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The map label for this gene is insF1 [C]

Identifier: 121609482

GI number: 121609482

Start: 2855717

End: 2856565

Strand: Direct

Name: insF1 [C]

Synonym: Veis_2526

Alternate gene names: 121609482

Gene position: 2855717-2856565 (Clockwise)

Preceding gene: 121609481

Following gene: 121609492

Centisome position: 51.3

GC content: 65.25

Gene sequence:

>849_bases
GTGCAGTGCCGAGTCCTGCAGGCCAGCATCACCGGCTACCACGAACACTTCGTTCGTAGAGCCAGCGCGGCCCAGCGGCA
CCATCTCAGCGACGACGCGCTGCTGGTGCACATCGAGGTGATCCACGCCGAAACGCGGGGCGGCTACGGCTGGCCGCGCA
CGTGGAAGGAACTGCTGGCCAGGGGCATCCGGGTGGGCAAGGAGCGGGTGCGCAAGCTCATGCAACTGCACGGCATCCGG
GCCAAGGGCAAGCGCCGCTTGAAGGTCACCACGGACAGCAAGCATGACCTGCCGATCGCCCCCAATCTGCTGGATCGGCA
GTTCGATGTGGCCGAACCCGACAAGGTCTGGGTGGGCGACATCACCTACATCGCAACCGACGAAGGCTGGCTGTTGCTGG
CCGTGGTGATCGACCTGTTCAGCCGCCAGGTGGTGGGCTGGTCACTGCGCCAGGACATGACGCGCGACATCGTCATCGAT
GCTGTGCGCATGGCCTGGTTCAAGCGCCATCCGCGCAAGCATGCCGGGCTGATCTTGCACAGCGACCGGGGCAGCCAATA
CGCCAGCGAGGACTTCAGGGACGTGCTCGCCCAGTGCGGCATCACGGCCTCGATGAGCCGCAAGGGCAACTGCTGGGACA
ACGCCTGCAGCGAGACCCTGTTCGGTTCGTTGAAGGTGGAGCGACTGCATGGGCAGCGCTTCGTGACGCGGCGCCAGGCC
AAGGACGAGGTCATCGCCTGGGTACTCTGGTACAACCGCACCCGGCTGCACTCCACGCTGGCGTACGTCAGCCCGGTGCG
GTTCGAGCAAGACTGGTATGCGGCTCAGGCCAAGCAAGCCAATTCGTGA

Upstream 100 bases:

>100_bases
TGGAGCGTGACATCCTGGGAAAAGCGACGGCGTACTTCGCGAAGGCGCACACCTGAAGTACGCCTTCATTCACCGCAACC
GCCAGGCGTGGCCGATCTCG

Downstream 100 bases:

>100_bases
CTCCGCTATGGGGTACGGATTCCAGGGGCAAGGTCAATGAGCCTGAATGCAGGGGCCACGAGAGATGATTCAGGCGGCTT
CTTTGGGTCGTCGGTTGAAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQCRVLQASITGYHEHFVRRASAAQRHHLSDDALLVHIEVIHAETRGGYGWPRTWKELLARGIRVGKERVRKLMQLHGIR
AKGKRRLKVTTDSKHDLPIAPNLLDRQFDVAEPDKVWVGDITYIATDEGWLLLAVVIDLFSRQVVGWSLRQDMTRDIVID
AVRMAWFKRHPRKHAGLILHSDRGSQYASEDFRDVLAQCGITASMSRKGNCWDNACSETLFGSLKVERLHGQRFVTRRQA
KDEVIAWVLWYNRTRLHSTLAYVSPVRFEQDWYAAQAKQANS

Sequences:

>Translated_282_residues
MQCRVLQASITGYHEHFVRRASAAQRHHLSDDALLVHIEVIHAETRGGYGWPRTWKELLARGIRVGKERVRKLMQLHGIR
AKGKRRLKVTTDSKHDLPIAPNLLDRQFDVAEPDKVWVGDITYIATDEGWLLLAVVIDLFSRQVVGWSLRQDMTRDIVID
AVRMAWFKRHPRKHAGLILHSDRGSQYASEDFRDVLAQCGITASMSRKGNCWDNACSETLFGSLKVERLHGQRFVTRRQA
KDEVIAWVLWYNRTRLHSTLAYVSPVRFEQDWYAAQAKQANS
>Mature_282_residues
MQCRVLQASITGYHEHFVRRASAAQRHHLSDDALLVHIEVIHAETRGGYGWPRTWKELLARGIRVGKERVRKLMQLHGIR
AKGKRRLKVTTDSKHDLPIAPNLLDRQFDVAEPDKVWVGDITYIATDEGWLLLAVVIDLFSRQVVGWSLRQDMTRDIVID
AVRMAWFKRHPRKHAGLILHSDRGSQYASEDFRDVLAQCGITASMSRKGNCWDNACSETLFGSLKVERLHGQRFVTRRQA
KDEVIAWVLWYNRTRLHSTLAYVSPVRFEQDWYAAQAKQANS

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=244, Percent_Identity=34.4262295081967, Blast_Score=134, Evalue=7e-32,
Organism=Escherichia coli, GI1788405, Length=272, Percent_Identity=40.8088235294118, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787263, Length=272, Percent_Identity=40.8088235294118, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786753, Length=272, Percent_Identity=40.8088235294118, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786570, Length=272, Percent_Identity=40.8088235294118, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786490, Length=272, Percent_Identity=40.8088235294118, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789981, Length=242, Percent_Identity=33.4710743801653, Blast_Score=140, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32547; Mature: 32547

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCRVLQASITGYHEHFVRRASAAQRHHLSDDALLVHIEVIHAETRGGYGWPRTWKELLA
CCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHH
RGIRVGKERVRKLMQLHGIRAKGKRRLKVTTDSKHDLPIAPNLLDRQFDVAEPDKVWVGD
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCEEECC
ITYIATDEGWLLLAVVIDLFSRQVVGWSLRQDMTRDIVIDAVRMAWFKRHPRKHAGLILH
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SDRGSQYASEDFRDVLAQCGITASMSRKGNCWDNACSETLFGSLKVERLHGQRFVTRRQA
CCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KDEVIAWVLWYNRTRLHSTLAYVSPVRFEQDWYAAQAKQANS
HHHHEEEEEHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MQCRVLQASITGYHEHFVRRASAAQRHHLSDDALLVHIEVIHAETRGGYGWPRTWKELLA
CCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHH
RGIRVGKERVRKLMQLHGIRAKGKRRLKVTTDSKHDLPIAPNLLDRQFDVAEPDKVWVGD
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCEEECC
ITYIATDEGWLLLAVVIDLFSRQVVGWSLRQDMTRDIVIDAVRMAWFKRHPRKHAGLILH
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SDRGSQYASEDFRDVLAQCGITASMSRKGNCWDNACSETLFGSLKVERLHGQRFVTRRQA
CCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KDEVIAWVLWYNRTRLHSTLAYVSPVRFEQDWYAAQAKQANS
HHHHEEEEEHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]