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The map label for this gene is dgoD [H]

Identifier: 121609856

GI number: 121609856

Start: 3256885

End: 3258132

Strand: Direct

Name: dgoD [H]

Synonym: Veis_2909

Alternate gene names: 121609856

Gene position: 3256885-3258132 (Clockwise)

Preceding gene: 121609855

Following gene: 121609857

Centisome position: 58.51

GC content: 60.02

Gene sequence:

>1248_bases
ATGAAAATCATATCGATGAAATCCCATGTGGTTGCCGTGCCGCCGCCCTATATCGGCGGCATGTACTGGATTTTCGTCAC
CCTGAAAACCGCTTGCGGCATCGAGGGCGTGGGCGAAATCTACGCCTCCACATTTCACCCCAAGGTGGTCGCCTGCGCCA
TGGATGACGTGTTCGAGCGGCATTTGCTCGATCATGACCCGCACCACATCGAGCGGTTTTTCCGCGCGGCTTACTCCAGC
GGCTTCACGCAGCGCCCCGACCTGACCATGATGGGCATCGTCAGCGGCTTGGAGATGGCCTGCTGGGACATCATCGGCAA
GGCCGCCGGCAAACCGGTGTATGAATTGATCGGCGGCCGTGTGCATGAGCGCCTGCGCACCTACACCTACCTCTATCCGA
AAAATGCCAAGGGCGAGCACGACTACGATGATGTGGACCTGTCGGTGGCATGCGCAGTGGACTTGGTGAAACAGGGTTTT
ACCGCCGTCAAGTTCGACCCGGCCGGGCCGTACAGCGTTTATTCCGGCCACCATCTGTCGCTGGAAGTGATGGACAAGTC
GGAAGAGTTCTGCAAGAAGATACGCGAGGCCGTCGGCAGCAAATGCGATTTGCTGTTCGGCACGCATGGACAGATGACCG
TGGCCTCGGCGGTGCGTCTGGCGCGGCGGCTGGAAAAATACGACCCGCTCTGGTTCGAAGAACCGGTGCCGCCGGGGCAG
GTCGATGCGATGGCAGCGGTCGCTGGCAAGACCTCCATTCCCATCGCCACGGGCGAGCGCCTGACCACCAAATATGAATT
CTTCGACTTGCTCCAGCGCGGCGGCGCCTCGATTCTGCAAATGAATCTGGGACGTGTCGGCGGCATTCTGGAAGCCAAGA
AAATCGCCGGCATCGCCGAAGTCCACTGTGCCCAGATCGCGCCGCATCTGTACAACGGCCCGGTCGGTGCGGCAGCCAGC
GTTCAGTTGGCAACCGCCACGCCCAACTTCCTGATTCAGGAAAGCATCATGACCTGGCAAGGCTTTCATGCCGAGATTCT
GAAGCAACCGATTCAGTGGGAGGACGGCTTCATCATCCCCTCGCGCGAGCCAGGTCTGGGGGTGGAGTTGAATATGGACG
TGGTGGAAGCCAATGCGCCCTATGTCGGCAGCCGGCTGCACATCACGATGGACCCCCAGCCTTTCGACGTCAAGCAGCCA
TCGAGCGATAGCTGGAAGAAGCGCTGGAGTGATGAGGTTGCGCGGTGA

Upstream 100 bases:

>100_bases
GCTACAAAATATATTTCGGCTACATCGTCGCCTGCGGATTGGGCGGCACGGCAGTCGCTTTCTACTTCAAAAACCTGACC
CAACGAGAAAAGGTGCAGCA

Downstream 100 bases:

>100_bases
ATGTCGACTTCATCATCGTCGGGGCGGGTTCGGCGGGCTGCATACTCGCCAACCGCTTGAGCGAATCGCACAGTGTATTG
CTGCTGGAAGCGGGCGGCAA

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKIISMKSHVVAVPPPYIGGMYWIFVTLKTACGIEGVGEIYASTFHPKVVACAMDDVFERHLLDHDPHHIERFFRAAYSS
GFTQRPDLTMMGIVSGLEMACWDIIGKAAGKPVYELIGGRVHERLRTYTYLYPKNAKGEHDYDDVDLSVACAVDLVKQGF
TAVKFDPAGPYSVYSGHHLSLEVMDKSEEFCKKIREAVGSKCDLLFGTHGQMTVASAVRLARRLEKYDPLWFEEPVPPGQ
VDAMAAVAGKTSIPIATGERLTTKYEFFDLLQRGGASILQMNLGRVGGILEAKKIAGIAEVHCAQIAPHLYNGPVGAAAS
VQLATATPNFLIQESIMTWQGFHAEILKQPIQWEDGFIIPSREPGLGVELNMDVVEANAPYVGSRLHITMDPQPFDVKQP
SSDSWKKRWSDEVAR

Sequences:

>Translated_415_residues
MKIISMKSHVVAVPPPYIGGMYWIFVTLKTACGIEGVGEIYASTFHPKVVACAMDDVFERHLLDHDPHHIERFFRAAYSS
GFTQRPDLTMMGIVSGLEMACWDIIGKAAGKPVYELIGGRVHERLRTYTYLYPKNAKGEHDYDDVDLSVACAVDLVKQGF
TAVKFDPAGPYSVYSGHHLSLEVMDKSEEFCKKIREAVGSKCDLLFGTHGQMTVASAVRLARRLEKYDPLWFEEPVPPGQ
VDAMAAVAGKTSIPIATGERLTTKYEFFDLLQRGGASILQMNLGRVGGILEAKKIAGIAEVHCAQIAPHLYNGPVGAAAS
VQLATATPNFLIQESIMTWQGFHAEILKQPIQWEDGFIIPSREPGLGVELNMDVVEANAPYVGSRLHITMDPQPFDVKQP
SSDSWKKRWSDEVAR
>Mature_415_residues
MKIISMKSHVVAVPPPYIGGMYWIFVTLKTACGIEGVGEIYASTFHPKVVACAMDDVFERHLLDHDPHHIERFFRAAYSS
GFTQRPDLTMMGIVSGLEMACWDIIGKAAGKPVYELIGGRVHERLRTYTYLYPKNAKGEHDYDDVDLSVACAVDLVKQGF
TAVKFDPAGPYSVYSGHHLSLEVMDKSEEFCKKIREAVGSKCDLLFGTHGQMTVASAVRLARRLEKYDPLWFEEPVPPGQ
VDAMAAVAGKTSIPIATGERLTTKYEFFDLLQRGGASILQMNLGRVGGILEAKKIAGIAEVHCAQIAPHLYNGPVGAAAS
VQLATATPNFLIQESIMTWQGFHAEILKQPIQWEDGFIIPSREPGLGVELNMDVVEANAPYVGSRLHITMDPQPFDVKQP
SSDSWKKRWSDEVAR

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=398, Percent_Identity=24.1206030150754, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI186972148, Length=323, Percent_Identity=23.8390092879257, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994953, Length=392, Percent_Identity=31.3775510204082, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787864, Length=388, Percent_Identity=27.8350515463918, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI226510960, Length=294, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 45856; Mature: 45856

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIISMKSHVVAVPPPYIGGMYWIFVTLKTACGIEGVGEIYASTFHPKVVACAMDDVFER
CEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHHHHHHH
HLLDHDPHHIERFFRAAYSSGFTQRPDLTMMGIVSGLEMACWDIIGKAAGKPVYELIGGR
HHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VHERLRTYTYLYPKNAKGEHDYDDVDLSVACAVDLVKQGFTAVKFDPAGPYSVYSGHHLS
HHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEE
LEVMDKSEEFCKKIREAVGSKCDLLFGTHGQMTVASAVRLARRLEKYDPLWFEEPVPPGQ
EEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
VDAMAAVAGKTSIPIATGERLTTKYEFFDLLQRGGASILQMNLGRVGGILEAKKIAGIAE
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHCCHHH
VHCAQIAPHLYNGPVGAAASVQLATATPNFLIQESIMTWQGFHAEILKQPIQWEDGFIIP
HHHHHHCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEC
SREPGLGVELNMDVVEANAPYVGSRLHITMDPQPFDVKQPSSDSWKKRWSDEVAR
CCCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIISMKSHVVAVPPPYIGGMYWIFVTLKTACGIEGVGEIYASTFHPKVVACAMDDVFER
CEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHHHHHHH
HLLDHDPHHIERFFRAAYSSGFTQRPDLTMMGIVSGLEMACWDIIGKAAGKPVYELIGGR
HHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VHERLRTYTYLYPKNAKGEHDYDDVDLSVACAVDLVKQGFTAVKFDPAGPYSVYSGHHLS
HHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEE
LEVMDKSEEFCKKIREAVGSKCDLLFGTHGQMTVASAVRLARRLEKYDPLWFEEPVPPGQ
EEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
VDAMAAVAGKTSIPIATGERLTTKYEFFDLLQRGGASILQMNLGRVGGILEAKKIAGIAE
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHCCHHH
VHCAQIAPHLYNGPVGAAASVQLATATPNFLIQESIMTWQGFHAEILKQPIQWEDGFIIP
HHHHHHCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEC
SREPGLGVELNMDVVEANAPYVGSRLHITMDPQPFDVKQPSSDSWKKRWSDEVAR
CCCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA