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The map label for this gene is ftsW [H]

Identifier: 121611478

GI number: 121611478

Start: 5059225

End: 5060481

Strand: Direct

Name: ftsW [H]

Synonym: Veis_4569

Alternate gene names: 121611478

Gene position: 5059225-5060481 (Clockwise)

Preceding gene: 121611477

Following gene: 121611479

Centisome position: 90.88

GC content: 67.94

Gene sequence:

>1257_bases
ATGCCGCGACTGCTGCAATGGATCACCGGCTGGTTCGACGGCCAGTCGGGCCAGGCTGCCGACCGGCTGCCGGTGCGCGT
GGGCGGCACCGAGTACCGCCGCGCGTCGAGCACCCCGGTCAGCCCGCCCGGGTTCGATCAGCCCCTGCTGTGGGTGATGG
TGGCGCTGCTGGCCTGGGGGCTGGTGATGGTGTATTCGGCATCGATCGCGATGCCGGACAACCCGCGCTTTGCCCACTAT
GCGTCCACCCATTTCCTGAGCCGCCATGCGCTGTCCCTGGTGATCGGCGCGCTGGTGGCGCTGCTGAGCTTCCAGTTGCC
GATGGCGCAGTGGGAGCGGATGGCGCCCTGGCTGTTCGTCGCCACGCTGGCGCTGCTGACGCTGGTGCTGCTGCCCGGGG
CCGGCAAGGTGGTCAAGGGCGCGCGCCGCTGGCTGACGCTCGGGCCGGTGAGTTTTCAGCCCTCCGAACTGGCCAAGCTG
GCCATGCTGCTCTACGCCGCCGGCTACATGGTGCGCAAGATGGAGGTCAAGGAGCGCTTCTTTCGCGCCGTGCTGCCGAT
GGCCTGCGCCGTGGCCATCGTCGGCGTGTTGCTGCTGGCCGAGCCGGACATGGGCGCCTTCATCGTGGTCGCGATGATCG
CCATGGGCATCCTGTTTCTCGGCGGCGTCAACGCCCGCATGTTCCTGCTGATCGTCGCCGTGCTGCTGGCGGCCTTTCTG
CTGATGATTGCCAACTCGCCCTGGCGGCGCGAGCGCGTGTTCGCCTACCTCGACCCGTTTGGCGCGGAACATGCGCAGGG
CAAGGGCTACCAGCTCTCGCACGCGCTGATCGCGATCGGGCGCGGGGAGATTTTTGGCGTCGGTCTGGGCGGCAGCGTGG
AGAAACTGCACTGGCTGCCCGAGGCCCATACCGACTTTCTGCTGGCCGTCATCGGCGAGGAGTTCGGCCTGCTGGGCGTG
CTCGCATTGATCGTGCTGTTCCTGTGGATGACGCGCCGCATCATGCACATCGGGCGCCAGGCCATCGCGCTGGAGCGCGT
GTTCTCCGGCCTGGTCGCGCAGGGGGTGGGCATCTGGCTCGGCCTGCAGGCATTCATCAACATGGGGGTGAACCTGGGCG
CGCTGCCGACCAAGGGGCTGACGCTGCCGCTGATGAGCTTTGGCGGCTCGGCAATCCTGATGAACCTGGTGGCGTTGGCG
CTCGTGCTGCGGGTCGATCATGAGAACAAGCGCCTGATGCGCGGGGGCCGCGCATGA

Upstream 100 bases:

>100_bases
ACATGTTCCGGGACTACGAACAGCGCGCGCAGGTTTTTTGCGCCAGCGTGCGCGCATTGGCCGAGGCAGCCGGCCAGCCG
ATGGAGGGTCTGGCATGAAC

Downstream 100 bases:

>100_bases
CGGGCAGCAAAACCGCGCTGATCATGGCCGGCGGCACGGGCGGGCATATCTTTCCCGGCCTGGCCGTGGCCGAGGCGCTG
CGCGCGCGCGGCTGGCGCGT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MPRLLQWITGWFDGQSGQAADRLPVRVGGTEYRRASSTPVSPPGFDQPLLWVMVALLAWGLVMVYSASIAMPDNPRFAHY
ASTHFLSRHALSLVIGALVALLSFQLPMAQWERMAPWLFVATLALLTLVLLPGAGKVVKGARRWLTLGPVSFQPSELAKL
AMLLYAAGYMVRKMEVKERFFRAVLPMACAVAIVGVLLLAEPDMGAFIVVAMIAMGILFLGGVNARMFLLIVAVLLAAFL
LMIANSPWRRERVFAYLDPFGAEHAQGKGYQLSHALIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVIGEEFGLLGV
LALIVLFLWMTRRIMHIGRQAIALERVFSGLVAQGVGIWLGLQAFINMGVNLGALPTKGLTLPLMSFGGSAILMNLVALA
LVLRVDHENKRLMRGGRA

Sequences:

>Translated_418_residues
MPRLLQWITGWFDGQSGQAADRLPVRVGGTEYRRASSTPVSPPGFDQPLLWVMVALLAWGLVMVYSASIAMPDNPRFAHY
ASTHFLSRHALSLVIGALVALLSFQLPMAQWERMAPWLFVATLALLTLVLLPGAGKVVKGARRWLTLGPVSFQPSELAKL
AMLLYAAGYMVRKMEVKERFFRAVLPMACAVAIVGVLLLAEPDMGAFIVVAMIAMGILFLGGVNARMFLLIVAVLLAAFL
LMIANSPWRRERVFAYLDPFGAEHAQGKGYQLSHALIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVIGEEFGLLGV
LALIVLFLWMTRRIMHIGRQAIALERVFSGLVAQGVGIWLGLQAFINMGVNLGALPTKGLTLPLMSFGGSAILMNLVALA
LVLRVDHENKRLMRGGRA
>Mature_417_residues
PRLLQWITGWFDGQSGQAADRLPVRVGGTEYRRASSTPVSPPGFDQPLLWVMVALLAWGLVMVYSASIAMPDNPRFAHYA
STHFLSRHALSLVIGALVALLSFQLPMAQWERMAPWLFVATLALLTLVLLPGAGKVVKGARRWLTLGPVSFQPSELAKLA
MLLYAAGYMVRKMEVKERFFRAVLPMACAVAIVGVLLLAEPDMGAFIVVAMIAMGILFLGGVNARMFLLIVAVLLAAFLL
MIANSPWRRERVFAYLDPFGAEHAQGKGYQLSHALIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVIGEEFGLLGVL
ALIVLFLWMTRRIMHIGRQAIALERVFSGLVAQGVGIWLGLQAFINMGVNLGALPTKGLTLPLMSFGGSAILMNLVALAL
VLRVDHENKRLMRGGRA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=419, Percent_Identity=38.4248210023866, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=33.6309523809524, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45500; Mature: 45369

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLQWITGWFDGQSGQAADRLPVRVGGTEYRRASSTPVSPPGFDQPLLWVMVALLAWG
CCHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LVMVYSASIAMPDNPRFAHYASTHFLSRHALSLVIGALVALLSFQLPMAQWERMAPWLFV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHH
ATLALLTLVLLPGAGKVVKGARRWLTLGPVSFQPSELAKLAMLLYAAGYMVRKMEVKERF
HHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRAVLPMACAVAIVGVLLLAEPDMGAFIVVAMIAMGILFLGGVNARMFLLIVAVLLAAFL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LMIANSPWRRERVFAYLDPFGAEHAQGKGYQLSHALIAIGRGEIFGVGLGGSVEKLHWLP
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHHHHEEECCCCEEEECCCCCHHHHHCCC
EAHTDFLLAVIGEEFGLLGVLALIVLFLWMTRRIMHIGRQAIALERVFSGLVAQGVGIWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQAFINMGVNLGALPTKGLTLPLMSFGGSAILMNLVALALVLRVDHENKRLMRGGRA
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
PRLLQWITGWFDGQSGQAADRLPVRVGGTEYRRASSTPVSPPGFDQPLLWVMVALLAWG
CHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LVMVYSASIAMPDNPRFAHYASTHFLSRHALSLVIGALVALLSFQLPMAQWERMAPWLFV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHH
ATLALLTLVLLPGAGKVVKGARRWLTLGPVSFQPSELAKLAMLLYAAGYMVRKMEVKERF
HHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRAVLPMACAVAIVGVLLLAEPDMGAFIVVAMIAMGILFLGGVNARMFLLIVAVLLAAFL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LMIANSPWRRERVFAYLDPFGAEHAQGKGYQLSHALIAIGRGEIFGVGLGGSVEKLHWLP
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHHHHEEECCCCEEEECCCCCHHHHHCCC
EAHTDFLLAVIGEEFGLLGVLALIVLFLWMTRRIMHIGRQAIALERVFSGLVAQGVGIWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQAFINMGVNLGALPTKGLTLPLMSFGGSAILMNLVALALVLRVDHENKRLMRGGRA
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]