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The map label for this gene is tig

Identifier: 121611284

GI number: 121611284

Start: 4818595

End: 4819917

Strand: Direct

Name: tig

Synonym: Veis_4370

Alternate gene names: 121611284

Gene position: 4818595-4819917 (Clockwise)

Preceding gene: 121611282

Following gene: 121611285

Centisome position: 86.56

GC content: 63.11

Gene sequence:

>1323_bases
ATGGCCGTTACTGTTGAAACCCTTGACAAGCTCGAGCGCAAGATGACGCTGAGCCTGCCCGTCACCCTGATCCAGTCCGA
AGTCGACATGCGCCTGCGGCGCATGGCACGCACGGTCAAGATGGATGGCTTTCGTCCGGGCAAGGTGCCGATGGCCGTGG
TCGCCCGGCGCTATGGCGACGCGGTGCAGTACGAAGTGCTCACCAACAAGGTCGGCGAAGCCTTTACCGTGGCGGCCAAC
GAGGCCAATCTGCGCGTCGCCGGCCGGCCGCGCATCACCGAGACGCAAGGCACTGCCGAAGGCCATGTCACGTTTGACGC
CATCTTCGAGGTGTTCCCTGAAGTCAGGATTGCCGATCTGGCCAATGTCGAAATCGAAAAGCTGTCTACCGAAGTGACCG
AAGCCTCCATCGACAAGACGCTGCAGGGGCTGCGCAAGCAGCGCCGCAGCTTTGCGCAGCGCGCCCATGATGCGCCGGCG
CAAGATGGCGACGGCGTGACGGTCGACTTCGAGGGCAAGATCGATGGCGAGCCGTTTGCCAATGGCAAGGCGGAGAACTT
CCGTTTCGTGATCGGCGAAGGCCCGATGCCCAAGGAATTCGAGGACGCCGTGCGCGGCATGAAGTCGGGCGAGAGCAAGA
CCTTTCCGCTGGCATTCCCGACCCAATACCATGGCCAGGAGGTGGCCGGCAAGACGGCGGACTTCCTGGTGACGGTCAAG
AAGATCGAATCCGCCCACCTGCCCGAAGTGGGCGAGGCCCTGGCCAGGTCGCTCGGTAGCGCCGACGGTTCCATCGAGGG
CCTGCGCGCTGACATCAGGAAGACCCTGGAGCGCGAAATCAGATCCCACCTGCGCGCGCGCAACAGGCGGGCCGTAATGA
ACGCCCTGCTCGCCAACGCCGATCTGGAACTGCCCAAGGCCAGCGTGCAGGACGAAATCGCCCGCCTGAAGGCCAACGCC
TACGCCGACCTCAAGCAAAGAGGCGTCAAGGACCCCGAAAGGCTCGAGATTCCCGAAGACAAGGTGCGGCCCACGGCCGA
GCGCAATGTGCGCCTGCGACTGATCTTTTCGGAAATGGTGCGCGCCCATGGACTGCGGGCCAAGCCCGAGCAGGTCAGGG
CCTATGTCGAGGAATTGGCGGCCAGCTACGAAAAGCCCGCCGAGATGGTGCGCGGGTACTACGGCGACCGTCGGCGGATG
CTCGAAATCGAATCCTCCGTGAGCGAGGACAACGTGACCGAATTCGTTTTCGCCCGGGCCAAAGTGGTCGCAAGGACCAT
CTCGGTCGACGAGTTGCTCAATCCAAAGGATCCAAAGGACTGA

Upstream 100 bases:

>100_bases
ATGGTGTGGGGGTTCGAGTCCCCCCCCGCGCACCATCCATGCGAGACTTTGCGCAGCCGGCACGGTCCACATTCATACAG
AGTCATACAGAGGAAGAGCC

Downstream 100 bases:

>100_bases
CGCCACGGACCGGTTTCTGACTACAGGCATCTGCCCGACGGGAGAAAAGACATGAATGCATTGGAAACACAGGGCCTGGG
GATGATCCCCATGGTCATCG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGDAVQYEVLTNKVGEAFTVAAN
EANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADLANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPA
QDGDGVTVDFEGKIDGEPFANGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVK
KIESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANADLELPKASVQDEIARLKANA
YADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMVRAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRM
LEIESSVSEDNVTEFVFARAKVVARTISVDELLNPKDPKD

Sequences:

>Translated_440_residues
MAVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGDAVQYEVLTNKVGEAFTVAAN
EANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADLANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPA
QDGDGVTVDFEGKIDGEPFANGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVK
KIESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANADLELPKASVQDEIARLKANA
YADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMVRAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRM
LEIESSVSEDNVTEFVFARAKVVARTISVDELLNPKDPKD
>Mature_439_residues
AVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGDAVQYEVLTNKVGEAFTVAANE
ANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADLANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPAQ
DGDGVTVDFEGKIDGEPFANGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVKK
IESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANADLELPKASVQDEIARLKANAY
ADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMVRAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRML
EIESSVSEDNVTEFVFARAKVVARTISVDELLNPKDPKD

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=436, Percent_Identity=35.3211009174312, Blast_Score=281, Evalue=5e-77,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_VEREI (A1WR16)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_999091.1
- ProteinModelPortal:   A1WR16
- SMR:   A1WR16
- STRING:   A1WR16
- GeneID:   4691141
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_4370
- NMPDR:   fig|391735.5.peg.4001
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- PhylomeDB:   A1WR16
- ProtClustDB:   PRK01490
- BioCyc:   VEIS391735:VEIS_4370-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49076; Mature: 48944

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGD
CEEEHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
AVQYEVLTNKVGEAFTVAANEANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADL
HHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
ANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPAQDGDGVTVDFEGKIDGEPFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC
NGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVK
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHCCCHHHHHHHHH
KIESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANA
HHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DLELPKASVQDEIARLKANAYADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHCCCCHHCCCEEEHHHHHHH
RAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRMLEIESSVSEDNVTEFVFARA
HHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHH
KVVARTISVDELLNPKDPKD
HHHHHHHCHHHHCCCCCCCC
>Mature Secondary Structure 
AVTVETLDKLERKMTLSLPVTLIQSEVDMRLRRMARTVKMDGFRPGKVPMAVVARRYGD
EEEHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
AVQYEVLTNKVGEAFTVAANEANLRVAGRPRITETQGTAEGHVTFDAIFEVFPEVRIADL
HHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
ANVEIEKLSTEVTEASIDKTLQGLRKQRRSFAQRAHDAPAQDGDGVTVDFEGKIDGEPFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC
NGKAENFRFVIGEGPMPKEFEDAVRGMKSGESKTFPLAFPTQYHGQEVAGKTADFLVTVK
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHCCCHHHHHHHHH
KIESAHLPEVGEALARSLGSADGSIEGLRADIRKTLEREIRSHLRARNRRAVMNALLANA
HHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DLELPKASVQDEIARLKANAYADLKQRGVKDPERLEIPEDKVRPTAERNVRLRLIFSEMV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHCCCCHHCCCEEEHHHHHHH
RAHGLRAKPEQVRAYVEELAASYEKPAEMVRGYYGDRRRMLEIESSVSEDNVTEFVFARA
HHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHH
KVVARTISVDELLNPKDPKD
HHHHHHHCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA