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The map label for this gene is fadE20 [H]

Identifier: 121638599

GI number: 121638599

Start: 2989816

End: 2990976

Strand: Reverse

Name: fadE20 [H]

Synonym: BCG_2737c

Alternate gene names: 121638599

Gene position: 2990976-2989816 (Counterclockwise)

Preceding gene: 121638600

Following gene: 121638596

Centisome position: 68.37

GC content: 60.29

Gene sequence:

>1161_bases
ATGGGCAGTGCCACCAAGTACCAGCGCACACTTTTCGAACCCGAACATGAGTTGTTTCGCGAGTCTTACCGGGCGTTCCT
CGATCGCCACGTCGCGCCCTATCACGATGAATGGGAAAAGACCAAGATCGTCGACCGCGGCGTGTGGCTGGAGGCCGGCA
AGCAGGGATTTCTGGGCATGGCGGTGCCCGAGGAGTATGGCGGTGGGGGTAACGCGGACTTCCGGTACAACACGGTCATC
ACCGAGGAAACCTGCGCCGGACGGTACAGCGGGATCGGTTTTGGCCTGCACAACGACATCGTGGCGCCGTACTTGCTGGC
GCTGGCCACCGAAGAGCAGAAGCGGCGCTGGTTTCCCAACTTCTGCACCGGGGAATTGACCACCGCGATCGCGATGACCG
AGCCCGGAACCGGTAGTGACCTGCAAGGTATCACCACCCGTGCCGTCAAACACGGTGATCATTACGTGCTAAACGGGTCA
AAGACGTTCATCACCAACGGGATCAATTCAGACCTAGTGATCGTGGTGGCGCAGACGGATCCCGAAAAGGGTGCGCAAGG
GTTCAGTTTGTTGGTCGTCGAACGCGGCATGGCTGGATTCGAACGCGGCCGCCAGCTGGACAAGATCGGGTTGGACGCCC
AGGACACCGCCGAGCTGTCCTTCACCGACGTGGCGGTTCCAGCCGAAAACCTGCTCGGCCAGGAGGGGATGGGGTTCATC
TACTTGATGCAGAACCTGCCGCAAGAACGGATCTCGATCGCCATCATGGCGGCCGCGGGGATGGAATCCGTGCTGGAGCA
GACACTGCAGTACGCCAAGGAGCGCAAGGCGTTCGGCAGGTCGATCGGTAGCTTCCAGAACAGCCGATTCTTGCTGGCCG
AGCTGGCAACCGAGGCCACTGTGGTGCGCATCATGGTCGACGAATTCATTAAGCTGCACCTGGCGGGGAAGTTGACGGCA
GAGCAGGCCGCCATGGCCAAGTGGTATGCCACCGAGAAGCAGGTGTATCTGAACGACCGCTGTCTGCAGCTGCACGGTGG
GTACGGCTACATGCGCGAATACCCAGTCGCCCGGGCCTATCTCGATTCGCGGGTACAGACGATTTACGGTGGCACGACCG
AGATCATGAAAGAGATCATCGGTCGTGGCTTGGGTGTTTAG

Upstream 100 bases:

>100_bases
GGCGTTACGCTCGCGGCGGCTGGCGCGCCCCGGCTACCTGCCGACCAACCGCCCGGTTGGTATTGTTGGGCACCAGAATT
TTCTTCCCCGGAGGGCATCC

Downstream 100 bases:

>100_bases
GCGCAGCTAGCCCTCAGCTAGCGCGGGCTCACATGTGCGCGTCGCGCGCGGCATGGGCCCTGCACAGCAGCGTCATCAGG
TCGTCGTCCTGTCCGGGCTG

Product: putative acyl-CoA dehydrogenase fadE20

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVI
TEETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGS
KTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFI
YLMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEATVVRIMVDEFIKLHLAGKLTA
EQAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV

Sequences:

>Translated_386_residues
MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVI
TEETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGS
KTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFI
YLMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEATVVRIMVDEFIKLHLAGKLTA
EQAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
>Mature_385_residues
GSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVIT
EETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGSK
TFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIY
LMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEATVVRIMVDEFIKLHLAGKLTAE
QAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=50.531914893617, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=33.9572192513369, Blast_Score=228, Evalue=8e-60,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=35.1190476190476, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=33.9622641509434, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=32.0954907161804, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI4501859, Length=372, Percent_Identity=32.7956989247312, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=30.6493506493506, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=30.6493506493506, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=30.3191489361702, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=30.3191489361702, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI21361497, Length=339, Percent_Identity=32.7433628318584, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4503943, Length=371, Percent_Identity=27.7628032345013, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=27.247191011236, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38505218, Length=358, Percent_Identity=25.1396648044693, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI48976061, Length=408, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI211971008, Length=408, Percent_Identity=25, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87081958, Length=378, Percent_Identity=29.8941798941799, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=25.6, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081702, Length=359, Percent_Identity=24.7910863509749, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082384, Length=264, Percent_Identity=26.1363636363636, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=368, Percent_Identity=33.9673913043478, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=390, Percent_Identity=34.1025641025641, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=30.4709141274238, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=30.5630026809651, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=32.2666666666667, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=338, Percent_Identity=31.9526627218935, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=384, Percent_Identity=29.1666666666667, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=346, Percent_Identity=30.9248554913295, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=29.4429708222812, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=33.7837837837838, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=32.8690807799443, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=31.8777292576419, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=278, Percent_Identity=34.1726618705036, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=30.1818181818182, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=27.9683377308707, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=29.7071129707113, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=28.0276816608997, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=32.9815303430079, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI21356377, Length=366, Percent_Identity=32.5136612021858, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=30.8510638297872, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=30.5630026809651, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI281363737, Length=369, Percent_Identity=32.7913279132791, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=31.1827956989247, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=27.8215223097113, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42833; Mature: 42702

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRGVWLEAGKQGFLGM
CCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEECCCCCCEEE
AVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPN
ECCHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCC
FCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCEEEECCCCCCEEEEEEECC
PEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFI
CCCCCCCEEEEEEECCCHHHHHCCCHHHCCCCCCCCCCEEEEEEECCHHHHCCCCCCCEE
YLMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEAT
EHHHHCCHHHHEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VVRIMVDEFIKLHLAGKLTAEQAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCEEEEEECCCCHHHHCHHHHHH
LDSRVQTIYGGTTEIMKEIIGRGLGV
HHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRGVWLEAGKQGFLGM
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEECCCCCCEEE
AVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPN
ECCHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCC
FCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCEEEECCCCCCEEEEEEECC
PEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFI
CCCCCCCEEEEEEECCCHHHHHCCCHHHCCCCCCCCCCEEEEEEECCHHHHCCCCCCCEE
YLMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEAT
EHHHHCCHHHHEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VVRIMVDEFIKLHLAGKLTAEQAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCEEEEEECCCCHHHHCHHHHHH
LDSRVQTIYGGTTEIMKEIIGRGLGV
HHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]