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The map label for this gene is mlaC [H]

Identifier: 121609358

GI number: 121609358

Start: 2718587

End: 2719255

Strand: Direct

Name: mlaC [H]

Synonym: Veis_2401

Alternate gene names: 121609358

Gene position: 2718587-2719255 (Clockwise)

Preceding gene: 121609357

Following gene: 121609359

Centisome position: 48.84

GC content: 64.72

Gene sequence:

>669_bases
ATGAACCGACGTTTCCCGGGGCCTGTGGCTCTTGGCCTGACCCTTTCCTGGGTCTTTTCCTGGGCCCTTTTCTGGGCTCT
TTTCCTGCCATTGCCGGCCCGGGCCGCCGATGAAGCGCCCGATGCGTTGATCCGGCGCCTGTCCACCACGGTGCTCGATG
CGGTAAAGGCCGACCAGGCGATACGCAGCGGTAATCTGGAGCCGCTGATTGCGCTGGTCAACAAGACCGTGATGCCCCAT
GTCAACTTCCGCCGCATGACGGCTGCCGCAGTAGGCCCCGGCTGGCGCCAGGCCACGCCCGGGCAGCAAAAGCGGCTGCA
GGAAGAATTCAAGCTCTTGCTGGTGCGCACCTACGCGGGCGCGCTGGCGCATATCAGTGAGCAGACCATACAGGTCAAGC
CGCTGCGCGCAGCGGCCAGCGACAAAGATGTGCTGGTGCGCACCGAGATCGTTGGCCGGGGCGATCCGATACAGCTGGAC
TACCGCCTGGAAAAAACCCCTGGCGACGGCGCCGGCTGGAAGGTCTACAACCTGAACGTGCTCGGCGTCTGGCTGGTGGA
AACCTACCGGGGCCAGTTCGCGCAGCAGATCAACGCCAAGGGCGTGGACGGTCTGATCGACACGCTGGCCGCGCGCAACA
AGGCCAATGCCGCCGCCAAGGGCGAATGA

Upstream 100 bases:

>100_bases
AGGCCAACGGCATGGATGACGAGGACGCCGACAACCCATCCAGCGAGGGCATGTTGCCCGAAGAGCCTTGAAGGCCAAAA
CCATGAGACCCGTGACCATG

Downstream 100 bases:

>100_bases
TCCCGCGCCATGCTGGCATTGCCCCCCGAACTCACCCAGCGCCAGGCCACGGCCTGCCTGCGCCTGCTGCTGCAAGGGCT
GAAGGCGCAGCCAGAGCGCG

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNRRFPGPVALGLTLSWVFSWALFWALFLPLPARAADEAPDALIRRLSTTVLDAVKADQAIRSGNLEPLIALVNKTVMPH
VNFRRMTAAAVGPGWRQATPGQQKRLQEEFKLLLVRTYAGALAHISEQTIQVKPLRAAASDKDVLVRTEIVGRGDPIQLD
YRLEKTPGDGAGWKVYNLNVLGVWLVETYRGQFAQQINAKGVDGLIDTLAARNKANAAAKGE

Sequences:

>Translated_222_residues
MNRRFPGPVALGLTLSWVFSWALFWALFLPLPARAADEAPDALIRRLSTTVLDAVKADQAIRSGNLEPLIALVNKTVMPH
VNFRRMTAAAVGPGWRQATPGQQKRLQEEFKLLLVRTYAGALAHISEQTIQVKPLRAAASDKDVLVRTEIVGRGDPIQLD
YRLEKTPGDGAGWKVYNLNVLGVWLVETYRGQFAQQINAKGVDGLIDTLAARNKANAAAKGE
>Mature_222_residues
MNRRFPGPVALGLTLSWVFSWALFWALFLPLPARAADEAPDALIRRLSTTVLDAVKADQAIRSGNLEPLIALVNKTVMPH
VNFRRMTAAAVGPGWRQATPGQQKRLQEEFKLLLVRTYAGALAHISEQTIQVKPLRAAASDKDVLVRTEIVGRGDPIQLD
YRLEKTPGDGAGWKVYNLNVLGVWLVETYRGQFAQQINAKGVDGLIDTLAARNKANAAAKGE

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24348; Mature: 24348

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRFPGPVALGLTLSWVFSWALFWALFLPLPARAADEAPDALIRRLSTTVLDAVKADQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRSGNLEPLIALVNKTVMPHVNFRRMTAAAVGPGWRQATPGQQKRLQEEFKLLLVRTYAG
HHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALAHISEQTIQVKPLRAAASDKDVLVRTEIVGRGDPIQLDYRLEKTPGDGAGWKVYNLNV
HHHHHHHCCEEEEECHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEE
LGVWLVETYRGQFAQQINAKGVDGLIDTLAARNKANAAAKGE
EEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNRRFPGPVALGLTLSWVFSWALFWALFLPLPARAADEAPDALIRRLSTTVLDAVKADQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRSGNLEPLIALVNKTVMPHVNFRRMTAAAVGPGWRQATPGQQKRLQEEFKLLLVRTYAG
HHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALAHISEQTIQVKPLRAAASDKDVLVRTEIVGRGDPIQLDYRLEKTPGDGAGWKVYNLNV
HHHHHHHCCEEEEECHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEE
LGVWLVETYRGQFAQQINAKGVDGLIDTLAARNKANAAAKGE
EEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]