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The map label for this gene is betA [H]

Identifier: 121609857

GI number: 121609857

Start: 3258129

End: 3259736

Strand: Direct

Name: betA [H]

Synonym: Veis_2910

Alternate gene names: 121609857

Gene position: 3258129-3259736 (Clockwise)

Preceding gene: 121609856

Following gene: 121609866

Centisome position: 58.53

GC content: 62.31

Gene sequence:

>1608_bases
GTGAATGTCGACTTCATCATCGTCGGGGCGGGTTCGGCGGGCTGCATACTCGCCAACCGCTTGAGCGAATCGCACAGTGT
ATTGCTGCTGGAAGCGGGCGGCAAGGATGACTCATGGTGGCTCAAACTGCCGCTCGGCTTTGTCAAGACGTACTACGACC
CGCGCTACAACTGGATGTATTACAGCGAGCCGGAGGCGGAGATGGCCGGGCGCCGCCTGTATGCGCCGCGCGGCAAAGTG
ATCGGCGGCTCCGGCGCGATCAATGCCATGATCCATGTGCGCGGCCAGCCGCGCGATTTCGACGACTGGGAGGCGGCGGG
CAACCCCGGTTGGGGTTATCGCGAGGTGCTGCCTTATTTCAAAAAGATGGAATCGCATCCGCTCGGTGAAACCCCCTGGC
ATGGCGGCGACGGCCCGATGGGCATCACGCCGATGAAGCAGGGCGCGCATCCGATGTGCCGGGCTTATCTGCAAGCCTGC
CAGCAAGCGGGTTACCCGCTCAATGAAGATTTCAACGGCGCGCATTTTGAAGGCGCCGGCATCTATGAAGCCAGCATCCG
CAACGGCAAGCGCGATTCCAGCGCGGTTGCGTACCTGCATCCAGCCCTGGGGCGCAGTCGTTTGCAGGTCGAGACCGAGG
CGCAGGTCGCACAGATTCTGTTCGATGGCCAGCAGTGCGCCCATGGCGTGCTGGTGCGTCAGCGCGGCCAGTTGCGCCGC
TTTTACGCCCATCGTGAAGTCATTCTTGCCGCCGGCGCGGTGGATACGCCGAAGCTGTTGCAACTGTCCGGCATTGGCGC
GGCTGCATTGCTGGCGCGCCACGGGATTGCGCTGCGCCATCATTTGCCGGCGGTTGGCCGCCATTTGCAGGATCATTTAT
GCGCATCCTTTTACTTTCGCGCCAGGTGCAAGACCCTCAATGATGAATTGGGCACGTGGCATGGGCAACTGGCGGCGGGC
ATGCAATACCTGTTCAAGCGCAGCGGCCCCTTGGCGATGAGCGTCAATCAGGCGGGCGGATTTTTCAAGGGCAGCGCGCT
GGAGCGGGAGCCAAACATTCAGTTGTATTTCAATCCGCTGTCCTACACGATTCCGAAAGACCCCAAGGCCAAACTGAAGC
CCGACCCTTGGTCGGGCTTCCTGCTGGCCTACAACCCGTGCCGTCCCGACAGTCGCGGCAGCATTGAAATTGCCGCCGCA
GATGCAGACCTGCCGGCAGCGATACGCCCCAATTACCTGAGCACCCCAAAGGACAGGGACGAAGCGGTACAAGGCGCGCG
CCTGATTCGTGCACTGAGCCAGGCGCCGGCCTTGCGCGCATTGATCGTGGAAGAAGTCAGCCCGGCAGGCGCGGTGACGG
ATGAGGCCGGCATGTTGCAGTTCTTCCGCGAGCAGGCGGGTTCCATCTACCACCTGTGCGGCTCTTGCGCAATGGGGCCG
GACGCCGCCACGGCAGTGGTCAACGCCGAGTTGAAGGTGCACGGTGTGCAGCGCTTGCGGGTTGTCGATGCCTCGGTGTT
TCCGAACATCACTTCAGGCAACATCAACGCTGCCACGATGATGGTGGCGGAGAAGGGGGCGGCGATGATTCTCGGGGAGT
ATCGCTGA

Upstream 100 bases:

>100_bases
TCGGCAGCCGGCTGCACATCACGATGGACCCCCAGCCTTTCGACGTCAAGCAGCCATCGAGCGATAGCTGGAAGAAGCGC
TGGAGTGATGAGGTTGCGCG

Downstream 100 bases:

>100_bases
CCGTAGCCGCTGCGGCGCCGGGTGGGGCCGGACTCCCGTTGCGTCAGAGCAACCCTGCCTCTTCGAGATAACTCTTGGCC
ACGGCTTCGATCGGCTTTCT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MNVDFIIVGAGSAGCILANRLSESHSVLLLEAGGKDDSWWLKLPLGFVKTYYDPRYNWMYYSEPEAEMAGRRLYAPRGKV
IGGSGAINAMIHVRGQPRDFDDWEAAGNPGWGYREVLPYFKKMESHPLGETPWHGGDGPMGITPMKQGAHPMCRAYLQAC
QQAGYPLNEDFNGAHFEGAGIYEASIRNGKRDSSAVAYLHPALGRSRLQVETEAQVAQILFDGQQCAHGVLVRQRGQLRR
FYAHREVILAAGAVDTPKLLQLSGIGAAALLARHGIALRHHLPAVGRHLQDHLCASFYFRARCKTLNDELGTWHGQLAAG
MQYLFKRSGPLAMSVNQAGGFFKGSALEREPNIQLYFNPLSYTIPKDPKAKLKPDPWSGFLLAYNPCRPDSRGSIEIAAA
DADLPAAIRPNYLSTPKDRDEAVQGARLIRALSQAPALRALIVEEVSPAGAVTDEAGMLQFFREQAGSIYHLCGSCAMGP
DAATAVVNAELKVHGVQRLRVVDASVFPNITSGNINAATMMVAEKGAAMILGEYR

Sequences:

>Translated_535_residues
MNVDFIIVGAGSAGCILANRLSESHSVLLLEAGGKDDSWWLKLPLGFVKTYYDPRYNWMYYSEPEAEMAGRRLYAPRGKV
IGGSGAINAMIHVRGQPRDFDDWEAAGNPGWGYREVLPYFKKMESHPLGETPWHGGDGPMGITPMKQGAHPMCRAYLQAC
QQAGYPLNEDFNGAHFEGAGIYEASIRNGKRDSSAVAYLHPALGRSRLQVETEAQVAQILFDGQQCAHGVLVRQRGQLRR
FYAHREVILAAGAVDTPKLLQLSGIGAAALLARHGIALRHHLPAVGRHLQDHLCASFYFRARCKTLNDELGTWHGQLAAG
MQYLFKRSGPLAMSVNQAGGFFKGSALEREPNIQLYFNPLSYTIPKDPKAKLKPDPWSGFLLAYNPCRPDSRGSIEIAAA
DADLPAAIRPNYLSTPKDRDEAVQGARLIRALSQAPALRALIVEEVSPAGAVTDEAGMLQFFREQAGSIYHLCGSCAMGP
DAATAVVNAELKVHGVQRLRVVDASVFPNITSGNINAATMMVAEKGAAMILGEYR
>Mature_535_residues
MNVDFIIVGAGSAGCILANRLSESHSVLLLEAGGKDDSWWLKLPLGFVKTYYDPRYNWMYYSEPEAEMAGRRLYAPRGKV
IGGSGAINAMIHVRGQPRDFDDWEAAGNPGWGYREVLPYFKKMESHPLGETPWHGGDGPMGITPMKQGAHPMCRAYLQAC
QQAGYPLNEDFNGAHFEGAGIYEASIRNGKRDSSAVAYLHPALGRSRLQVETEAQVAQILFDGQQCAHGVLVRQRGQLRR
FYAHREVILAAGAVDTPKLLQLSGIGAAALLARHGIALRHHLPAVGRHLQDHLCASFYFRARCKTLNDELGTWHGQLAAG
MQYLFKRSGPLAMSVNQAGGFFKGSALEREPNIQLYFNPLSYTIPKDPKAKLKPDPWSGFLLAYNPCRPDSRGSIEIAAA
DADLPAAIRPNYLSTPKDRDEAVQGARLIRALSQAPALRALIVEEVSPAGAVTDEAGMLQFFREQAGSIYHLCGSCAMGP
DAATAVVNAELKVHGVQRLRVVDASVFPNITSGNINAATMMVAEKGAAMILGEYR

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=542, Percent_Identity=40.9594095940959, Blast_Score=377, Evalue=1e-104,
Organism=Escherichia coli, GI1786503, Length=543, Percent_Identity=39.0423572744015, Blast_Score=349, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17532301, Length=552, Percent_Identity=34.963768115942, Blast_Score=305, Evalue=6e-83,
Organism=Drosophila melanogaster, GI24642039, Length=565, Percent_Identity=35.3982300884956, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24642055, Length=572, Percent_Identity=34.0909090909091, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24650267, Length=569, Percent_Identity=34.4463971880492, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI17137792, Length=560, Percent_Identity=36.0714285714286, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24642048, Length=571, Percent_Identity=33.6252189141856, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24642042, Length=574, Percent_Identity=33.2752613240418, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24642059, Length=575, Percent_Identity=33.3913043478261, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI45549471, Length=573, Percent_Identity=32.9842931937173, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI18859995, Length=563, Percent_Identity=35.1687388987567, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI45551458, Length=569, Percent_Identity=33.2161687170475, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24642037, Length=581, Percent_Identity=33.2185886402754, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24642051, Length=572, Percent_Identity=32.3426573426573, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24642035, Length=580, Percent_Identity=31.8965517241379, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI18859993, Length=571, Percent_Identity=31.8739054290718, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24642057, Length=595, Percent_Identity=28.4033613445378, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 58298; Mature: 58298

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDFIIVGAGSAGCILANRLSESHSVLLLEAGGKDDSWWLKLPLGFVKTYYDPRYNWMY
CCCEEEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEECHHHHHHHCCCCCCEEE
YSEPEAEMAGRRLYAPRGKVIGGSGAINAMIHVRGQPRDFDDWEAAGNPGWGYREVLPYF
ECCCCHHHCCCEEECCCCCEEECCCCEEEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHH
KKMESHPLGETPWHGGDGPMGITPMKQGAHPMCRAYLQACQQAGYPLNEDFNGAHFEGAG
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCC
IYEASIRNGKRDSSAVAYLHPALGRSRLQVETEAQVAQILFDGQQCAHGVLVRQRGQLRR
EEEHHHCCCCCCCCEEEEEEHHCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FYAHREVILAAGAVDTPKLLQLSGIGAAALLARHGIALRHHLPAVGRHLQDHLCASFYFR
HHHHCEEEEEECCCCCCHHEEECCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
ARCKTLNDELGTWHGQLAAGMQYLFKRSGPLAMSVNQAGGFFKGSALEREPNIQLYFNPL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCEEEEECCE
SYTIPKDPKAKLKPDPWSGFLLAYNPCRPDSRGSIEIAAADADLPAAIRPNYLSTPKDRD
EEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHH
EAVQGARLIRALSQAPALRALIVEEVSPAGAVTDEAGMLQFFREQAGSIYHLCGSCAMGP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEHHHCCCCCC
DAATAVVNAELKVHGVQRLRVVDASVFPNITSGNINAATMMVAEKGAAMILGEYR
CCEEEEEECEEEEECEEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCEEEEECCC
>Mature Secondary Structure
MNVDFIIVGAGSAGCILANRLSESHSVLLLEAGGKDDSWWLKLPLGFVKTYYDPRYNWMY
CCCEEEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEECHHHHHHHCCCCCCEEE
YSEPEAEMAGRRLYAPRGKVIGGSGAINAMIHVRGQPRDFDDWEAAGNPGWGYREVLPYF
ECCCCHHHCCCEEECCCCCEEECCCCEEEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHH
KKMESHPLGETPWHGGDGPMGITPMKQGAHPMCRAYLQACQQAGYPLNEDFNGAHFEGAG
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCC
IYEASIRNGKRDSSAVAYLHPALGRSRLQVETEAQVAQILFDGQQCAHGVLVRQRGQLRR
EEEHHHCCCCCCCCEEEEEEHHCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FYAHREVILAAGAVDTPKLLQLSGIGAAALLARHGIALRHHLPAVGRHLQDHLCASFYFR
HHHHCEEEEEECCCCCCHHEEECCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
ARCKTLNDELGTWHGQLAAGMQYLFKRSGPLAMSVNQAGGFFKGSALEREPNIQLYFNPL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCEEEEECCE
SYTIPKDPKAKLKPDPWSGFLLAYNPCRPDSRGSIEIAAADADLPAAIRPNYLSTPKDRD
EEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHH
EAVQGARLIRALSQAPALRALIVEEVSPAGAVTDEAGMLQFFREQAGSIYHLCGSCAMGP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEHHHCCCCCC
DAATAVVNAELKVHGVQRLRVVDASVFPNITSGNINAATMMVAEKGAAMILGEYR
CCEEEEEECEEEEECEEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA