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The map label for this gene is dppB [H]

Identifier: 121611405

GI number: 121611405

Start: 4972536

End: 4973552

Strand: Direct

Name: dppB [H]

Synonym: Veis_4494

Alternate gene names: 121611405

Gene position: 4972536-4973552 (Clockwise)

Preceding gene: 121611404

Following gene: 121611406

Centisome position: 89.33

GC content: 66.76

Gene sequence:

>1017_bases
ATGTTCCCGCTCATTTCCGCGATCGTCCTGCGCCGGCTGCTGCTGGCCATCCCGACCCTGCTGCTGTTGTCGCTGGTGGT
GTTCGTCGTGCTGCGCATGCTGCCGGTGGATCCGCTGGTGCTGCTGCTGCCGGCATCGGCCACGGCAGCGGATGCCGCAG
TGCTGCGGGAGCAGCTCGGTTTCGACAAGCCCGTGCCGCAGCAATTCCTCATCTGGCTGTGGCAGGCATTCAACGGCAAC
CTGGGCACCTCGATCAACTTCCGCCAGCCGGTCGCCCACCTGATGCTGTCCTCGCTGCCGGCGACGCTGGAGCTGACGCT
GGCCGGCCTGCTGCTTGCGCTTGTGATCAGCGTGCCAGGCGGCGTGCTGGCCTACGCGCTCTACCAGCGCCGGCGCGAAA
CCGCCGCAGACCTCGCGGTGGCATCGATGCAGTCAATCCCTTCCTTCCTCTGGAGTCTGTTGCTGATCCTGACCTTCGGC
GTGCTGTGGCCCGTGCTGCCCTTCAGCGGGCGGGTCGGCGTAGGCGTTGCGCTGCCCGACATCACCGGCTTCGCCGTCAT
CGACCTTCTGCTGGTGGGGCGCTTCGATGCCTGGCTCACGGCGCTGTCGCACCTGCTGCTGCCGGCGCTGGCCCTGGCCC
TGGGCTTCGCGCCGCTCGTGATCCGGGTGCTGCGCTCCAGCCTGATCGACGCCGCGAGCGAGCCCTACGTGGAAGCGGCG
CGGCTGCGCGGGCTGTCGGAAACGCGCATCGTGTGGCGCCACATGCTGAAAAACGCGGCGCTGCCCACGGTCACCATGAT
CGGCGTGCAGTTCGGCTTCCTGTTCGGCGGCGCGTTGCTGGTGGAAATGATCTTCGGCTTCCCCGGCGTCGGGAACCTGA
TGGTGCAGGCGGTCAGGGGCAACGACCTGCCATTGATCCAGGGCATTGCCCTGATCTTCTGCGTGCTGATGCTGGCGATC
ACGGTGATCGTCGACGTTCTGTATGCCGTGTTGAACCCGCGACTGAGAACGCCATGA

Upstream 100 bases:

>100_bases
GCAGCCCACCCTGTTCGACAACGGCTACATCCTGCCGGCTGACATGAAGTACCGCTGAACCGGCCTCGCCCACTGACAGG
CCGCGCGCAGGATCCACCAC

Downstream 100 bases:

>100_bases
CCGCGACGGCAATGCCCACCTCGCCGGCCCCGACGGCCCCGACGACCCTCTGCGCTGGCGTCACCTGCGGCGCGTTGCGC
CAGTTGGGTCGCCAGCCGCG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MFPLISAIVLRRLLLAIPTLLLLSLVVFVVLRMLPVDPLVLLLPASATAADAAVLREQLGFDKPVPQQFLIWLWQAFNGN
LGTSINFRQPVAHLMLSSLPATLELTLAGLLLALVISVPGGVLAYALYQRRRETAADLAVASMQSIPSFLWSLLLILTFG
VLWPVLPFSGRVGVGVALPDITGFAVIDLLLVGRFDAWLTALSHLLLPALALALGFAPLVIRVLRSSLIDAASEPYVEAA
RLRGLSETRIVWRHMLKNAALPTVTMIGVQFGFLFGGALLVEMIFGFPGVGNLMVQAVRGNDLPLIQGIALIFCVLMLAI
TVIVDVLYAVLNPRLRTP

Sequences:

>Translated_338_residues
MFPLISAIVLRRLLLAIPTLLLLSLVVFVVLRMLPVDPLVLLLPASATAADAAVLREQLGFDKPVPQQFLIWLWQAFNGN
LGTSINFRQPVAHLMLSSLPATLELTLAGLLLALVISVPGGVLAYALYQRRRETAADLAVASMQSIPSFLWSLLLILTFG
VLWPVLPFSGRVGVGVALPDITGFAVIDLLLVGRFDAWLTALSHLLLPALALALGFAPLVIRVLRSSLIDAASEPYVEAA
RLRGLSETRIVWRHMLKNAALPTVTMIGVQFGFLFGGALLVEMIFGFPGVGNLMVQAVRGNDLPLIQGIALIFCVLMLAI
TVIVDVLYAVLNPRLRTP
>Mature_338_residues
MFPLISAIVLRRLLLAIPTLLLLSLVVFVVLRMLPVDPLVLLLPASATAADAAVLREQLGFDKPVPQQFLIWLWQAFNGN
LGTSINFRQPVAHLMLSSLPATLELTLAGLLLALVISVPGGVLAYALYQRRRETAADLAVASMQSIPSFLWSLLLILTFG
VLWPVLPFSGRVGVGVALPDITGFAVIDLLLVGRFDAWLTALSHLLLPALALALGFAPLVIRVLRSSLIDAASEPYVEAA
RLRGLSETRIVWRHMLKNAALPTVTMIGVQFGFLFGGALLVEMIFGFPGVGNLMVQAVRGNDLPLIQGIALIFCVLMLAI
TVIVDVLYAVLNPRLRTP

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=36.9047619047619, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787053, Length=329, Percent_Identity=36.7781155015198, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=36.4179104477612, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787761, Length=314, Percent_Identity=34.7133757961783, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787497, Length=333, Percent_Identity=30.6306306306306, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=33.4558823529412, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788504, Length=379, Percent_Identity=25.8575197889182, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36517; Mature: 36517

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPLISAIVLRRLLLAIPTLLLLSLVVFVVLRMLPVDPLVLLLPASATAADAAVLREQLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHC
FDKPVPQQFLIWLWQAFNGNLGTSINFRQPVAHLMLSSLPATLELTLAGLLLALVISVPG
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
GVLAYALYQRRRETAADLAVASMQSIPSFLWSLLLILTFGVLWPVLPFSGRVGVGVALPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCC
ITGFAVIDLLLVGRFDAWLTALSHLLLPALALALGFAPLVIRVLRSSLIDAASEPYVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLRGLSETRIVWRHMLKNAALPTVTMIGVQFGFLFGGALLVEMIFGFPGVGNLMVQAVRG
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NDLPLIQGIALIFCVLMLAITVIVDVLYAVLNPRLRTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFPLISAIVLRRLLLAIPTLLLLSLVVFVVLRMLPVDPLVLLLPASATAADAAVLREQLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHC
FDKPVPQQFLIWLWQAFNGNLGTSINFRQPVAHLMLSSLPATLELTLAGLLLALVISVPG
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
GVLAYALYQRRRETAADLAVASMQSIPSFLWSLLLILTFGVLWPVLPFSGRVGVGVALPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCC
ITGFAVIDLLLVGRFDAWLTALSHLLLPALALALGFAPLVIRVLRSSLIDAASEPYVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLRGLSETRIVWRHMLKNAALPTVTMIGVQFGFLFGGALLVEMIFGFPGVGNLMVQAVRG
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NDLPLIQGIALIFCVLMLAITVIVDVLYAVLNPRLRTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]