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The map label for this gene is murG

Identifier: 121611479

GI number: 121611479

Start: 5060478

End: 5061557

Strand: Direct

Name: murG

Synonym: Veis_4570

Alternate gene names: 121611479

Gene position: 5060478-5061557 (Clockwise)

Preceding gene: 121611478

Following gene: 121611480

Centisome position: 90.91

GC content: 73.52

Gene sequence:

>1080_bases
ATGACGGGCAGCAAAACCGCGCTGATCATGGCCGGCGGCACGGGCGGGCATATCTTTCCCGGCCTGGCCGTGGCCGAGGC
GCTGCGCGCGCGCGGCTGGCGCGTGCATTGGCTGGGGGCGCCGGCCAGCATGGAGGCGCGCATCGCTGCGCAGCATGGCT
TTGCGCTGGAATCGGTGACTTTCTCCGGCGTGCGCGGCAAGGGCCTGGCCACGCTGGCGCTGCTGCCGCTGCGCCTGCTG
CGCGCGTTCTGGCAGGCGCGCGCGGTGCTGCGCCGCGTGCAGCCCGATGTGCTGGTGGGACTGGGCGGCTACATCAGCTT
TCCGGGCGCGCTGATGGGCCTGCTGCGCCGCAAACCGCTGGTGCTGCATGAGCAAAACGCGGTCGCGGGGCTGGCCAACC
GGCTGCTGGCGGGGCGGGCCGACCGGGTGTTCGCCGCCTTTCCCGGCGCGTTCGGCAGCGCAGCGCCCAAAGCCCGCTGG
GTCGGCAACCCGCTGCGCGCGGCGTTCACGCAGCAGGCCGGCCCGGCCGAGCGCTTTGCGGCGCGCACCGGGCCGCTGCA
ACTGCTGGTCATGGGCGGCAGCCTGGGCGCGCGCGCGCTCAACGAACTCGTGCCGCAGGCGCTGGCGCTGCTGCCGGCCG
CGCAGCGCCCGCAGGTGCTGCACCAAAGCGGCGCCACGCAGATCGAGGCCCTGCGCGCCCATTACGCCGCCGCCGGGGTG
CAGGCCGAGCTCAGGCCGTTCATCGACGACGTGGCCTGCGCGCTGGCCGCCGCCGATGTCATCGTCTGCCGCGCGGGCGC
CAGCACCGTCAGCGAAATCGCTGCCGTGGGCGCTGCGGCGCTGTTCGTGCCGCTGCCCTCGGCGGTCGACGACCACCAGA
CCCGCAACGCCCGCTGGCTGGTCGACGCGGGGGGCGGCTGGCTGCTGCCGCAGCACGAGCTATCGCCCCGGGGCCTGGCG
CAGATGCTATCGAACCTGGAGCGCCCTGCGCTGCTGGACAAAGCGCTCAAAGCCCACGCGATGCAAAAGACAAGCGCCAC
GCAAGAGTTGGTCGGCGCCTGCGAGGAGTTGGCCGCATGA

Upstream 100 bases:

>100_bases
TGAGCTTTGGCGGCTCGGCAATCCTGATGAACCTGGTGGCGTTGGCGCTCGTGCTGCGGGTCGATCATGAGAACAAGCGC
CTGATGCGCGGGGGCCGCGC

Downstream 100 bases:

>100_bases
AGCATGCCATCCGCCATATCCATTTCGTCGGCCTGGGCGGCGCCGGCATGAGCGGCATCGCCGAGGTGCTGTTCAACCTG
GGCTACCGCATCTCGGGCTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVTFSGVRGKGLATLALLPLRLL
RAFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPLVLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARW
VGNPLRAAFTQQAGPAERFAARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGV
QAELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWLVDAGGGWLLPQHELSPRGLA
QMLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA

Sequences:

>Translated_359_residues
MTGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVTFSGVRGKGLATLALLPLRLL
RAFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPLVLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARW
VGNPLRAAFTQQAGPAERFAARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGV
QAELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWLVDAGGGWLLPQHELSPRGLA
QMLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA
>Mature_358_residues
TGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVTFSGVRGKGLATLALLPLRLLR
AFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPLVLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARWV
GNPLRAAFTQQAGPAERFAARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGVQ
AELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWLVDAGGGWLLPQHELSPRGLAQ
MLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=45.2777777777778, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_VEREI (A1WRL1)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_999286.1
- ProteinModelPortal:   A1WRL1
- SMR:   A1WRL1
- STRING:   A1WRL1
- GeneID:   4694346
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_4570
- NMPDR:   fig|391735.5.peg.4190
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A1WRL1
- ProtClustDB:   PRK00726
- BioCyc:   VEIS391735:VEIS_4570-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37496; Mature: 37365

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVT
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCEEHHEE
FSGVRGKGLATLALLPLRLLRAFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCHHHHHHHHHCCCC
VLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARWVGNPLRAAFTQQAGPAERFA
EEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHCCCHHHHHHHHCCCCHHHHH
ARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGV
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC
QAELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWL
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEE
VDAGGGWLLPQHELSPRGLAQMLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA
EECCCCEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGSKTALIMAGGTGGHIFPGLAVAEALRARGWRVHWLGAPASMEARIAAQHGFALESVT
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCEEHHEE
FSGVRGKGLATLALLPLRLLRAFWQARAVLRRVQPDVLVGLGGYISFPGALMGLLRRKPL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCHHHHHHHHHCCCC
VLHEQNAVAGLANRLLAGRADRVFAAFPGAFGSAAPKARWVGNPLRAAFTQQAGPAERFA
EEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHCCCHHHHHHHHCCCCHHHHH
ARTGPLQLLVMGGSLGARALNELVPQALALLPAAQRPQVLHQSGATQIEALRAHYAAAGV
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC
QAELRPFIDDVACALAAADVIVCRAGASTVSEIAAVGAAALFVPLPSAVDDHQTRNARWL
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEE
VDAGGGWLLPQHELSPRGLAQMLSNLERPALLDKALKAHAMQKTSATQELVGACEELAA
EECCCCEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA