Click here to switch to the map view.

The map label for this gene is 120610775

Identifier: 120610775

GI number: 120610775

Start: 2298747

End: 2299871

Strand: Reverse

Name: 120610775

Synonym: Aave_2098

Alternate gene names: NA

Gene position: 2299871-2298747 (Counterclockwise)

Preceding gene: 120610776

Following gene: 120610774

Centisome position: 42.97

GC content: 64.62

Gene sequence:

>1125_bases
ATGCTCGACAAACTCAACGACTTCACCGCCAGCCACGGCGAATTGCGTCCGGGCCGAGGCCACATCTCCGGCGTCATCGC
GCTCTCGCTCGGCATCCTGAGCTTCCTGGGCGTGCTCGCCTTCCACTTCCCCGAATACCTCACCACGCCGCAGCTGCGCA
AGGCCTACAACGTCGATGTGCTGCGCATGGTGCTGTTCGCAGCGCTCGTGGTGGCCGGCGGGCTCTCGCTCGTCAACATC
GTGTTCAACCGCTCGCGCTGGCTCTCGTCGGCGGCCTTCCTGCTCGTGACCTCGGCCGCGCTGCTCGGCGGCCACAAGGT
GCCCGTGCACGACTTTGCGGACAACACGCCCTACATCGGCCTGGACTGGTTCATCCTCGATCTGCTGGGCAGCGCGCTGA
TCTTCATCTTCATCGAGAAGCTCTTCGCCCTGCGGCGCGACCAGCCCATCTTCCGCCCCGAGTGGCAGTGCGATTTCCAC
CATTTCATCGTGAACCACATGGTGGTGGGTTTCGTGCTGCTGGCGACCAACCTGCTGGTGCACAAGCTGTTCGGGTGGGC
CGCCAGCGACGGCATCCGCGGCTGGGTGCAGGGCCTGAACTTCTGGGTGGCGCTCTTCCTGATCATCCTGGTGGCCGACC
TCGTGCAGTACTGGACGCACCGCGCCTACCACGAGGTGCCCGTGCTCTGGCGCCTGCACGCCGTGCACCACAGCGTCAAG
AGCATGGACTGGATGGCGGGCTCGCGCCAGCACATCCTGGAACTGCTCATCACCCGCACGCTGGTACTGGCCCCCATCTA
CGTGCTGGGTTTCTCGAAGGAGGTGATCGATGCCTACATCGTCATCGTCGGCTTCCAGGCGGTGTTCAACCATGCCAACG
TGAGCGTGCGCCTCGGCCCGCTGCGCTACGTGCTCGTCACGCCCAACTTCCACCACTGGCACCACAGCCAGGACCAGGAA
GCGCTGGACCGCAACTACGCCGCGCATTTCGCCTTCCTCGACTACCTCTTCGGCACCGCGGTCCGGAGCGACCGCCTGTG
GCCCGAGAAGTACGGCGTGCTGGGCGACTACGTGCCCAACGGATTCATCCAGCAGCTGAAGTTCCCGTTCACCTGGAAAG
GCTGA

Upstream 100 bases:

>100_bases
CGCGGGGCACGCCGCTTCCCCCCACCCTGGTGGGGGGTGCCGGGCGGGGCGCGGGTTCGCTACACTCGCGCCTCGCTTCA
CAGACCCTTGCGGCAGTCCC

Downstream 100 bases:

>100_bases
TGCATTCGCTGCCACGGTTCGACGCCGTCATCATCGGTGCCGGCGCCGCCGGCCTGTTCTGTGCCGCCCAGGCCGGCCAG
CGCGGCCTGAAGGTGCTGCT

Product: sterol desaturase

Products: NA

Alternate protein names: Sterol Desaturase; Sterol Desaturase Family Protein; Sterol Desaturase-Like Protein; Transmembrane Protein; Sterol Desaturase-Related Protein; C-5 Sterol Desaturase; TRAP Dicarboxylate Transporter; Sterol Desaturase Protein; Sterol Desaturase -Like Protein; Transmembrane Fatty Acid Synthesis Protein; Fatty Acid Hydroxylase Superfamily; Sterol Desaturase-Like; Sterol Desaturate; TRAP Dicarboxylate Transporter DctM Subunit; TRAP Dicarboxylate Transporter Subunit DctM; Sterol Desaturase Transmembrane Protein

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLDKLNDFTASHGELRPGRGHISGVIALSLGILSFLGVLAFHFPEYLTTPQLRKAYNVDVLRMVLFAALVVAGGLSLVNI
VFNRSRWLSSAAFLLVTSAALLGGHKVPVHDFADNTPYIGLDWFILDLLGSALIFIFIEKLFALRRDQPIFRPEWQCDFH
HFIVNHMVVGFVLLATNLLVHKLFGWAASDGIRGWVQGLNFWVALFLIILVADLVQYWTHRAYHEVPVLWRLHAVHHSVK
SMDWMAGSRQHILELLITRTLVLAPIYVLGFSKEVIDAYIVIVGFQAVFNHANVSVRLGPLRYVLVTPNFHHWHHSQDQE
ALDRNYAAHFAFLDYLFGTAVRSDRLWPEKYGVLGDYVPNGFIQQLKFPFTWKG

Sequences:

>Translated_374_residues
MLDKLNDFTASHGELRPGRGHISGVIALSLGILSFLGVLAFHFPEYLTTPQLRKAYNVDVLRMVLFAALVVAGGLSLVNI
VFNRSRWLSSAAFLLVTSAALLGGHKVPVHDFADNTPYIGLDWFILDLLGSALIFIFIEKLFALRRDQPIFRPEWQCDFH
HFIVNHMVVGFVLLATNLLVHKLFGWAASDGIRGWVQGLNFWVALFLIILVADLVQYWTHRAYHEVPVLWRLHAVHHSVK
SMDWMAGSRQHILELLITRTLVLAPIYVLGFSKEVIDAYIVIVGFQAVFNHANVSVRLGPLRYVLVTPNFHHWHHSQDQE
ALDRNYAAHFAFLDYLFGTAVRSDRLWPEKYGVLGDYVPNGFIQQLKFPFTWKG
>Mature_374_residues
MLDKLNDFTASHGELRPGRGHISGVIALSLGILSFLGVLAFHFPEYLTTPQLRKAYNVDVLRMVLFAALVVAGGLSLVNI
VFNRSRWLSSAAFLLVTSAALLGGHKVPVHDFADNTPYIGLDWFILDLLGSALIFIFIEKLFALRRDQPIFRPEWQCDFH
HFIVNHMVVGFVLLATNLLVHKLFGWAASDGIRGWVQGLNFWVALFLIILVADLVQYWTHRAYHEVPVLWRLHAVHHSVK
SMDWMAGSRQHILELLITRTLVLAPIYVLGFSKEVIDAYIVIVGFQAVFNHANVSVRLGPLRYVLVTPNFHHWHHSQDQE
ALDRNYAAHFAFLDYLFGTAVRSDRLWPEKYGVLGDYVPNGFIQQLKFPFTWKG

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI51972212, Length=141, Percent_Identity=32.6241134751773, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42575; Mature: 42575

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA