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The map label for this gene is ychM [H]

Identifier: 120610776

GI number: 120610776

Start: 2299976

End: 2301637

Strand: Reverse

Name: ychM [H]

Synonym: Aave_2099

Alternate gene names: 120610776

Gene position: 2301637-2299976 (Counterclockwise)

Preceding gene: 120610777

Following gene: 120610775

Centisome position: 43.0

GC content: 72.38

Gene sequence:

>1662_bases
ATGACCACCGCAGACCTCCGAGCGGCGCGCGCCGCCGCAACCTCCCCTTCTCCCGCGACCCACGCACCGCGCGGCCTGTT
CGCCCACGTGCGGCAGGACGCGCCAGCGAGCATCGTCGTCTTCCTCGTGGCCCTGCCGCTGTGCCTGGGCATCGCGCTCG
CCAGCGGGGTTCCCCTCATGGCCGGGCTCGTGTCCGGCATCGTGGGCGGCCTCGTCGTCGGTGCGCTCTCGGGCTCCCAC
CTGAGCGTCAGCGGTCCCGCCGCCGGGCTGGTGGTGATCGTCGTGGGCTCCATCGCCAGCCTCGGCAGCTATCCGGCCTT
CCTCACCGCCGTCGTGCTGGCGGGGGCGCTGCAATGGCTGCTCGGCCGGCTGCGCGCCGGCAAGATCGGCGCCTGCTTTC
CCGCCGCCGTCATCAAGGGCATGCTCGCGGCCATCGGCCTGCTGCTGATCATCAAGCAGCTTCCCATCGCCTTCGGTTTC
CAGTCCACCGACCACGCCATGCGCGCCGTGCCTTCCGCGGCGGACACGTTCGATGCCGTGCGCCATCTCTTCAGCGCCGT
CAGCGTGGGCGCCACGGTCATCGCGGCCGGCGCCCTGGCGATCCTCTTCGCGTGGGACACCGCCTTCGTCAAGCGGCTTC
CGGTGCTCGGCCGCCTTCCGGGTCCGCTGGTCGCGGTGGTCTGGGGCGTCGGCTGCCATGCCGCCGCGCTCGCCGCGCGG
CCCTCGGCCGCACTGACCGACGCCCAGCGCGTGGCCCTGCCGGACGTCCACAGCCTCGCGGGGCTCTGGGCCCAGTTCTC
CACGCCCGACTGGTCGGCGCTCGCGAACCCGCAGGTCTATACCGTCGCGCTGACCCTGGCGTTCGTCGCCAGCCTGGAGA
CGCTGCTGAGCCTGGAAGCCACCGACCGGCTCGACCCCATGAAGCGCGTGGCCCCGCCCAACCGTGAACTGCGCGCCCAG
GGCATCGGCAACATCGTCGCGGGCCTGCTCGGCGGCCTGCCGATCACCGCGGTGATCGTGCGCAGCTCCGCCAATGTGCA
GGCCGGCGCGCGCACCCGGCTGTCGGCCATCCTGCACGGCCTGCTGCTGCTCGCGAGCCTGCTGTTCCTGGCCGAGTTCC
TCGAATGGATCCCCCTCGCGGCGCTGGCCGCCGTGCTGCTGCACACCGGCTACAAGCTCGCCAAGCCCTCGCTGGTGGCG
GCCGTGTGGCGCGAAGGCTGGGGCGTGTTCATCCCGTTCGCGGTCACCGTGGGGGCCATCCTCGCCACCGACCTGCTCAT
GGGCATCCTCATCGGCCTGGCCAGCAGCATGCTGTTCGTCATCGAGTCCAACACGCGCGGCGCGCTGTCGATGGTGTCGG
ACGGCGACATGCACCTGCTGCGGCTCAACAAGGACGTCTCGTTCTTCAGCCGCGCCAGCCTGCGCGGCTATCTCTCGCGG
GTCCGGGAGGGGCAGACACTGGTGATCGACGGCTGCGACTGCCGCTTCCTGGACCGGGACATCCGCGAGACGCTGCAGGA
CTTCCTCGCGCATGCCGAAGAGCGCGGCATCCACGTGGAATGCCGCTCCCTGCCGGGCGCCACGCCGGACTCCGGTCTCG
GGGGCGCCGTGGGCATCGCCGGCCTCGCGGCGCTGCTGCGCCCCCGCGCCGCCGCGGGCTGA

Upstream 100 bases:

>100_bases
TCTATGCGCTGCGCGACGGGCGCCTGCGCCAGGTGATCGCCCTCGACGCCGACAGCCGCCACTGGGCCGAAGCGGCCTGA
CACCGCCAGGAGACTCGCCA

Downstream 100 bases:

>100_bases
GCCGCGCGGGGCACGCCGCTTCCCCCCACCCTGGTGGGGGGTGCCGGGCGGGGCGCGGGTTCGCTACACTCGCGCCTCGC
TTCACAGACCCTTGCGGCAG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTTADLRAARAAATSPSPATHAPRGLFAHVRQDAPASIVVFLVALPLCLGIALASGVPLMAGLVSGIVGGLVVGALSGSH
LSVSGPAAGLVVIVVGSIASLGSYPAFLTAVVLAGALQWLLGRLRAGKIGACFPAAVIKGMLAAIGLLLIIKQLPIAFGF
QSTDHAMRAVPSAADTFDAVRHLFSAVSVGATVIAAGALAILFAWDTAFVKRLPVLGRLPGPLVAVVWGVGCHAAALAAR
PSAALTDAQRVALPDVHSLAGLWAQFSTPDWSALANPQVYTVALTLAFVASLETLLSLEATDRLDPMKRVAPPNRELRAQ
GIGNIVAGLLGGLPITAVIVRSSANVQAGARTRLSAILHGLLLLASLLFLAEFLEWIPLAALAAVLLHTGYKLAKPSLVA
AVWREGWGVFIPFAVTVGAILATDLLMGILIGLASSMLFVIESNTRGALSMVSDGDMHLLRLNKDVSFFSRASLRGYLSR
VREGQTLVIDGCDCRFLDRDIRETLQDFLAHAEERGIHVECRSLPGATPDSGLGGAVGIAGLAALLRPRAAAG

Sequences:

>Translated_553_residues
MTTADLRAARAAATSPSPATHAPRGLFAHVRQDAPASIVVFLVALPLCLGIALASGVPLMAGLVSGIVGGLVVGALSGSH
LSVSGPAAGLVVIVVGSIASLGSYPAFLTAVVLAGALQWLLGRLRAGKIGACFPAAVIKGMLAAIGLLLIIKQLPIAFGF
QSTDHAMRAVPSAADTFDAVRHLFSAVSVGATVIAAGALAILFAWDTAFVKRLPVLGRLPGPLVAVVWGVGCHAAALAAR
PSAALTDAQRVALPDVHSLAGLWAQFSTPDWSALANPQVYTVALTLAFVASLETLLSLEATDRLDPMKRVAPPNRELRAQ
GIGNIVAGLLGGLPITAVIVRSSANVQAGARTRLSAILHGLLLLASLLFLAEFLEWIPLAALAAVLLHTGYKLAKPSLVA
AVWREGWGVFIPFAVTVGAILATDLLMGILIGLASSMLFVIESNTRGALSMVSDGDMHLLRLNKDVSFFSRASLRGYLSR
VREGQTLVIDGCDCRFLDRDIRETLQDFLAHAEERGIHVECRSLPGATPDSGLGGAVGIAGLAALLRPRAAAG
>Mature_552_residues
TTADLRAARAAATSPSPATHAPRGLFAHVRQDAPASIVVFLVALPLCLGIALASGVPLMAGLVSGIVGGLVVGALSGSHL
SVSGPAAGLVVIVVGSIASLGSYPAFLTAVVLAGALQWLLGRLRAGKIGACFPAAVIKGMLAAIGLLLIIKQLPIAFGFQ
STDHAMRAVPSAADTFDAVRHLFSAVSVGATVIAAGALAILFAWDTAFVKRLPVLGRLPGPLVAVVWGVGCHAAALAARP
SAALTDAQRVALPDVHSLAGLWAQFSTPDWSALANPQVYTVALTLAFVASLETLLSLEATDRLDPMKRVAPPNRELRAQG
IGNIVAGLLGGLPITAVIVRSSANVQAGARTRLSAILHGLLLLASLLFLAEFLEWIPLAALAAVLLHTGYKLAKPSLVAA
VWREGWGVFIPFAVTVGAILATDLLMGILIGLASSMLFVIESNTRGALSMVSDGDMHLLRLNKDVSFFSRASLRGYLSRV
REGQTLVIDGCDCRFLDRDIRETLQDFLAHAEERGIHVECRSLPGATPDSGLGGAVGIAGLAALLRPRAAAG

Specific function: Possible sulfate transporter [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206075, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206069, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206063, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081859, Length=398, Percent_Identity=32.4120603015075, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19922482, Length=500, Percent_Identity=21.8, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649801, Length=210, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24651449, Length=137, Percent_Identity=27.007299270073, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018045
- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 57053; Mature: 56922

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCC
>Mature Secondary Structure 
TTADLRAARAAATSPSPATHAPRGLFAHVRQDAPASIVVFLVALPLCLGIALASGVPLM
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
AGLVSGIVGGLVVGALSGSHLSVSGPAAGLVVIVVGSIASLGSYPAFLTAVVLAGALQWL
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGRLRAGKIGACFPAAVIKGMLAAIGLLLIIKQLPIAFGFQSTDHAMRAVPSAADTFDAV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHCCCHHHHHHHH
RHLFSAVSVGATVIAAGALAILFAWDTAFVKRLPVLGRLPGPLVAVVWGVGCHAAALAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHCC
PSAALTDAQRVALPDVHSLAGLWAQFSTPDWSALANPQVYTVALTLAFVASLETLLSLEA
CCHHHCCHHHHCCCCHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TDRLDPMKRVAPPNRELRAQGIGNIVAGLLGGLPITAVIVRSSANVQAGARTRLSAILHG
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCCCCHHHHHHHHHHH
LLLLASLLFLAEFLEWIPLAALAAVLLHTGYKLAKPSLVAAVWREGWGVFIPFAVTVGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCCCCEEEHHHHHHHHH
LATDLLMGILIGLASSMLFVIESNTRGALSMVSDGDMHLLRLNKDVSFFSRASLRGYLSR
HHHHHHHHHHHHHHHHEEEEEECCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
VREGQTLVIDGCDCRFLDRDIRETLQDFLAHAEERGIHVECRSLPGATPDSGLGGAVGIA
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHH
GLAALLRPRAAAG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]