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The map label for this gene is hexR [C]

Identifier: 121611497

GI number: 121611497

Start: 5080965

End: 5081939

Strand: Direct

Name: hexR [C]

Synonym: Veis_4588

Alternate gene names: 121611497

Gene position: 5080965-5081939 (Clockwise)

Preceding gene: 121611492

Following gene: 121611498

Centisome position: 91.27

GC content: 70.87

Gene sequence:

>975_bases
ATGCGCACCAACGTCGACACCCCAGGCAGCACCGTGGCCCAGCGCATTGCGCAGGCGCTGCCGCGGCTGACGCGTTCGCA
CCGGCAGGTGGCCGACTTCGTGCTCGCGCATCCGTTGCAGGTCGCGACGCTGCCGATCGATGAACTGGCCGCTGCCGCGG
GCGTGTCGGTCGCCACGGCCAACCGCTTCGCGCGGGCACTGGACTTCGACGGCTACGCCACCTTCCGCGCCGAACTCGTG
CGCGGCTTCGAGTCGCTGGTGGCGCCGATCGAGCGGCTGCGCGGCAACCTGGAGCACCCCACCACGGTGGCCGAGGTGTT
CGCCACGGCGCTCGACGAGAGCCGCCGCAACATCGAAGCCACGCGACAGTCGCTCGACTACGCCGCCTGCGAGGCCGCGG
TGCAGCGCATCCTGAAGGCGCGCTCGATCTACATCGGCGGTTTCGGCGCCAGCGCCTGGCTTGCGGGGTTGCTGCAGCAC
GGGCTCGATGGTTCGTGCAACGACGTGCGCATGCTCTCCAGCGTGAGCGGCGTCACGCACTCGGCGCGCACGCTGATGCA
CGCGGGCCCGCAGGACCTGTTCATCGGCCTGACCTTTCCGCGCTACCTCACCGACACGGTGGCGCTGGCGCAGATCGCGC
GCAGCCAGGGCTGCGCGGTGCTCGCGCTGACCGACCGCCCCAACGCCCCGATCGCGCCGCTGGCCGACGTGGTGCTCTAT
TGCCAGACCGAAACCAGCTACCGCCCCAACTGCGAGACCAGCGTGCTCGCGCTGATCGAGGCACTGACCAGCGCGGTCGC
CCTGCGCGCACCCGGCGCGGCGCAGTCGGCCGGCCGCATCCTGCAGGCGGTGCGTCCGTGGCTGCATGACGGGCTGGGCC
AGGGCCATGCGCGCGGCCAGGTCTCCATGCCTGCCCTCCTTCCCGTTGCCGTCGCTTCCGACGCCGGCAAGAAAAAGAAG
AAAGCTTCCCGATGA

Upstream 100 bases:

>100_bases
TGCGGCACCCTTCGAAAATGACAGAAAATTTTCATATCCATCATATATTTGTAAATATATTTACATCACACGCACCCTTC
CAAGGTGCATCGCCCACCCC

Downstream 100 bases:

>100_bases
AGAACGCCACGCCCGTCATCGCCATCCACGGCGGCGCCGGCACCATCAGCACCTCGACGACCAGCCCCGAGCAGGCGCAG
GCGTATCACGATGCGCTGCA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRTNVDTPGSTVAQRIAQALPRLTRSHRQVADFVLAHPLQVATLPIDELAAAAGVSVATANRFARALDFDGYATFRAELV
RGFESLVAPIERLRGNLEHPTTVAEVFATALDESRRNIEATRQSLDYAACEAAVQRILKARSIYIGGFGASAWLAGLLQH
GLDGSCNDVRMLSSVSGVTHSARTLMHAGPQDLFIGLTFPRYLTDTVALAQIARSQGCAVLALTDRPNAPIAPLADVVLY
CQTETSYRPNCETSVLALIEALTSAVALRAPGAAQSAGRILQAVRPWLHDGLGQGHARGQVSMPALLPVAVASDAGKKKK
KASR

Sequences:

>Translated_324_residues
MRTNVDTPGSTVAQRIAQALPRLTRSHRQVADFVLAHPLQVATLPIDELAAAAGVSVATANRFARALDFDGYATFRAELV
RGFESLVAPIERLRGNLEHPTTVAEVFATALDESRRNIEATRQSLDYAACEAAVQRILKARSIYIGGFGASAWLAGLLQH
GLDGSCNDVRMLSSVSGVTHSARTLMHAGPQDLFIGLTFPRYLTDTVALAQIARSQGCAVLALTDRPNAPIAPLADVVLY
CQTETSYRPNCETSVLALIEALTSAVALRAPGAAQSAGRILQAVRPWLHDGLGQGHARGQVSMPALLPVAVASDAGKKKK
KASR
>Mature_324_residues
MRTNVDTPGSTVAQRIAQALPRLTRSHRQVADFVLAHPLQVATLPIDELAAAAGVSVATANRFARALDFDGYATFRAELV
RGFESLVAPIERLRGNLEHPTTVAEVFATALDESRRNIEATRQSLDYAACEAAVQRILKARSIYIGGFGASAWLAGLLQH
GLDGSCNDVRMLSSVSGVTHSARTLMHAGPQDLFIGLTFPRYLTDTVALAQIARSQGCAVLALTDRPNAPIAPLADVVLY
CQTETSYRPNCETSVLALIEALTSAVALRAPGAAQSAGRILQAVRPWLHDGLGQGHARGQVSMPALLPVAVASDAGKKKK
KASR

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=264, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788767, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 34437; Mature: 34437

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNVDTPGSTVAQRIAQALPRLTRSHRQVADFVLAHPLQVATLPIDELAAAAGVSVATA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHHHHHHCCHHHHH
NRFARALDFDGYATFRAELVRGFESLVAPIERLRGNLEHPTTVAEVFATALDESRRNIEA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TRQSLDYAACEAAVQRILKARSIYIGGFGASAWLAGLLQHGLDGSCNDVRMLSSVSGVTH
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SARTLMHAGPQDLFIGLTFPRYLTDTVALAQIARSQGCAVLALTDRPNAPIAPLADVVLY
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHE
CQTETSYRPNCETSVLALIEALTSAVALRAPGAAQSAGRILQAVRPWLHDGLGQGHARGQ
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
VSMPALLPVAVASDAGKKKKKASR
CCCCHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MRTNVDTPGSTVAQRIAQALPRLTRSHRQVADFVLAHPLQVATLPIDELAAAAGVSVATA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHHHHHHCCHHHHH
NRFARALDFDGYATFRAELVRGFESLVAPIERLRGNLEHPTTVAEVFATALDESRRNIEA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TRQSLDYAACEAAVQRILKARSIYIGGFGASAWLAGLLQHGLDGSCNDVRMLSSVSGVTH
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SARTLMHAGPQDLFIGLTFPRYLTDTVALAQIARSQGCAVLALTDRPNAPIAPLADVVLY
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHE
CQTETSYRPNCETSVLALIEALTSAVALRAPGAAQSAGRILQAVRPWLHDGLGQGHARGQ
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
VSMPALLPVAVASDAGKKKKKASR
CCCCHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]