGACATCGTCGCCGAGATGCGCGCCGGGCGCATCGTCAT
CCTGGTGGATGAGCAAGAGCGCGAAAACGAAGGCGACCTGGTGCTGGCCGCCGACCATGTCACGCCCGAGGCGATCAACT
TCATGGCGCGCTTCGGCCGCGGCCTGATCTGCCTGACGCTCACGCGCGAGCGCTGCGAGTTTCTCCACCTGCCGCCGATG
GCCGCGCGCAACGGCACGGTGTACAGCACGGCCTTCACGGTCTCCATCGAAGCGGCCGAAGGGGTGACCACCGGCATCTC
TGCGGCCGACCGCGCCCGCACCGTGCAGGTGGCCGTGGCCCCGGGCAGCCGGGCCAGCGATCTGGTGCAACCGGGCCATA
TCTTTCCGTTGCAGGCGGTCGATGGCGGCGTGCTGATGCGTGCCGGCCATACCGAGGCCGGCTGCGATCTGGCCGGCATG
GCCGGTTGCAGCCCGGCGGCGGTGATCTGCGAGATCATGAAGGACGACGGCACCATGGCCCGCCTGCCCGATCTGCAAGC
CTTCGCCGCCGGGCATGGCCTGAAGATCGGCACCATTGCCGACCTGATCGAGTACCGCAGCCGCAATGAATCGCTGGTGC
AAAAGGTGGGCAGCCGCGCACTGCAAACGGCCTACGGCGAGTTCACCGTCCACGCCTTTCGCGACCAGCCCAGCCAGGCC
GTGCACCTGGCGCTGGTCAAGGGGCAGTGGAGCGCCGACGAGGTGGTGCCGGTGCGCGTGCACGAGCCGCTGTCGGTGCT
CGACGCGCTCGGAGGCAACCGCTCCATGCACTCCTGGGATCTGAACACCGGCCTGCAATACCTGGCCGCCCAGGGCAAGG
GCGTGGCCGTGCTGCTCAACTGCGGCGAAAGCGCCGAGCAGTTGCTGGCCCAGTTCGAAGGCCGGGCGCGCGCCGCCCAG
GCCCCCGAACGCGGTCGCATGGATCTGCGCACCCACGGCGTGGGCGCGCAGATCCTGCGCGAATGCGGCGTGCACCGGAT
GGCGCTGATGGGCCAACCCCGGCGCATGCCGAGCATGGCCGGCTACGGGCTGGAGATCACCGGCTTCATCCCCAAGGAAT
GA

Upstream 100 bases:

>100_bases
CATGGGCCATCCCCCGGTGAACTAAAATCGCCCCTCCAAGGGCCGCCGACGCCCAGGCTCCTTTTGTGGCCTGCGCCAGC
GTTGCCGACGAAAGGCCTCC

Downstream 100 bases:

>100_bases
ACATGTTCGGCGCAGACAAAGGCACGGCAGACCGGCTCGACGGCAAGAAACTGCACATCGGCATCGTGCAAGCCCGCTTC
AACAGCGGCATCACCAACGC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTSVPTPVPISPVQDIVAEMRAGRIVILVDEQERENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCEFLHLPPM
AARNGTVYSTAFTVSIEAAEGVTTGISAADRARTVQVAVAPGSRASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAGM
AGCSPAAVICEIMKDDGTMARLPDLQAFAAGHGLKIGTIADLIEYRSRNESLVQKVGSRALQTAYGEFTVHAFRDQPSQA
VHLALVKGQWSADEVVPVRVHEPLSVLDALGGNRSMHSWDLNTGLQYLAAQGKGVAVLLNCGESAEQLLAQFEGRARAAQ
APERGRMDLRTHGVGAQILRECGVHRMALMGQPRRMPSMAGYGLEITGFIPKE

Sequences:

>Translated_373_residues
MTSVPTPVPISPVQDIVAEMRAGRIVILVDEQERENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCEFLHLPPM
AARNGTVYSTAFTVSIEAAEGVTTGISAADRARTVQVAVAPGSRASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAGM
AGCSPAAVICEIMKDDGTMARLPDLQAFAAGHGLKIGTIADLIEYRSRNESLVQKVGSRALQTAYGEFTVHAFRDQPSQA
VHLALVKGQWSADEVVPVRVHEPLSVLDALGGNRSMHSWDLNTGLQYLAAQGKGVAVLLNCGESAEQLLAQFEGRARAAQ
APERGRMDLRTHGVGAQILRECGVHRMALMGQPRRMPSMAGYGLEITGFIPKE
>Mature_372_residues
TSVPTPVPISPVQDIVAEMRAGRIVILVDEQERENEGDLVLAADHVTPEAINFMARFGRGLICLTLTRERCEFLHLPPMA
ARNGTVYSTAFTVSIEAAEGVTTGISAADRARTVQVAVAPGSRASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAGMA
GCSPAAVICEIMKDDGTMARLPDLQAFAAGHGLKIGTIADLIEYRSRNESLVQKVGSRALQTAYGEFTVHAFRDQPSQAV
HLALVKGQWSADEVVPVRVHEPLSVLDALGGNRSMHSWDLNTGLQYLAAQGKGVAVLLNCGESAEQLLAQFEGRARAAQA
PERGRMDLRTHGVGAQILRECGVHRMALMGQPRRMPSMAGYGLEITGFIPKE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=203, Percent_Identity=49.7536945812808, Blast_Score=208, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=39.6135265700483, Blast_Score=162, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 39848; Mature: 39717

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPTPVPISPVQDIVAEMRAGRIVILVDEQERENEGDLVLAADHVTPEAINFMARFGR
CCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GLICLTLTRERCEFLHLPPMAARNGTVYSTAFTVSIEAAEGVTTGISAADRARTVQVAVA
CEEEEEEEHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC
PGSRASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAGMAGCSPAAVICEIMKDDGTMA
CCCCHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
RLPDLQAFAAGHGLKIGTIADLIEYRSRNESLVQKVGSRALQTAYGEFTVHAFRDQPSQA
ECCCHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCE
VHLALVKGQWSADEVVPVRVHEPLSVLDALGGNRSMHSWDLNTGLQYLAAQGKGVAVLLN
EEEEEEECCCCCCCEEEEEECCHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCCEEEEEE
CGESAEQLLAQFEGRARAAQAPERGRMDLRTHGVGAQILRECGVHRMALMGQPRRMPSMA
CCCHHHHHHHHHCCCHHHCCCCCCCCCCEEECCCHHHHHHHCCCHHHHHCCCCCCCCCCC
GYGLEITGFIPKE
CCCEEEEECCCCC
>Mature Secondary Structure 
TSVPTPVPISPVQDIVAEMRAGRIVILVDEQERENEGDLVLAADHVTPEAINFMARFGR
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GLICLTLTRERCEFLHLPPMAARNGTVYSTAFTVSIEAAEGVTTGISAADRARTVQVAVA
CEEEEEEEHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC
PGSRASDLVQPGHIFPLQAVDGGVLMRAGHTEAGCDLAGMAGCSPAAVICEIMKDDGTMA
CCCCHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
RLPDLQAFAAGHGLKIGTIADLIEYRSRNESLVQKVGSRALQTAYGEFTVHAFRDQPSQA
ECCCHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCE
VHLALVKGQWSADEVVPVRVHEPLSVLDALGGNRSMHSWDLNTGLQYLAAQGKGVAVLLN
EEEEEEECCCCCCCEEEEEECCHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCCEEEEEE
CGESAEQLLAQFEGRARAAQAPERGRMDLRTHGVGAQILRECGVHRMALMGQPRRMPSMA
CCCHHHHHHHHHCCCHHHCCCCCCCCCCEEECCCHHHHHHHCCCHHHHHCCCCCCCCCCC
GYGLEITGFIPKE
CCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]