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The map label for this gene is can [H]

Identifier: 120610777

GI number: 120610777

Start: 2301658

End: 2302323

Strand: Reverse

Name: can [H]

Synonym: Aave_2100

Alternate gene names: 120610777

Gene position: 2302323-2301658 (Counterclockwise)

Preceding gene: 120610779

Following gene: 120610776

Centisome position: 43.01

GC content: 71.47

Gene sequence:

>666_bases
ATGGACCTCACCACCCGCCTGCTGCTCCAGAACCGCGCCTGGGCCGACGAGATGACTTCACGAGACCCCGCCTTTTTCGA
GAACCTCGTGAGCGGCCAGCAACCCCGGGCCCTCTGGATCGGATGCGCCGACAGCCGCGTGCCCGCCGAACGCATCACCA
ACGCCCTGCCGGGCGAACTGTTCGTCCACCGCAGCGTCGCCAACCTCGTGCGGCCGGACGACACCAACATCATGAGCGCC
CTCCAGTACGCCATCGACGTGCTGCGCGTGCCGGCCGTCATCGTCTGCGGCCATGAAGGCTGCGGCGGCGTGCGGGCCGC
CCTCCTGCAGTCGCGCGAACGGGTGGGCGAACCCGGCGAGGGCGACTACCTCGGCCGCCACATCCGCCCGCTGCGCTCGC
TCTACCGCCGCCGCGTTCAGGAGATCGAAACGGGCGAGAGCCTCCCGGACGCCGAGCAGGACCTGTGCTCGCGCGTGGAC
CGCTTCGTCGCATTGAACGTGGCCGAGCAGGTGCACGTGCTGTCTGCCACCGCGCCGGTGCGCCAGGCCTGGGAACGGGG
CCAGCCGCTCGCCCTGCTGGGCTGGGTCTATGCGCTGCGCGACGGGCGCCTGCGCCAGGTGATCGCCCTCGACGCCGACA
GCCGCCACTGGGCCGAAGCGGCCTGA

Upstream 100 bases:

>100_bases
CATGTAAGCAACCGAAATTCCACCCACAGGAATTCCGTCTGACGGTAACCTTGAATGCTGCGCTGCAACATCCTAAAACA
CCGCCCCCAAGGAGGAAACC

Downstream 100 bases:

>100_bases
CACCGCCAGGAGACTCGCCAATGACCACCGCAGACCTCCGAGCGGCGCGCGCCGCCGCAACCTCCCCTTCTCCCGCGACC
CACGCACCGCGCGGCCTGTT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDLTTRLLLQNRAWADEMTSRDPAFFENLVSGQQPRALWIGCADSRVPAERITNALPGELFVHRSVANLVRPDDTNIMSA
LQYAIDVLRVPAVIVCGHEGCGGVRAALLQSRERVGEPGEGDYLGRHIRPLRSLYRRRVQEIETGESLPDAEQDLCSRVD
RFVALNVAEQVHVLSATAPVRQAWERGQPLALLGWVYALRDGRLRQVIALDADSRHWAEAA

Sequences:

>Translated_221_residues
MDLTTRLLLQNRAWADEMTSRDPAFFENLVSGQQPRALWIGCADSRVPAERITNALPGELFVHRSVANLVRPDDTNIMSA
LQYAIDVLRVPAVIVCGHEGCGGVRAALLQSRERVGEPGEGDYLGRHIRPLRSLYRRRVQEIETGESLPDAEQDLCSRVD
RFVALNVAEQVHVLSATAPVRQAWERGQPLALLGWVYALRDGRLRQVIALDADSRHWAEAA
>Mature_221_residues
MDLTTRLLLQNRAWADEMTSRDPAFFENLVSGQQPRALWIGCADSRVPAERITNALPGELFVHRSVANLVRPDDTNIMSA
LQYAIDVLRVPAVIVCGHEGCGGVRAALLQSRERVGEPGEGDYLGRHIRPLRSLYRRRVQEIETGESLPDAEQDLCSRVD
RFVALNVAEQVHVLSATAPVRQAWERGQPLALLGWVYALRDGRLRQVIALDADSRHWAEAA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=43.7810945273632, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1786534, Length=203, Percent_Identity=33.4975369458128, Blast_Score=91, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=202, Percent_Identity=29.7029702970297, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24653; Mature: 24653

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTTRLLLQNRAWADEMTSRDPAFFENLVSGQQPRALWIGCADSRVPAERITNALPGEL
CCHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCHHH
FVHRSVANLVRPDDTNIMSALQYAIDVLRVPAVIVCGHEGCGGVRAALLQSRERVGEPGE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
GDYLGRHIRPLRSLYRRRVQEIETGESLPDAEQDLCSRVDRFVALNVAEQVHVLSATAPV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQAWERGQPLALLGWVYALRDGRLRQVIALDADSRHWAEAA
HHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCC
>Mature Secondary Structure
MDLTTRLLLQNRAWADEMTSRDPAFFENLVSGQQPRALWIGCADSRVPAERITNALPGEL
CCHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCHHH
FVHRSVANLVRPDDTNIMSALQYAIDVLRVPAVIVCGHEGCGGVRAALLQSRERVGEPGE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCC
GDYLGRHIRPLRSLYRRRVQEIETGESLPDAEQDLCSRVDRFVALNVAEQVHVLSATAPV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQAWERGQPLALLGWVYALRDGRLRQVIALDADSRHWAEAA
HHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]