| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is mbtF [H]
Identifier: 121638258
GI number: 121638258
Start: 2622722
End: 2627107
Strand: Reverse
Name: mbtF [H]
Synonym: BCG_2393c
Alternate gene names: 121638258
Gene position: 2627107-2622722 (Counterclockwise)
Preceding gene: 121638259
Following gene: 121638257
Centisome position: 60.05
GC content: 67.74
Gene sequence:
>4386_bases ATGGGACCAGTGGCCGTGACGCGAGCCGACGCGCGGGGCGCCATCGACGATGTGATGGCGCTCAGCCCATTGCAACAGGG ACTGTTTTCTAGGGCGACACTGGTCGCCGCGGAGTCCGGCTCTGAGGCCGCAGAGGCCGACCCGTATGTGATCGCGATGG CGGCCGACGCGGCCGGCCCGCTCGACATCGCCTTGCTTCGCGACTGCGCTGCCGCGATGCTGACCCGGCACCCCAACCTG CGGGCGAGCTTCCTACACGGGAACCTGAGCCGGCCCGTGCAGGTAATACCATCCAGTGCCGAGGTGCTTTGGCGTCACGT GCGCGCCCACCCCAGTGAGGTCGGGGCGCTGGCAGCCGAAGAGCGCCGGCGCCGCTTCGACGTCGGCCGCGGACCACTCA TCCGGTTCCTGCTCATCGAACTACCGGACGAATGTTGGCATCTGGTCATCGTCGCGCACCACATCGTCATCGACGGATGG TCGTTGCCGCTGTTCGTCTCCGAGCTGCTCGCCTTGTATCGGGCTGGTGGTCACGTCGCCGCGTTGCCGGCAGCGCCGCG GCCGTATCGCGACTACATCGGCTGGCTGGCCGGCCGCGATCAGACGGCTAGCCGCGCAATGTGGGCGGACCACCTCAATG GCCTGGACGGCCCGACTCTGTTATCGCCGGCACTCGCCGACACTCCTGTGCAGCCGGGTATTCCGGGACGCACCGAAGTG CGCCTTGACCGTGAAGCCACCGCGGAGCTGGCCGATGCCGCCCGCACCCGTGGCGTCACGATCAGCACACTTGTTCAAAT GGCTTGGGCTACCACGCTTTCAGCATTCACCGGTCGTGGCGATGTGACGTTCGGTGTGACGGTGTCCGGCAGGCCCAGCG AACTGTCCGGCGTGGAAACGATGATCGGCCTGTTCATCAATACGGTGCCACTGCGGGTCCGCCTGGACGCCCGCGCTACC GTCGGCGGGCAATGCGCTGTCCTACAACGTCAATTCGCCATGTTGCGCGACCACAGCTATCTCGGTTTCAACGAGTTTCG TGCCATCGCCGGTATCGGTGAGATGTTCGACACCCTACTGGTGTATGAGAACTTCCCGCCCGGCGAGGTGGTGGGCACCG CGGAGTTCGTCGCAAACGGGGTGACGTTCCGTCCGGTGGCGCTAGAGAGTTTGTCGCACTTTCCGGTGACCGTCGCCGCG CACCGCAGCACCGGTGAGCTCACGCTGCTAGTGGAGGTGCTCGACGGTGCGCTGGGCACGATGGCGCCCGAAAGCCTCGG CAGGCGGGTGCTGGCTGTGTTACAGCGCTTGGTCAGCCGGTGGGATCGGCCGCTGCGCGACGTCGACATTCTGCTGGACG GCGAGCACGATCCGACCGCACCCGGCCTGCCGGATGTGACGACGTCGGCACCCGCGGTGCATACCCGGTTCGCCGAAATC GCTGCGGCACAGCCTGACTCGGTGGCGGTCAGTTGGGCGGATGGTCAGCTGACGTACCGGGAGCTGGATGCATTGGCCGA CCGGCTGGCCACTGGGCTGCGCCGCGCGGACGTGAGTCGCGAGACCCCGGTGGCCGTCGCGCTGTCCCGTGGTCCGCGCT ACGTGGCCGCCATGCTGGCGGTCCTCAAGGCGGGTGGCATGATCGTGCCGCTGGACCCGGCGATGCCCGGTGAGCGTGTC GCCGAGATCTTGCGCCAGACATCGGCTCCGGTGGTCATCGATGAGGGCGTGTTCGCCGCTTCGGTTGGCGCTGACATACT CGAGGACGACCGTGCCATCACGGTGCCGGTGGACCAGGCGGCCTACGTGATTTTCACCTCCGGCACCACCGGTACCCCGA AAGGTGTCATCGGCACCCATCGGGCGCTGTCGGCCTACGCCGACGACCACATCGAGCGCGTGTTGCGGCCGGCGGCCCAG CGGCTCGGGCGCCCGCTGCGAATCGCGCATGCCTGGTCGTTCACCTTCGACGCGGCGTGGCAGCCGTTGGTCGCACTGCT TGACGGCCACGCGGTGCACATTGTCGACGACCATCGTCAGCGGGACGCAGGGGCGCTGGTCGAAGCGATCGACCGATTCG GTCTGGACATGATTGACACCACGCCGTCGATGTTCGCCCAGCTGCACAACGCTGGACTGCTCGACCGGGCGCCGTTGGCG GTGCTTGCGCTCGGCGGCGAAGCCTTGGGCGCCGCGACGTGGCGGATGATCCAGCAGAACTGCGCGCGCACGGCCATGAC GGCCTTCAACTGCTACGGGCCTACCGAGACCACGGTCGAAGCCGTGGTCGCCGCCGTTGCTGAGCATGCGCGACCGGTCA TCGGACGTCCGACCTGCACCACCCGCGCCTACGTCATGGACTCCTGGCTGCGGCCGGTGCCCGATGGCGTCGCCGGCGAG CTGTATCTGGCGGGCGCCCAGTTGACCCGCGGTTACCTCGGCCGCCCGGCCGAGACTGCGGCGCGCTTTGTCGCTGAGCC AAACGGGCGCGGTAGCCGAATGTACCGCACCGGAGATGTGGTGCGCCGCCTGCCCGACGGTGGGCTGGAGTTCCTCGGGC GCAGCGATGACCAGGTGAAGATCCGCGGTTTCCGCGTCGAGCCGGGTGAGATTGCCGCGGTGCTCAACGGCCACCATGCG GTGCACGGTTGCCATGTGACGGCCCGCGGCCATGCCAGTGGCCCCCGGCTGACGGCGTATGTGGCAGGCGGACCACAACC GCCACCGGTGGCCGAATTGCGGGCGATGCTGCTAGAGCGGTTGCCGCGTTATCTAGTCCCGCACCATATCGTCGTCCTCG ACGAGTTACCGCTGACTCCACACGGCAAGATCGACGAAAACGCTTTGGCGGCAATCAATGTCACCGAAGGACCGGCAACT CCGCCGCAGACACCGACCGAGCTGGTGCTGGCCGAGGCGTTCGCCGATGTCATGGAAACCTCGAACGTCGATGTCACCGC GGGCTTTTTGCAGATGGGTCTAGACAGCATCGTGGCGCTGTCGGTGGTGCAGGCCGCGCGCCGTCGTGGGATTGCGTTGC GGGCCAGGCTGATGGTGGAGTGCGACACCATCCGTGAACTCGCGGCGGCCATTGACTCCGATGCCGCATGGCAGGCACCG GCCAACGATGCCGGCGAGCCGATCCCGGTGCTACCCAACACTCATTGGCTCTACGAGTACGGCGACCCGCGCCGGCTGGC ACAAACCGAGGTCATCAGGTTGCCCGACCGGATCACCCGCGAACGCCTGGATGCCGTGTTGGCCGCGGTCGTCGACGGAC ACGAGGTGTTGCGGTGCCGGTTCGACCGGGATGCGATGGCCCTTGTCGCACAACCGAAAACGGACATTCTCAGCGAGGTT TGGGTCAGCGGTGAACTGGTCACCGCGGTGGCCGAGCAGACTCTTGGCGTGCTGGCGAGTCTCGACCCCCAGGCCGGCCG ACTGCTCTCGGCGGTGTGGCTGCGCGAACCCGACGGGCCCGGTGTTCTGGTGCTGACCGCCCATGTGCTGGCGATGGACC CAGCCTCCTGGCGGATTGTGCTGGGTGAACTCGACGCCGGCCTGCACGCGCTGGCGGCCGGGCGCGCGCCCAGCCCAGCG CGCGAGAACACCAGCTACCGGCAGTGGTCGCGGCTGCTGGCGCAGCGGGCTAAGGCGCTGGATAGCGTTGATTTCTGGGT CGCCGAACTCGAGGGCGCCGATCCGCCGTTGGGTGCCCGCAGGGTGGCGCCGCAGACCGACCGGGTTGGTGAGCTAGCGA TCACCATGTCGATCTCCGACGCCGATCTGACCGCGCGGCTGCTTTCGACGGGACGGTCGATGACCGATCTGCTGGCTACC GCCGCTGCGCGGATGGTGACCGCCTGGCGCCGGCAACGCGGTCAACAAACACCAGCACCGCTGTTGGCGTTGGAGACGCA TGGCCGCGCGGACGTCCACGTCGATAAGACTGCCGACACCAGCGACACGGTCGGGCTGCTCAGCGCGATCTATCCGCTGC GCATCCACTGCGACGGCGCGACCGACTTCGCGCGGATACCCGGCAGCGGCATCGATTACGGCCTGCTGCGGTACCTGCGC GCCGATACCGCGGAGCGACTACGCGCCCACCGCGAACCCCAGCTGCTGCTGAACTATCTGGGTAGCCTGCACGTCGGGGT GGGAGATCTGGCGGTCGACCGCGCACTACTGGCTGATGTGGGGCAACTGCCTGAACCCGAACAGCCGGTGCGCCACGAAC TGACGGTGCTGGCGGCGCTCCTCGGGCCCGCCGACGCTCCCGTGCTAGCCACGCGGTGGCGCACGCTGCCCGACATCCTG TCCGCCGACGACGTCGCCACGCTGCAATCACTGTGGCAGGGCGCGCTGGCGGAGATAACAGCATGA
Upstream 100 bases:
>100_bases ACGCCAAGCCTCACGTCGAGGCCGAGCCGGACGACAAGCATCACGCGCCGATGAGCACATCAGGGCTTTCCCCAGACGAA CTGTCGGCCCTGACCGCGTC
Downstream 100 bases:
>100_bases ATCCGACGCTCGCGGTCCTGGGCGCTGGAGCCAAGGCGGTGGCGGTCGCGGCCAAGGCATCCGTGCTGCGTGACATGGGG GTCGACGTGCCCGACGTGAT
Product: peptide synthetase mbtF
Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]
Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]
Number of amino acids: Translated: 1461; Mature: 1460
Protein sequence:
>1461_residues MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNL RASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGW SLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEV RLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRVRLDARAT VGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAA HRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEI AAAQPDSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERV AEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQ RLGRPLRIAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLA VLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDGVAGE LYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHA VHGCHVTARGHASGPRLTAYVAGGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPAT PPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAP ANDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEV WVSGELVTAVAEQTLGVLASLDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPA RENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGRSMTDLLAT AAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLR ADTAERLRAHREPQLLLNYLGSLHVGVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDIL SADDVATLQSLWQGALAEITA
Sequences:
>Translated_1461_residues MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNL RASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGW SLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEV RLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRVRLDARAT VGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAA HRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEI AAAQPDSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERV AEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQ RLGRPLRIAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLA VLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDGVAGE LYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHA VHGCHVTARGHASGPRLTAYVAGGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPAT PPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAP ANDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEV WVSGELVTAVAEQTLGVLASLDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPA RENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGRSMTDLLAT AAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLR ADTAERLRAHREPQLLLNYLGSLHVGVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDIL SADDVATLQSLWQGALAEITA >Mature_1460_residues GPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNLR ASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGWS LPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVR LDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLFINTVPLRVRLDARATV GGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAAH RSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIA AAQPDSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERVA EILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQR LGRPLRIAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLAV LALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDGVAGEL YLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAV HGCHVTARGHASGPRLTAYVAGGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPATP PQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPA NDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEVW VSGELVTAVAEQTLGVLASLDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPAR ENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGRSMTDLLATA AARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLRA DTAERLRAHREPQLLLNYLGSLHVGVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDILS ADDVATLQSLWQGALAEITA
Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes
COG id: COG1020
COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 4 acyl carrier domains [H]
Homologues:
Organism=Escherichia coli, GI1786801, Length=1078, Percent_Identity=28.0148423005566, Blast_Score=236, Evalue=6e-63, Organism=Escherichia coli, GI145693145, Length=517, Percent_Identity=25.531914893617, Blast_Score=105, Evalue=2e-23, Organism=Escherichia coli, GI1786810, Length=507, Percent_Identity=25.4437869822485, Blast_Score=97, Evalue=9e-21, Organism=Escherichia coli, GI1788107, Length=368, Percent_Identity=28.5326086956522, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17556356, Length=1167, Percent_Identity=21.5938303341902, Blast_Score=106, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994690, Length=371, Percent_Identity=23.1805929919137, Blast_Score=70, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994694, Length=371, Percent_Identity=23.1805929919137, Blast_Score=70, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994703, Length=371, Percent_Identity=23.1805929919137, Blast_Score=69, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6319591, Length=705, Percent_Identity=24.2553191489362, Blast_Score=135, Evalue=7e-32, Organism=Drosophila melanogaster, GI24648676, Length=608, Percent_Identity=25.1644736842105, Blast_Score=139, Evalue=1e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR010071 - InterPro: IPR009081 - InterPro: IPR020845 - InterPro: IPR000873 - InterPro: IPR001242 - InterPro: IPR013120 - InterPro: IPR016040 - InterPro: IPR010060 - InterPro: IPR006163 - InterPro: IPR020806 - InterPro: IPR006162 - InterPro: IPR010080 [H]
Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]
EC number: 2.7.7.- [C]
Molecular weight: Translated: 156764; Mature: 156633
Theoretical pI: Translated: 5.69; Mature: 5.69
Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGP CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEECCCCCC LDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAE HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHH ERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVA HHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEE ALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEV ECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCEE RLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVET EECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH MIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLL HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH VYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGT HCCCCCCCCEEECHHHHHCCCEECHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHC MAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEI CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH AAAQPDSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLA HCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH VLKAGGMIVPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQA HHHCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEHHHCCHHHCCCCEEEEECCCC AYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAW EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHH QPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLA HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCEE VLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCT EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC TRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDV HHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEHHHH VRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAY HHHCCCCCHHHCCCCCCEEEEEEEEECCHHEEEEECCCEEEEEEEEEECCCCCCCEEEEE VAGGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPAT ECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC PPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVE CCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH CDTIRELAAAIDSDAAWQAPANDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITR HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHH ERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEVWVSGELVTAVAEQTLGVLAS HHHHHHHHHHHCCCHHEEEECCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHC LDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPA CCCHHHHHHHHHHEECCCCCCEEEEEEHHHHCCCCCEEEEEEECCCCHHHHHCCCCCCCC RENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISD CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECC ADLTARLLSTGRSMTDLLATAAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADT HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCC SDTVGLLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYL CHHHHHHHHHCEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH GSLHVGVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDIL HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH SADDVATLQSLWQGALAEITA CCCHHHHHHHHHHHHHHHCCC >Mature Secondary Structure GPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGP CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEECCCCCC LDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAE HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHH ERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVA HHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEE ALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEV ECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCEE RLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVET EECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH MIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLL HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH VYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGT HCCCCCCCCEEECHHHHHCCCEECHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHC MAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEI CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH AAAQPDSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLA HCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH VLKAGGMIVPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQA HHHCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEHHHCCHHHCCCCEEEEECCCC AYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAW EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHH QPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLA HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCEE VLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCT EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC TRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDV HHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEHHHH VRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAY HHHCCCCCHHHCCCCCCEEEEEEEEECCHHEEEEECCCEEEEEEEEEECCCCCCCEEEEE VAGGPQPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPAT ECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC PPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVE CCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH CDTIRELAAAIDSDAAWQAPANDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITR HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHH ERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEVWVSGELVTAVAEQTLGVLAS HHHHHHHHHHHCCCHHEEEECCCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHC LDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPA CCCHHHHHHHHHHEECCCCCCEEEEEEHHHHCCCCCEEEEEEECCCCHHHHHCCCCCCCC RENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISD CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECC ADLTARLLSTGRSMTDLLATAAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADT HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCC SDTVGLLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYL CHHHHHHHHHCEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH GSLHVGVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDIL HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH SADDVATLQSLWQGALAEITA CCCHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: Phosphopantetheine. [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]
Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser
General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA