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The map label for this gene is intA [H]

Identifier: 121610579

GI number: 121610579

Start: 4039191

End: 4040354

Strand: Direct

Name: intA [H]

Synonym: Veis_3652

Alternate gene names: 121610579

Gene position: 4039191-4040354 (Clockwise)

Preceding gene: 121610578

Following gene: 121610580

Centisome position: 72.56

GC content: 63.75

Gene sequence:

>1164_bases
ATGACATTGACCGTGCGTGCAGTGGAGGCGGCAAAGCCGCGTCACAAGGGCTACAAGTTGGCCGACAGTGTGGGGTTGTA
CCTTTTCGTCACCCCGGCCGGTGGCAAGAGTTGGCGCGCCAACTATCTGCGCGAGGGCAAGCAGGCAACGCGCACCTATG
GCCGATGGCCGGATGTCAGCCTGGCCGAGGCCCGCAAAGCCCACGCCGCAGCGCGCGATGGTGTGGTTCCGGCGACGGTC
GCTGTGCCTTCTTTTGAGACGATCGCCAGGGCCTGGCTCAAACTCAAGCTGCCTACCCTGTCCAATGGCAAGCACCAATC
CCAGGTGGCGAACACGCTGGAGCGTTTCGTTTTCCCCAAAATCGGCAAGCGCCCCATCGATACCATCCATCGCCCCGAAC
TGGTGGATGTGGTGCAGGCTGTGCAGCTCGATGGGCGCGTGGAGACGGCCCACCGGGTGGCCGGGCGCATCGCGGCGGTG
TTTGACTATGCCCAGGATGCCGGCCTGATCGAGAGCCATCCGGCATCCCATCTCGTGCGCGTGCTGCACTCACGCAAAGT
AAAGAAACCCATGGCCAGCATTGCCCCTGCCGAGGCCGGGGCGTTGATGCGCGCCATCACCGACTACGATGAGCCTGTGA
CCGGGCTGGGATTGCAACTGCTGGCGCACACGTTCGTGCGGGTCGGGGAACTGCGCGCGATGCGTTGGAGCGAGTTCAAG
GAGGACGGTGCGGTGTGGGTCATTCCCGCCGAGCGCATGAAGCTGCGCTTGCCGCATGTCGTGCCTTTGTCGCTGCAGGC
GCAGGCCATCGTCGGGCAGTTGCGCCTGCTCAACGCTGAGCGGGAGTTCGTCATGGATTCGCCGTTGCGTCCCGGCCACC
CATTGTCTGAAAACACTTTCCTGTTTGCCTTGTATCGCCTGGGCTACCGTGGCCGCATGACGGCCCATGGCTTTCGGGCG
CTGGCCTCTACCGTGCTCAATGAGCAGTCGGGCTTTGCGCACGATGTGATCGAGCGCCAGCTCGCGCACAAGGAAACCGA
TGCGGTGCGCGCTGCGTACAACCGTGCGCAGTATCTGCCGCAGCGGCGCGAGCTCATGCAGTGGTGGGCTCAGTGGCTTG
CTGCTGCACAAACTTCTTCAGATCCTCGACACGCCAGCGCGTGA

Upstream 100 bases:

>100_bases
TGGAGATGTCGTCCATAATCGCCCAAAACACACCATGCCGATACCGCGCAAGCCAAGTGTCAATCATGGTATCTGGCGTG
GTATTTGACGGGGCGATACC

Downstream 100 bases:

>100_bases
GTCCGCCGATTTTGATCGGTTCGGGCAATGTCCCCCGGGCCACTTCGCGCCAGAAGGTGGATTTGCCCATGCTCAGCAGC
GCTGCGGCCTCTGCGGCCGG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTLTVRAVEAAKPRHKGYKLADSVGLYLFVTPAGGKSWRANYLREGKQATRTYGRWPDVSLAEARKAHAAARDGVVPATV
AVPSFETIARAWLKLKLPTLSNGKHQSQVANTLERFVFPKIGKRPIDTIHRPELVDVVQAVQLDGRVETAHRVAGRIAAV
FDYAQDAGLIESHPASHLVRVLHSRKVKKPMASIAPAEAGALMRAITDYDEPVTGLGLQLLAHTFVRVGELRAMRWSEFK
EDGAVWVIPAERMKLRLPHVVPLSLQAQAIVGQLRLLNAEREFVMDSPLRPGHPLSENTFLFALYRLGYRGRMTAHGFRA
LASTVLNEQSGFAHDVIERQLAHKETDAVRAAYNRAQYLPQRRELMQWWAQWLAAAQTSSDPRHASA

Sequences:

>Translated_387_residues
MTLTVRAVEAAKPRHKGYKLADSVGLYLFVTPAGGKSWRANYLREGKQATRTYGRWPDVSLAEARKAHAAARDGVVPATV
AVPSFETIARAWLKLKLPTLSNGKHQSQVANTLERFVFPKIGKRPIDTIHRPELVDVVQAVQLDGRVETAHRVAGRIAAV
FDYAQDAGLIESHPASHLVRVLHSRKVKKPMASIAPAEAGALMRAITDYDEPVTGLGLQLLAHTFVRVGELRAMRWSEFK
EDGAVWVIPAERMKLRLPHVVPLSLQAQAIVGQLRLLNAEREFVMDSPLRPGHPLSENTFLFALYRLGYRGRMTAHGFRA
LASTVLNEQSGFAHDVIERQLAHKETDAVRAAYNRAQYLPQRRELMQWWAQWLAAAQTSSDPRHASA
>Mature_386_residues
TLTVRAVEAAKPRHKGYKLADSVGLYLFVTPAGGKSWRANYLREGKQATRTYGRWPDVSLAEARKAHAAARDGVVPATVA
VPSFETIARAWLKLKLPTLSNGKHQSQVANTLERFVFPKIGKRPIDTIHRPELVDVVQAVQLDGRVETAHRVAGRIAAVF
DYAQDAGLIESHPASHLVRVLHSRKVKKPMASIAPAEAGALMRAITDYDEPVTGLGLQLLAHTFVRVGELRAMRWSEFKE
DGAVWVIPAERMKLRLPHVVPLSLQAQAIVGQLRLLNAEREFVMDSPLRPGHPLSENTFLFALYRLGYRGRMTAHGFRAL
ASTVLNEQSGFAHDVIERQLAHKETDAVRAAYNRAQYLPQRRELMQWWAQWLAAAQTSSDPRHASA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=400, Percent_Identity=37, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788690, Length=382, Percent_Identity=34.5549738219895, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI145693166, Length=392, Percent_Identity=34.1836734693878, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43108; Mature: 42977

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTVRAVEAAKPRHKGYKLADSVGLYLFVTPAGGKSWRANYLREGKQATRTYGRWPDVS
CEEEEEEHHHCCCHHCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCH
LAEARKAHAAARDGVVPATVAVPSFETIARAWLKLKLPTLSNGKHQSQVANTLERFVFPK
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCC
IGKRPIDTIHRPELVDVVQAVQLDGRVETAHRVAGRIAAVFDYAQDAGLIESHPASHLVR
CCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
VLHSRKVKKPMASIAPAEAGALMRAITDYDEPVTGLGLQLLAHTFVRVGELRAMRWSEFK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGAVWVIPAERMKLRLPHVVPLSLQAQAIVGQLRLLNAEREFVMDSPLRPGHPLSENTF
CCCCEEEEEHHHHHEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHH
LFALYRLGYRGRMTAHGFRALASTVLNEQSGFAHDVIERQLAHKETDAVRAAYNRAQYLP
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QRRELMQWWAQWLAAAQTSSDPRHASA
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TLTVRAVEAAKPRHKGYKLADSVGLYLFVTPAGGKSWRANYLREGKQATRTYGRWPDVS
EEEEEEHHHCCCHHCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCH
LAEARKAHAAARDGVVPATVAVPSFETIARAWLKLKLPTLSNGKHQSQVANTLERFVFPK
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCC
IGKRPIDTIHRPELVDVVQAVQLDGRVETAHRVAGRIAAVFDYAQDAGLIESHPASHLVR
CCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
VLHSRKVKKPMASIAPAEAGALMRAITDYDEPVTGLGLQLLAHTFVRVGELRAMRWSEFK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGAVWVIPAERMKLRLPHVVPLSLQAQAIVGQLRLLNAEREFVMDSPLRPGHPLSENTF
CCCCEEEEEHHHHHEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHH
LFALYRLGYRGRMTAHGFRALASTVLNEQSGFAHDVIERQLAHKETDAVRAAYNRAQYLP
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QRRELMQWWAQWLAAAQTSSDPRHASA
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]