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The map label for this gene is yiaN [H]

Identifier: 120609445

GI number: 120609445

Start: 804940

End: 806220

Strand: Reverse

Name: yiaN [H]

Synonym: Aave_0751

Alternate gene names: 120609445

Gene position: 806220-804940 (Counterclockwise)

Preceding gene: 120609446

Following gene: 120609444

Centisome position: 15.06

GC content: 68.46

Gene sequence:

>1281_bases
ATGACCATCGCCGTCTTCCTCCTCTCGCTGCTGGGCGCCATGGCGATCGGCATCCCGATCGCGTTCTCGCTGCTGCTCTG
CGGCGTGGCGCTCATGTGGCACCTCGACATGTTCGACGCGCAGATCCTCGCGCAGAACCTGATCAACGGCGCCGACAGCT
TCCCGCTGCTGGCCGTGCCCTTCTTCATGCTGGCCGGCGAGGTCATGAACACCGGCGGCCTCTCCAGGCGCATCGTCGAT
CTGGCGCTCACCCTCGTCGGCCACGTGCGCGGCGGGCTGGGCTACGTCGCCATCGTCGCGGCCTGCGTGCTCTCGGCGCT
CTCGGGCTCGGCGGTGGCCGACGCGGCCGCGCTCTCGGCCCTGCTGGTCCCGATGATGGTGGCCGCAGGCCACGACAAGG
CGCGCTCCGGCGGCCTGATCGCCGCGGCCGGCGTGATCGGCCCCATCATCCCGCCCTCCATCGGCTTCGTGATCTTCGGC
GTGGCGGCGAACCTCTCGATCAGCAAGCTCTTCCTGGCCGGCATCTTCCCCGGCATCCTCATCGCCGGGGCCCTCTGGGC
CACGTGGTGGTGGCTGGTGCGCAGGGAACACATCGTGCCGCCGCCGCGCCGCTCGCGCAAGGAGGTCTGGCTCGCATTCC
GCCAAGCCGGCTGGGCGCTGATGCTGCCGCTCATCATCCTGGTGGGCCTGCGCTTCGGCGTCTTCACGCCCACCGAGGCG
GCCGTCGTGGCGGCGGTGTATTCGCTCTTCGTCGCCGTGGTCATCTACCGCGAACTCAAGCCCTCGCAGATCTACGGCGT
CTTCGTCACCGCCGCGCGCACCACCGGCGTGGTGATGTTCCTCGTGGCCGCGGCCCTGGTGTCGGCCTGGCTGATCACCG
TGGCCGACCTGCCGGGCAAGGTCGTCACGCTGCTGGAGCCCTTCATCGGCAGCCCCATCCTGCTGATGGCGATGATCATG
CTGCTGGTGATCGTCGTCGGCACCGCCATGGACATGACGCCCACCATCCTGATCCTCACGCCCGTGCTCATGCCCGTGGT
CAAGGCCGCCGGCATCGACCCGATCTATTTCGGGGTGCTGTTCATCATCAACAACTCCATCGGCCTCGTCACGCCGCCGG
TGGGCACGGTGCTGAACGTCGTGGCCGGCGTGGCGCGCATCCGCATGGACGATGTGATCCGCGGCGTCTGGCCGTTCATG
CTGGCGGAGTTCGCGATGATGTTCCTGATGGTGGCGTTTCCTGCGCTGGTCATCTGGCCTGCGCGCCTGCTCTACGGCTG
A

Upstream 100 bases:

>100_bases
CTGGCCGAAGAGGACCGGCTGGCCACCCAGGCCGGCGCCGCGCCCGGGCCGGACGCCGCGGACACGCAGCGCCAGCCCCG
CGGATGAGGAGCCCCGCACC

Downstream 100 bases:

>100_bases
AATCGGCTCGCGAAGCCCTTCCGGAGCCGTTGCCGGAACCGGTTGGCCGCCACCCATCCGCTGGTGCAACTGCAGCGCCC
GCTCACCCGCGCCGACCTGC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTIAVFLLSLLGAMAIGIPIAFSLLLCGVALMWHLDMFDAQILAQNLINGADSFPLLAVPFFMLAGEVMNTGGLSRRIVD
LALTLVGHVRGGLGYVAIVAACVLSALSGSAVADAAALSALLVPMMVAAGHDKARSGGLIAAAGVIGPIIPPSIGFVIFG
VAANLSISKLFLAGIFPGILIAGALWATWWWLVRREHIVPPPRRSRKEVWLAFRQAGWALMLPLIILVGLRFGVFTPTEA
AVVAAVYSLFVAVVIYRELKPSQIYGVFVTAARTTGVVMFLVAAALVSAWLITVADLPGKVVTLLEPFIGSPILLMAMIM
LLVIVVGTAMDMTPTILILTPVLMPVVKAAGIDPIYFGVLFIINNSIGLVTPPVGTVLNVVAGVARIRMDDVIRGVWPFM
LAEFAMMFLMVAFPALVIWPARLLYG

Sequences:

>Translated_426_residues
MTIAVFLLSLLGAMAIGIPIAFSLLLCGVALMWHLDMFDAQILAQNLINGADSFPLLAVPFFMLAGEVMNTGGLSRRIVD
LALTLVGHVRGGLGYVAIVAACVLSALSGSAVADAAALSALLVPMMVAAGHDKARSGGLIAAAGVIGPIIPPSIGFVIFG
VAANLSISKLFLAGIFPGILIAGALWATWWWLVRREHIVPPPRRSRKEVWLAFRQAGWALMLPLIILVGLRFGVFTPTEA
AVVAAVYSLFVAVVIYRELKPSQIYGVFVTAARTTGVVMFLVAAALVSAWLITVADLPGKVVTLLEPFIGSPILLMAMIM
LLVIVVGTAMDMTPTILILTPVLMPVVKAAGIDPIYFGVLFIINNSIGLVTPPVGTVLNVVAGVARIRMDDVIRGVWPFM
LAEFAMMFLMVAFPALVIWPARLLYG
>Mature_425_residues
TIAVFLLSLLGAMAIGIPIAFSLLLCGVALMWHLDMFDAQILAQNLINGADSFPLLAVPFFMLAGEVMNTGGLSRRIVDL
ALTLVGHVRGGLGYVAIVAACVLSALSGSAVADAAALSALLVPMMVAAGHDKARSGGLIAAAGVIGPIIPPSIGFVIFGV
AANLSISKLFLAGIFPGILIAGALWATWWWLVRREHIVPPPRRSRKEVWLAFRQAGWALMLPLIILVGLRFGVFTPTEAA
VVAAVYSLFVAVVIYRELKPSQIYGVFVTAARTTGVVMFLVAAALVSAWLITVADLPGKVVTLLEPFIGSPILLMAMIML
LVIVVGTAMDMTPTILILTPVLMPVVKAAGIDPIYFGVLFIINNSIGLVTPPVGTVLNVVAGVARIRMDDVIRGVWPFML
AEFAMMFLMVAFPALVIWPARLLYG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=422, Percent_Identity=58.7677725118483, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM [H]

EC number: NA

Molecular weight: Translated: 45120; Mature: 44988

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCC
>Mature Secondary Structure 
TIAVFLLSLLGAMAIGIPIAFSLLLCGVALMWHLDMFDAQILAQNLINGADSFPLLAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FFMLAGEVMNTGGLSRRIVDLALTLVGHVRGGLGYVAIVAACVLSALSGSAVADAAALSA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LLVPMMVAAGHDKARSGGLIAAAGVIGPIIPPSIGFVIFGVAANLSISKLFLAGIFPGIL
HHHHHHHHCCCCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IAGALWATWWWLVRREHIVPPPRRSRKEVWLAFRQAGWALMLPLIILVGLRFGVFTPTEA
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
AVVAAVYSLFVAVVIYRELKPSQIYGVFVTAARTTGVVMFLVAAALVSAWLITVADLPGK
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VVTLLEPFIGSPILLMAMIMLLVIVVGTAMDMTPTILILTPVLMPVVKAAGIDPIYFGVL
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
FIINNSIGLVTPPVGTVLNVVAGVARIRMDDVIRGVWPFMLAEFAMMFLMVAFPALVIWP
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLLYG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]