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The map label for this gene is fabF [C]

Identifier: 121609492

GI number: 121609492

Start: 2866263

End: 2867831

Strand: Direct

Name: fabF [C]

Synonym: Veis_2536

Alternate gene names: 121609492

Gene position: 2866263-2867831 (Clockwise)

Preceding gene: 121609482

Following gene: 121609493

Centisome position: 51.49

GC content: 60.36

Gene sequence:

>1569_bases
ATGGGATGCCATGAGCGTTCAGATCGAAGCCTTGTTCACCGCTACGCCGGGTCTTCTACAAAGGCCGAGATCGTTGCGCC
CACGTCCTACAAGCCTCGCAACGTGGTAATCACAGGCGTGGGTGCCGTGTCCTCTGCGGGGTTCGGCCGGGCCGAGATGT
TCGATAACATCCATGCGGGCGGGACGTTCTCCTCCAAGGTGTCTGTCGGTGGCACAGGGCTGGACGAGGATCAGAAGTTG
AAATTTGCTGGCTGGCTCAGCAGAAGCCCCCAGTTGATCGAGACCTTGTCGAAGCTGCCATCGAACTCGTCGGGCGAGAT
CGAGTTGCGGGTTCACAGCATCGACGATGAGCAACTCAAGAAGCAGTTGAGAAATTCCAACGACAGAAAAGCCAGCAAGA
TCGGCAAGATTGCCTTGCTGGCAGTCGACATGGCCCTGTCCGACGGAGGCCGGAAAATCCGGCGCGACGGACAAGACATT
GCCCTGATCTTCGGCATGTCGAAGGGCCCGCATTCCACGGTCGCGCGTTTCGTGAGCAGTCTACATCCCGACCCCAAGCA
CATCAGGACCCTGGACTTCCCAGGATCGCTCATGAATGCAGTGGCCACTTACTGCTCGATCTCGAAAGGCATTCGCGGTT
ACAACACGACGCTCGCCACTGGCTTCAATTCCGGCTTGGGCGCGTTGACCTATGGCTATGAGCTCATCCGTCAAGGCGTC
CAGCCGCAGGCCATCGTTGGGGGGGCGGACGAGAGCTTCATCGGCACTTCGACCTTGCTTGCCGACCCCAACAATCAAGT
CAACTACGACCTGGCGGAGGACGCCTTCAAGACCTACGGCCGCGATCACGGCGGCCTTCATGTGGGAGAGGGCGCCTGCA
TGGTGCTCCTCGAGGACGAGGAAGTGGCCCGGCAGCGAGGCGCCAAGGTCCTCGGGCGGCTGCTAGTGTCGCGTCACCGA
TCATCTGTCGGTCTGCGCTGGCCATCGAAGCGCATCGCGGCGTTGCATCGCTTGCCAATACGCTCGGTATTGGCTGCGCG
ATGCGCCTTGCGCTGCGCTCCGATGGCTGCGCGCAGCCTACGACATCTGATCCGTGACGCGACACTAGGGTATGGCGTGT
CGAACGACGTCTCGTACTTCCGGGGCGAAGACGAGGATGCGTCGCCGAAGATGATGGAACGGGCGATTCGGCAAGCGCTG
GTCGAAGCCGCAGTCTCGCCCGATCAAGTGAACCTGCTGTGTGGTTCAAGCTGGGGCACCAAGAGCAGCAGCATGAAAGA
GCTAGAAGCGATTCGCCGGGTCTTCGGCGAGCGCGCCTCCTCGATTCCTCTGATCAATCACAACGGATACTTCGGCTTTG
TCGAATCTGCAGCCGCGCTGTTGAATCTGGCCATGGTGCTGACCTCCGCTGAGAGAGGGCAGATCCTTCCTCTGGGGCAC
ACCAAGGACTTCTGCCAGGCCGGGTTCGATTTCGTCACGGACAAGCGCCCGCACAAGTTCTCGAAAGCCCTGTTGATGGG
TGCCACAGAGGGTGGTGGGAACTACGCCGTCGTCCTGGGGACAGAATGA

Upstream 100 bases:

>100_bases
TGCAGACTTGTGACTTGTTCAGCGTAGCCTTGAAACTGTCAGTCGTAGGTGAGCCCTGTGGGCATGCTGCATTTGAGCCT
GCCCACAGCGCGATTTTGGA

Downstream 100 bases:

>100_bases
CATCGTCCATTGCCGCCAGTAATGTTCACATCGCAGGGTTTGGCGTCGAGACAGGCCTGGGCTTCGGTCATGCCCGCCTG
CTACAGTCGATCGAGAACAG

Product: beta-ketoacyl synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: None

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MGCHERSDRSLVHRYAGSSTKAEIVAPTSYKPRNVVITGVGAVSSAGFGRAEMFDNIHAGGTFSSKVSVGGTGLDEDQKL
KFAGWLSRSPQLIETLSKLPSNSSGEIELRVHSIDDEQLKKQLRNSNDRKASKIGKIALLAVDMALSDGGRKIRRDGQDI
ALIFGMSKGPHSTVARFVSSLHPDPKHIRTLDFPGSLMNAVATYCSISKGIRGYNTTLATGFNSGLGALTYGYELIRQGV
QPQAIVGGADESFIGTSTLLADPNNQVNYDLAEDAFKTYGRDHGGLHVGEGACMVLLEDEEVARQRGAKVLGRLLVSRHR
SSVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSLRHLIRDATLGYGVSNDVSYFRGEDEDASPKMMERAIRQAL
VEAAVSPDQVNLLCGSSWGTKSSSMKELEAIRRVFGERASSIPLINHNGYFGFVESAAALLNLAMVLTSAERGQILPLGH
TKDFCQAGFDFVTDKRPHKFSKALLMGATEGGGNYAVVLGTE

Sequences:

>Translated_522_residues
MGCHERSDRSLVHRYAGSSTKAEIVAPTSYKPRNVVITGVGAVSSAGFGRAEMFDNIHAGGTFSSKVSVGGTGLDEDQKL
KFAGWLSRSPQLIETLSKLPSNSSGEIELRVHSIDDEQLKKQLRNSNDRKASKIGKIALLAVDMALSDGGRKIRRDGQDI
ALIFGMSKGPHSTVARFVSSLHPDPKHIRTLDFPGSLMNAVATYCSISKGIRGYNTTLATGFNSGLGALTYGYELIRQGV
QPQAIVGGADESFIGTSTLLADPNNQVNYDLAEDAFKTYGRDHGGLHVGEGACMVLLEDEEVARQRGAKVLGRLLVSRHR
SSVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSLRHLIRDATLGYGVSNDVSYFRGEDEDASPKMMERAIRQAL
VEAAVSPDQVNLLCGSSWGTKSSSMKELEAIRRVFGERASSIPLINHNGYFGFVESAAALLNLAMVLTSAERGQILPLGH
TKDFCQAGFDFVTDKRPHKFSKALLMGATEGGGNYAVVLGTE
>Mature_521_residues
GCHERSDRSLVHRYAGSSTKAEIVAPTSYKPRNVVITGVGAVSSAGFGRAEMFDNIHAGGTFSSKVSVGGTGLDEDQKLK
FAGWLSRSPQLIETLSKLPSNSSGEIELRVHSIDDEQLKKQLRNSNDRKASKIGKIALLAVDMALSDGGRKIRRDGQDIA
LIFGMSKGPHSTVARFVSSLHPDPKHIRTLDFPGSLMNAVATYCSISKGIRGYNTTLATGFNSGLGALTYGYELIRQGVQ
PQAIVGGADESFIGTSTLLADPNNQVNYDLAEDAFKTYGRDHGGLHVGEGACMVLLEDEEVARQRGAKVLGRLLVSRHRS
SVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSLRHLIRDATLGYGVSNDVSYFRGEDEDASPKMMERAIRQALV
EAAVSPDQVNLLCGSSWGTKSSSMKELEAIRRVFGERASSIPLINHNGYFGFVESAAALLNLAMVLTSAERGQILPLGHT
KDFCQAGFDFVTDKRPHKFSKALLMGATEGGGNYAVVLGTE

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 56249; Mature: 56118

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCHERSDRSLVHRYAGSSTKAEIVAPTSYKPRNVVITGVGAVSSAGFGRAEMFDNIHAG
CCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCC
GTFSSKVSVGGTGLDEDQKLKFAGWLSRSPQLIETLSKLPSNSSGEIELRVHSIDDEQLK
CCCCCEEECCCCCCCCCCCEEEEHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHH
KQLRNSNDRKASKIGKIALLAVDMALSDGGRKIRRDGQDIALIFGMSKGPHSTVARFVSS
HHHHCCCCHHHHHHCCEEEEEEEHHHCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
LHPDPKHIRTLDFPGSLMNAVATYCSISKGIRGYNTTLATGFNSGLGALTYGYELIRQGV
HCCCHHHEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCC
QPQAIVGGADESFIGTSTLLADPNNQVNYDLAEDAFKTYGRDHGGLHVGEGACMVLLEDE
CCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEEECCH
EVARQRGAKVLGRLLVSRHRSSVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RHLIRDATLGYGVSNDVSYFRGEDEDASPKMMERAIRQALVEAAVSPDQVNLLCGSSWGT
HHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
KSSSMKELEAIRRVFGERASSIPLINHNGYFGFVESAAALLNLAMVLTSAERGQILPLGH
CCHHHHHHHHHHHHHHCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCC
TKDFCQAGFDFVTDKRPHKFSKALLMGATEGGGNYAVVLGTE
CHHHHHCCCHHHCCCCCHHHHHHHHEECCCCCCCEEEEEECC
>Mature Secondary Structure 
GCHERSDRSLVHRYAGSSTKAEIVAPTSYKPRNVVITGVGAVSSAGFGRAEMFDNIHAG
CCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCC
GTFSSKVSVGGTGLDEDQKLKFAGWLSRSPQLIETLSKLPSNSSGEIELRVHSIDDEQLK
CCCCCEEECCCCCCCCCCCEEEEHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHH
KQLRNSNDRKASKIGKIALLAVDMALSDGGRKIRRDGQDIALIFGMSKGPHSTVARFVSS
HHHHCCCCHHHHHHCCEEEEEEEHHHCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
LHPDPKHIRTLDFPGSLMNAVATYCSISKGIRGYNTTLATGFNSGLGALTYGYELIRQGV
HCCCHHHEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCC
QPQAIVGGADESFIGTSTLLADPNNQVNYDLAEDAFKTYGRDHGGLHVGEGACMVLLEDE
CCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEEECCH
EVARQRGAKVLGRLLVSRHRSSVGLRWPSKRIAALHRLPIRSVLAARCALRCAPMAARSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RHLIRDATLGYGVSNDVSYFRGEDEDASPKMMERAIRQALVEAAVSPDQVNLLCGSSWGT
HHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
KSSSMKELEAIRRVFGERASSIPLINHNGYFGFVESAAALLNLAMVLTSAERGQILPLGH
CCHHHHHHHHHHHHHHCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCC
TKDFCQAGFDFVTDKRPHKFSKALLMGATEGGGNYAVVLGTE
CHHHHHCCCHHHCCCCCHHHHHHHHEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA