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The map label for this gene is mbtE [H]

Identifier: 121638259

GI number: 121638259

Start: 2627089

End: 2632137

Strand: Reverse

Name: mbtE [H]

Synonym: BCG_2394c

Alternate gene names: 121638259

Gene position: 2632137-2627089 (Counterclockwise)

Preceding gene: 121638260

Following gene: 121638258

Centisome position: 60.17

GC content: 66.33

Gene sequence:

>5049_bases
ATGTGGTTCGTGCAGATGGCCGACCCCAGCGGTGCGTTACTCAACATCTGTGTGTCCTACCGCATCACCGGTGACATCGA
TCTGGCCAGGTTGCGCGACGCAGTCAACGCCGTCGCCCGTCGCCATCGGATACTGCGTACCACCTACCCTGTCGGCGACG
ACGGAGTCGCCCAGCCGACCGTGCACGCGGATCTTCGCCCCGGCTGGACACAATACGACCTGACGGACCTGTCCCAACGC
GCCCAGCGGCTGCGCCTGGAGGTGTTGGCTCAGCGCGAATTCTGCGCTCCCTTCGAGCTTTCCCGCGACGCGCCATTGCG
AATCACGGTGGTGCGCACGGCTGCCGACGAACACGTGCTGCTGTTGGTGGCCCACCACATCGCCTGGGATGATGGTTCGT
GGCGGGTGTTCTTCACCGATCTCACCCAGGCGTACTCGCGAGCTGACCTAGGGGCCGATCTGGGGCCAGAACACCGTCCG
TCGGCCGCATCCGGACCCGACACTACCGAGGCCGACCTCAACTATTGGCGCGCGATCATGGCCGATCCGCCAGAGCCGCT
GGAACTTCCCGGCCCAGCCGGAACGTGTGTGCCGACCAGTTGGCGTGCCGCGCGCGCCACGTTGCGGCTGCCCGCCGACA
CCGCTGCGCGGGTGGCCACGATGGCGAAGAACACCGGTTGCACTCCCTACATGGTGCTGCTGGCCGCGTTCGGTGCCCTG
GTGCATCGCTACACCCACAGTGACGACTTCCTCGTGGCGGCTCCGGTGCTCAACCGTGGCGCCGGAACCGAAGATGCCAT
CGGCTATTTCGGCAACACGGTAGCGATGCGGCTGCGACCGCAATCGGCGATGAGTTTCCGGGAGTTGCTGACCGCCACCC
GCGACATCGCCAGCGGGGCGTTCGCACACCAACGGATCAACCTCGACCGCGTGGTAAGGGAACTGAACCCCGATCGCCGG
CACGGTGCCGAGCGCATGACCCGGGTCAGCTTCGGTTTCCGGGAGCCCGACGGCGGCGGATTCAACCCGCCAGGCATCGA
GTGCGAGCGCTACGACCTGCGCAGCAACATCACGCAGCTGCCGTTGGGCTTCATGGTCGAATTCGACCGCGCGGGTGTGC
TGGTCGAGGCCGAACACCTGGTGGAGATCCTGGAACCCGCCCTGGCCAAGCAGATGCTTCGACACTTCGGTGTGCTGCTC
GACAATGCGCTGGCCGCCCCCGACAACACGTTGTCGGGGCTGGCGCTGATGGATGAGCGCGACGCCGCCAGGCTGCGCGA
GGTGTCGCGCGGCGAGCGGTTCGATACCCCTGTCAAAACCCTCGTGGACCTGGTGAACGAGCAGACCACGCGGACTCCCG
ACGCCACCGCCGTGGTGTATGAGGGCCAACACTTCACCTACCACGACCTCAATGAGGCGTCGAACCGGTTGGGGCACTGG
CTGATCGAGCAGGGGATAGGCAGCGAAGACCGGGTCGCGGTACTTCTTGACAAATCGCCGGACCTGATCGTCACGGCCTT
GGGGGTGGTCAAGTCCGGGGCGGTGTATGTGCCCGTGGATCCCAGCTACCCGCAAGACCGGCTGGATTTCATCCTCGCCG
ACTGCGACGCGAAACTGGTGCTGCGCACGCCAGTACGTGAGCTGGCCGGATACCGCAGCGACGACCCCACCGACGCCGAT
CGAATCCGGCCGCTACGGCCAGACAACACGGCCTATCTCATCTACACGTCCGGTACCACCGGATTGCCCAAAGGTGTCGC
GGTGCCACACCGCCCCGTCGCCGAGTACTTCGTCTGGTTCAAGGGCGAATACGACGTCGACGACACCGACCGGCTACTGC
AGGTCGCCTCACCCAGCTTCGACGTCTCGATCGCCGAGATCTTCGGCACGCTGGCCTGTGGCGCGCGGATGGTGATACCA
CGCCCCGGGGGACTCACCGACATTGGATATCTCACCGCCCTGTTGCGCGACGAGGGCATCACGGCAATGCATTTCGTGCC
GTCCCTACTCGGGCTGTTCCTGTCGCTGCCGGGTGTGAGCCAGTGGCGGACGTTGCAGCGGGTACCCATCGGCGGGGAGC
CGCTACCCGGTGAGGTGGCCGACAAGTTCCACGCGACATTCGATGCGCTGCTGCACAACTTCTACGGTCCAACCGAAACC
GTGATCAACGCCAGCCGGTTTAAAGTGGTGGGCCCACAGGGCACCCGCATCGTGCCCATCGGCCGGCCCAAGATCAACAC
CACCATGCACCTGCTCGACGATTCGTTGCAGCCGGTGCCGACCGGTGTGATCGGCGAGATCTATATTGGAGGGACGCATG
TCGCATACGGATACCATCGCCGCGCCGGGCTGACCGCGGAGCGATTCGTTGCCGACCCGTTTAATCCCGGTTCCCGCATG
TACCGGTCCGGGGATCTGGCGCGCCGCAATGCTGACGGTGACATCGAGTTCGTGGGCCGTGCCGACGAGCAGGTCAAGAT
TCGCGGATTCCGAATCGAACTCGGTGACGTAGCAGCGGCCATCGCGGTCGACCCTACGGTCGGGCAGGCCGTTGTGGTGG
TTAGCGACCTGCCGCGGCTGGGCAAGAGTCTGGTGGGCTACGTGACACCCGCCGCGGGCGGCGACGGACCCGCCGATGTC
GGCGTCGATCTCGACCGCATCCGCGCCCGGGTGGCCGCGGCACTGCCTGAATATATGCTGCCCGCGGCCTATGTTGTGCT
GGATGAGATTCCGATCACCGCGCATGGCAAAATCGACCGCGCCGCGCTGCCGGAACCGCAGATCGCGTCGGACACCGAGT
TCCGCGCGCCGCAGACCGCCACCGAGCGGCGCCTTGCCCAACTGTTCGGTGAGCTGCTCGGCCGCGACCGAGTGGGTGCT
GACGACTCGTTCTTCGACCTCGGCGGTCACTCGCTGCTGGCAACCAAACTCGTTGCGGCCGTGCGCAACGCGTTCGGCGT
CGATGTCGGTGTGCGGGAGATCTTCGAATTCGCCACGGTGACCGCGTTGGCCGGACACATCGATACGTTGGATTCGGATT
CGGCGAGGCCGCGGCTGACCCGGGTGGATCATGACGGGCCAGTGCGATTGTCGTCGTCTCAAATGCGTAGCTGGTTCAAC
TATCGCTTCGACGGGCCCAACGCCGTCAACAACATTCCCTTCGCCGCGGCATTGCATGGGCCCTGCGACACCAACGCGTT
CGCGGCGGCCATCACCGATGTGGTGGCACGCCACGAGATCCTGCGCACCGTCTACCGCGAGATCGGCGGCGTGCCACACC
AGATCATCCAGCCGCCCGCCGAGGTGCCGGTGCGGTGCGCCGCCGGGTCCGACGCCGCGTGGCTGCGAGCCGAACTGAAC
AACGAGCGAGGTTACGTTTTCGACCTGGAAACCGACTGGCCGATCCGGGCGGCGCTGCTGAGCACGCCGGAGCAGACCGT
GTTGTCGCTGGTGGTGCATCACATCGCCGGCGACCACTGGTCGGCTGGGGTGTTGTTCACCGATCTGCTGACCGCATACC
GGGCCCGCAGCACCGGACAACGGCCGTCGTGGGCACCGCTGCCGGTGCAGTACGCCGACTACAGCGTGTGGCAGTCGGCG
CTACTCGACGACGGTGCGGGCATCGTCGGTCCGCAACGCGACTACTGGATCCGCCAGCTGGGGGGCCTGGCAGGCGAAAC
CGGTCTGCGCCCGGACTTCCCGCGCCCGGCCCTGCTCAGCGGTGCCGGTGACGCGGTCGAATTTCGTCTCGGCGCCGCGA
TCCGCGACAAATTGGCTGCCGTGAGCCGAGACCTCGGTGTCACCGAGTTCATGCTGCTACAGGCCGCCGTCGCGGTGGTG
TTACACAAGGCCGGCGGCGGGGTAGACGTCCCCATCGGCGCCCCGGTGGCCGGTCGCAGCGAGGCCAACCTGGACCAGCT
CATCGGGTTCTTCATCAACATCGTGGTGTTGCGCAACGACCTGCGCGGGAACCCCACGCTGCGCGAGGTGCTGCAGCGCA
CCAGGCAGATGGCGCTGGCAGCGTATGCACATCAGGACCTGCCGTTCGACCAGGTGGTGGAGGCGGTCAACCCCCAGCGG
TCGCTGTCCCGCAATCCGTTGTTCGACATTGTTGTGCACGTTCGCGAACAAATGCCGCAAGACCACGTCATCGACACCGG
GCCCGACGGTGACACCACGTTGCGCGTGCTGGAGCCGACATTCGATGCCGCGCAAGCCGATCTATCGGTCAACTTCTTCG
CCTGCGGCGACGAGTACCGCGGCCACGTCATCTACCGCACCGAGTTGTATGAGCGCGCCACCGCACAACGCTTCGCCGAC
TGGCTAGTCCGTGTCGTCGAGGCGTTCGCCGACCGTCCGGACCAACCGCTGCGCGAGGTCGAGATGGTCAGCGCGCAAGC
CAGACGGCGCATTTTGGACCGGTCCAATGCGGGCGCCGGAACGGCCCGGGTGTACCTGCTTGACGACGCACTTAAGCCCG
TTCCGGTAGGCGTGGTGGGTGACGTTTATTACGGTGGCGGTCCCGCCGTCGGTGCCCGGTTGGCCCGGCCATCGGAGACC
GCGACCCGATTCGTTGCCGATCCGTTCGCCGCGCAACCGGGTTCTCGGCTCTACCGCAACGGCGAGCGCGGAGTGTGGAA
GGCCGACGGCCAACTGGAGCTGCTGGCCGAAATCGAACGGCTGCCAACGGCGCAGGCGGCACCGGTGCCGGCCGAGCCCG
CCGACACCGAAACCGAGCGCGCGCTGGCTGCCATCCTCGCCGACGTGCTCGAGGTGGGGGAGGTCGGACGCTACGACGAC
TTCTTCAACCTCGGCGGCGACAGCATCCTCGCGACTCAGGTGGCTGCCCGGGCTCGAGATGGCGGGATACCGCTGACCGC
GCGGATGGTTTTCGAGCATCCCGTTTTGTGTGAGCTCGCCGCCGCGGTCGACGCCAAGCCTCACGTCGAGGCCGAGCCGG
ACGACAAGCATCACGCGCCGATGAGCACATCAGGGCTTTCCCCAGACGAACTGTCGGCCCTGACCGCGTCATGGGACCAG
TGGCCGTGA

Upstream 100 bases:

>100_bases
GGAGCTGCTGCGTCGCAGGCTCGCCGACCGCGGCCTGTCCTCGGCTGCGCAGGACATTGGCCCGCACACTGACGATCGGC
TCTCCGACGGCCAGGCCCGG

Downstream 100 bases:

>100_bases
CGCGAGCCGACGCGCGGGGCGCCATCGACGATGTGATGGCGCTCAGCCCATTGCAACAGGGACTGTTTTCTAGGGCGACA
CTGGTCGCCGCGGAGTCCGG

Product: peptide synthetase mbtE

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1682; Mature: 1682

Protein sequence:

>1682_residues
MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQR
AQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRP
SAASGPDTTEADLNYWRAIMADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGAL
VHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRR
HGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLL
DNALAAPDNTLSGLALMDERDAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHW
LIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDAD
RIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIP
RPGGLTDIGYLTALLRDEGITAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTET
VINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRM
YRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADV
GVDLDRIRARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGA
DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFN
YRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELN
NERGYVFDLETDWPIRAALLSTPEQTVLSLVVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
LLDDGAGIVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVV
LHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQR
SLSRNPLFDIVVHVREQMPQDHVIDTGPDGDTTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFAD
WLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSET
ATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDD
FFNLGGDSILATQVAARARDGGIPLTARMVFEHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQ
WP

Sequences:

>Translated_1682_residues
MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQR
AQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRP
SAASGPDTTEADLNYWRAIMADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGAL
VHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRR
HGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLL
DNALAAPDNTLSGLALMDERDAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHW
LIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDAD
RIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIP
RPGGLTDIGYLTALLRDEGITAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTET
VINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRM
YRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADV
GVDLDRIRARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGA
DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFN
YRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELN
NERGYVFDLETDWPIRAALLSTPEQTVLSLVVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
LLDDGAGIVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVV
LHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQR
SLSRNPLFDIVVHVREQMPQDHVIDTGPDGDTTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFAD
WLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSET
ATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDD
FFNLGGDSILATQVAARARDGGIPLTARMVFEHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQ
WP
>Mature_1682_residues
MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQR
AQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRP
SAASGPDTTEADLNYWRAIMADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGAL
VHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRR
HGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLL
DNALAAPDNTLSGLALMDERDAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHW
LIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDAD
RIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIP
RPGGLTDIGYLTALLRDEGITAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTET
VINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRM
YRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADV
GVDLDRIRARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGA
DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFN
YRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELN
NERGYVFDLETDWPIRAALLSTPEQTVLSLVVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
LLDDGAGIVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVV
LHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQR
SLSRNPLFDIVVHVREQMPQDHVIDTGPDGDTTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFAD
WLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSET
ATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDD
FFNLGGDSILATQVAARARDGGIPLTARMVFEHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQ
WP

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=462, Percent_Identity=25.7575757575758, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI122937307, Length=507, Percent_Identity=21.8934911242604, Blast_Score=79, Evalue=3e-14,
Organism=Escherichia coli, GI1786801, Length=813, Percent_Identity=32.1033210332103, Blast_Score=352, Evalue=8e-98,
Organism=Escherichia coli, GI145693145, Length=526, Percent_Identity=26.8060836501901, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1786810, Length=552, Percent_Identity=23.0072463768116, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788107, Length=549, Percent_Identity=23.1329690346084, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI221142682, Length=434, Percent_Identity=24.8847926267281, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17556356, Length=941, Percent_Identity=24.0170031880978, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17550940, Length=970, Percent_Identity=21.6494845360825, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17560308, Length=560, Percent_Identity=22.8571428571429, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32564422, Length=501, Percent_Identity=23.5528942115768, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32564420, Length=501, Percent_Identity=23.5528942115768, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994690, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=558, Percent_Identity=20.9677419354839, Blast_Score=82, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=901, Percent_Identity=25.9711431742508, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24648676, Length=648, Percent_Identity=29.6296296296296, Blast_Score=224, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24581924, Length=398, Percent_Identity=25.8793969849246, Blast_Score=83, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 183284; Mature: 183284

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPT
CEEEEECCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC
VHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEE
LLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIM
EEEEEHHEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGAL
CCCCCCCCCCCCCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGA
HHHHCCCCCEEEECCHHCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCH
FAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQL
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHCCHHHC
PLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDER
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCH
DAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHW
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHH
LIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLV
HHHHCCCCCCCEEEEEECCCCEEEHHHHHHHCCCEEEECCCCCCHHHHHEEEECCCCEEE
LRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWF
EECCHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHEEEEE
KGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGI
CCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
TAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTET
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
VINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHR
HCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEECHHH
RAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAA
HCCCCHHHHCCCCCCCCHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEEEEECCCEEEE
IAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYML
EEECCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PAAYVVLDEIPITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLT
CCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
RVDHDGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEI
ECCCCCCEEECHHHHHHHHCEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALL
HHHHHHHHCCCCHHHHCCCHHCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHH
STPEQTVLSLVVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LLDDGAGIVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAA
HHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHHH
VSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRND
HHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCC
DHVIDTGPDGDTTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFAD
CCCCCCCCCCCCEEEEECCCCCCHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHH
WLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEE
DVYYGGGPAVGARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIER
CCEECCCHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHH
LPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCC
GGIPLTARMVFEHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQ
CCCCEEEHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
WP
CC
>Mature Secondary Structure
MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPT
CEEEEECCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC
VHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEE
LLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIM
EEEEEHHEECCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGAL
CCCCCCCCCCCCCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGA
HHHHCCCCCEEEECCHHCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCH
FAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQL
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHCCHHHC
PLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDER
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCH
DAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHW
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHH
LIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLV
HHHHCCCCCCCEEEEEECCCCEEEHHHHHHHCCCEEEECCCCCCHHHHHEEEECCCCEEE
LRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWF
EECCHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHEEEEE
KGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGI
CCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
TAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTET
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
VINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHR
HCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEECHHH
RAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAA
HCCCCHHHHCCCCCCCCHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEEEEECCCEEEE
IAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYML
EEECCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PAAYVVLDEIPITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLT
CCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
RVDHDGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEI
ECCCCCCEEECHHHHHHHHCEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LRTVYREIGGVPHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALL
HHHHHHHHCCCCHHHHCCCHHCCEEEECCCCCEEEEEEECCCCCEEEEECCCCCHHHHHH
STPEQTVLSLVVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
LLDDGAGIVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAA
HHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHHH
VSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRND
HHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCC
DHVIDTGPDGDTTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFAD
CCCCCCCCCCCCEEEEECCCCCCHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHH
WLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEE
DVYYGGGPAVGARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIER
CCEECCCHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHH
LPTAQAAPVPAEPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCC
GGIPLTARMVFEHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQ
CCCCEEEHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
WP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]