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The map label for this gene is fabF [C]

Identifier: 121609493

GI number: 121609493

Start: 2867828

End: 2869117

Strand: Direct

Name: fabF [C]

Synonym: Veis_2537

Alternate gene names: 121609493

Gene position: 2867828-2869117 (Clockwise)

Preceding gene: 121609492

Following gene: 121609494

Centisome position: 51.52

GC content: 62.33

Gene sequence:

>1290_bases
ATGACATCGTCCATTGCCGCCAGTAATGTTCACATCGCAGGGTTTGGCGTCGAGACAGGCCTGGGCTTCGGTCATGCCCG
CCTGCTACAGTCGATCGAGAACAGTGAATCGGCTGCAAGGCGGGGCTTCTTCGGCAAGCCCTTCGAGGCGGGCATGGCCG
GCTTCGGCTTCAATCCCCAGGTCGTGTCGCTCTCCGCCCCCGCCAAGAAGTCCAATGGCGGATACCACCAGGCACTCGCC
AAGGACGTGGCCGGCATCACGCGGAAGGTGATCGTCGATGCCCTGGACAGTGCGTCGATCCCCACCGACTCCCTGACGCA
CAAGCGAGTCTGCGTCTTTTACGGCGGACCGGGCATGCTGCCGGAGATCGCCAACTTTCTGCCCTACATCCGAAGGAACG
ACAAGAACGACATCTCGTTTCACCGGGGCATTCGCAACCTCACCTTCGAGAACCACAATCAGGACGCGGTCGCCCGGCTG
CTGCGCGATGGACTTGGCCTGAGGGAGCGACCCATCTCGGTATATTCGGCGAGCTGCTCCAGCTTCGCCGCAGCCTACTT
GGCGTATTGCTCTGTCAAGTCGCACACATGCGACTTGGCGATCGCCGTTTCTTTCCAGCATGTCTCCCTGTTCGACCTCA
TGTTCATGAACGGCTTTGGCGGTGTCGCTGCCGGAAGATCCGGCCCCTTCTCGGCGAACGGAGAAGGGACAGTCCTGGGC
GATGGCGCATGCGCCATGGTACTGGAATCCCCGGCTCACCTTCACGCCAGAAAGGGCACGCCCTACGCCTCGATGGACAG
CATGGTCATGCGCCAGAGCGCGGGCACCGTGAGCCGCAGCACGACATTCACGCCGGACTTCCGAGTCATCGGTCGGACGA
TCGCCAAGGCGATGGAAGACGCCAACGGCCTCGGCGCGAACGACATCGCCTGCGTCTTCCCGCATGGCAACGGGATACGT
TCCAGCGACCGCTCCGAGGCTTTGGCGCTTCAAAAAGTCTGGGGAGCGCTGGACACGCCCGTCGTCTCCTACAAGGCCCA
GATCGGCTACCTGATGGCTTCGAGCGCACTGGTCGACATGGCGCTCATGAGCGGATTCCTGGGCTCGGGTTCGCTACCTG
CGTTCAAGTGCGAAGGAGAGGTCGATGCCGGCCTGGGCATCAACCTGCATGCCAACAAATCCGCGTACCGCTTGTCAGGC
AACGCTGGCGTCAAGATCGGGCTTGGAATCGAAGGATCCGTCGGTGCCGCAGTCATCCGTTCCCTGCGTTGGCGGAGGCG
CTCGCCATGA

Upstream 100 bases:

>100_bases
TCGATTTCGTCACGGACAAGCGCCCGCACAAGTTCTCGAAAGCCCTGTTGATGGGTGCCACAGAGGGTGGTGGGAACTAC
GCCGTCGTCCTGGGGACAGA

Downstream 100 bases:

>100_bases
CGACACCCATCGAAAGGCGCAATGACCACCCAGCGTCGGCGGGCGCCCGGCGCCTGGGCGTTTACGGCTTGTCGGTCGTC
GAACCCGACCCTCGCCACAT

Product: beta-ketoacyl synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: Beta-Ketoacyl Synthase C-Domain Protein; 3-Oxoacyl-(Acyl Carrier Protein) Synthase II N-Terminal; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase Beta Chain; Beta-Ketoacyl-ACP Synthase

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTSSIAASNVHIAGFGVETGLGFGHARLLQSIENSESAARRGFFGKPFEAGMAGFGFNPQVVSLSAPAKKSNGGYHQALA
KDVAGITRKVIVDALDSASIPTDSLTHKRVCVFYGGPGMLPEIANFLPYIRRNDKNDISFHRGIRNLTFENHNQDAVARL
LRDGLGLRERPISVYSASCSSFAAAYLAYCSVKSHTCDLAIAVSFQHVSLFDLMFMNGFGGVAAGRSGPFSANGEGTVLG
DGACAMVLESPAHLHARKGTPYASMDSMVMRQSAGTVSRSTTFTPDFRVIGRTIAKAMEDANGLGANDIACVFPHGNGIR
SSDRSEALALQKVWGALDTPVVSYKAQIGYLMASSALVDMALMSGFLGSGSLPAFKCEGEVDAGLGINLHANKSAYRLSG
NAGVKIGLGIEGSVGAAVIRSLRWRRRSP

Sequences:

>Translated_429_residues
MTSSIAASNVHIAGFGVETGLGFGHARLLQSIENSESAARRGFFGKPFEAGMAGFGFNPQVVSLSAPAKKSNGGYHQALA
KDVAGITRKVIVDALDSASIPTDSLTHKRVCVFYGGPGMLPEIANFLPYIRRNDKNDISFHRGIRNLTFENHNQDAVARL
LRDGLGLRERPISVYSASCSSFAAAYLAYCSVKSHTCDLAIAVSFQHVSLFDLMFMNGFGGVAAGRSGPFSANGEGTVLG
DGACAMVLESPAHLHARKGTPYASMDSMVMRQSAGTVSRSTTFTPDFRVIGRTIAKAMEDANGLGANDIACVFPHGNGIR
SSDRSEALALQKVWGALDTPVVSYKAQIGYLMASSALVDMALMSGFLGSGSLPAFKCEGEVDAGLGINLHANKSAYRLSG
NAGVKIGLGIEGSVGAAVIRSLRWRRRSP
>Mature_428_residues
TSSIAASNVHIAGFGVETGLGFGHARLLQSIENSESAARRGFFGKPFEAGMAGFGFNPQVVSLSAPAKKSNGGYHQALAK
DVAGITRKVIVDALDSASIPTDSLTHKRVCVFYGGPGMLPEIANFLPYIRRNDKNDISFHRGIRNLTFENHNQDAVARLL
RDGLGLRERPISVYSASCSSFAAAYLAYCSVKSHTCDLAIAVSFQHVSLFDLMFMNGFGGVAAGRSGPFSANGEGTVLGD
GACAMVLESPAHLHARKGTPYASMDSMVMRQSAGTVSRSTTFTPDFRVIGRTIAKAMEDANGLGANDIACVFPHGNGIRS
SDRSEALALQKVWGALDTPVVSYKAQIGYLMASSALVDMALMSGFLGSGSLPAFKCEGEVDAGLGINLHANKSAYRLSGN
AGVKIGLGIEGSVGAAVIRSLRWRRRSP

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 45223; Mature: 45092

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSIAASNVHIAGFGVETGLGFGHARLLQSIENSESAARRGFFGKPFEAGMAGFGFNPQ
CCCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHCCCCCCCCCE
VVSLSAPAKKSNGGYHQALAKDVAGITRKVIVDALDSASIPTDSLTHKRVCVFYGGPGML
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCH
PEIANFLPYIRRNDKNDISFHRGIRNLTFENHNQDAVARLLRDGLGLRERPISVYSASCS
HHHHHHHHHHHCCCCCCHHHHHCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCHH
SFAAAYLAYCSVKSHTCDLAIAVSFQHVSLFDLMFMNGFGGVAAGRSGPFSANGEGTVLG
HHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
DGACAMVLESPAHLHARKGTPYASMDSMVMRQSAGTVSRSTTFTPDFRVIGRTIAKAMED
CCEEEEEECCCHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ANGLGANDIACVFPHGNGIRSSDRSEALALQKVWGALDTPVVSYKAQIGYLMASSALVDM
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ALMSGFLGSGSLPAFKCEGEVDAGLGINLHANKSAYRLSGNAGVKIGLGIEGSVGAAVIR
HHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHH
SLRWRRRSP
HHHHHCCCC
>Mature Secondary Structure 
TSSIAASNVHIAGFGVETGLGFGHARLLQSIENSESAARRGFFGKPFEAGMAGFGFNPQ
CCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHCCCCCCCCCE
VVSLSAPAKKSNGGYHQALAKDVAGITRKVIVDALDSASIPTDSLTHKRVCVFYGGPGML
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCH
PEIANFLPYIRRNDKNDISFHRGIRNLTFENHNQDAVARLLRDGLGLRERPISVYSASCS
HHHHHHHHHHHCCCCCCHHHHHCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCHH
SFAAAYLAYCSVKSHTCDLAIAVSFQHVSLFDLMFMNGFGGVAAGRSGPFSANGEGTVLG
HHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
DGACAMVLESPAHLHARKGTPYASMDSMVMRQSAGTVSRSTTFTPDFRVIGRTIAKAMED
CCEEEEEECCCHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ANGLGANDIACVFPHGNGIRSSDRSEALALQKVWGALDTPVVSYKAQIGYLMASSALVDM
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ALMSGFLGSGSLPAFKCEGEVDAGLGINLHANKSAYRLSGNAGVKIGLGIEGSVGAAVIR
HHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHH
SLRWRRRSP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA