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The map label for this gene is kdgR [H]

Identifier: 120609437

GI number: 120609437

Start: 794807

End: 795589

Strand: Reverse

Name: kdgR [H]

Synonym: Aave_0741

Alternate gene names: 120609437

Gene position: 795589-794807 (Counterclockwise)

Preceding gene: 120609443

Following gene: 120609436

Centisome position: 14.86

GC content: 73.44

Gene sequence:

>783_bases
ATGGACAAGGAAAGGGCGGGCATTCAATCGGTGGAAGTGGGCTTCTCGCTGCTGGAGGGCCTGACGCGCAGCCGGGGCCC
GCTGATGCTCAAGGACCTCGCCGCCGCCGCCGGCATGAGCGCCGCCAAGGCGCACCGCTACCTCGTGAGCTTCCAGCGCA
TGGGCCTCGTCGCGCAGGATCAGCGCACCGCCCGCTACGACCTGGGCCCGGCGGCCCTGAAGCTCGGACTGGCCTCCCTC
GCCCGGCTGGACCCGGTGCGGCTCGCCCGCGAGCGCCTGCCGGCCCTCATGGAAGACATCCAGCAGACGCTGGCCCTGGC
CGTCTGGGGCAACCGGGGGCCGACCATCGTCCATTGGGAGGAGTCGCACCAGTCCGTCACCGCCAACCTGCGGCTGGGCG
ACGTGATGCCGCTGCTGTCCTCCGCCACCGGCCGTTGCTTCGCCGCGCACCTGGCGCCCGACGTGACGGCCGGGCTCATC
GCCGAGGAACTGGCCGAGGCCGCCCGGCGCGGCCGCAAGGACATTCCCGCCACGCCCGAGGCCCTGCAGCCCATGCTGGA
GGAAGTGCGCCAGCGCGGCTCCGCGCGCGTGGTGGACACGCTGCTGCCGGGCATCGTGGCCTTCTGCGCGCCGGTGTTCG
ACGCGGGCGGCCACCTGGCCCTGGGCATCACCACGCTGGGCTCCATCGCCACGTTCGACCCGGAATGGGGCGGCGCCATC
GACGCGCCGCTGCGTGCCGTGGCGCGCCGGCTCTCCAGCGACCTGGGCTACGGGCAGGCATGA

Upstream 100 bases:

>100_bases
AGACCTTGTTGTCTCCGCAGCGAGCCGGTACGCTGCCTGACACAAATTACGAATGGTTAAATTGATTTAACTAAACAAAA
CTGCGGGAATTCTATTGCAG

Downstream 100 bases:

>100_bases
GCATGGCCGCTGCCTGCCGCCGCGGGGGCCGCTGATGCCGCGCCGCGTCCTGGCGGCGCTCACCGCCCTGGTGGCCGCCC
TGCATGCGCTCGTGCTGTTC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDKERAGIQSVEVGFSLLEGLTRSRGPLMLKDLAAAAGMSAAKAHRYLVSFQRMGLVAQDQRTARYDLGPAALKLGLASL
ARLDPVRLARERLPALMEDIQQTLALAVWGNRGPTIVHWEESHQSVTANLRLGDVMPLLSSATGRCFAAHLAPDVTAGLI
AEELAEAARRGRKDIPATPEALQPMLEEVRQRGSARVVDTLLPGIVAFCAPVFDAGGHLALGITTLGSIATFDPEWGGAI
DAPLRAVARRLSSDLGYGQA

Sequences:

>Translated_260_residues
MDKERAGIQSVEVGFSLLEGLTRSRGPLMLKDLAAAAGMSAAKAHRYLVSFQRMGLVAQDQRTARYDLGPAALKLGLASL
ARLDPVRLARERLPALMEDIQQTLALAVWGNRGPTIVHWEESHQSVTANLRLGDVMPLLSSATGRCFAAHLAPDVTAGLI
AEELAEAARRGRKDIPATPEALQPMLEEVRQRGSARVVDTLLPGIVAFCAPVFDAGGHLALGITTLGSIATFDPEWGGAI
DAPLRAVARRLSSDLGYGQA
>Mature_260_residues
MDKERAGIQSVEVGFSLLEGLTRSRGPLMLKDLAAAAGMSAAKAHRYLVSFQRMGLVAQDQRTARYDLGPAALKLGLASL
ARLDPVRLARERLPALMEDIQQTLALAVWGNRGPTIVHWEESHQSVTANLRLGDVMPLLSSATGRCFAAHLAPDVTAGLI
AEELAEAARRGRKDIPATPEALQPMLEEVRQRGSARVVDTLLPGIVAFCAPVFDAGGHLALGITTLGSIATFDPEWGGAI
DAPLRAVARRLSSDLGYGQA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=257, Percent_Identity=26.4591439688716, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789999, Length=261, Percent_Identity=26.0536398467433, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082359, Length=209, Percent_Identity=24.4019138755981, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27675; Mature: 27675

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKERAGIQSVEVGFSLLEGLTRSRGPLMLKDLAAAAGMSAAKAHRYLVSFQRMGLVAQD
CCCHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHCC
QRTARYDLGPAALKLGLASLARLDPVRLARERLPALMEDIQQTLALAVWGNRGPTIVHWE
CHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
ESHQSVTANLRLGDVMPLLSSATGRCFAAHLAPDVTAGLIAEELAEAARRGRKDIPATPE
CCCCCEEECCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
ALQPMLEEVRQRGSARVVDTLLPGIVAFCAPVFDAGGHLALGITTLGSIATFDPEWGGAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHCCCCCCCCCC
DAPLRAVARRLSSDLGYGQA
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKERAGIQSVEVGFSLLEGLTRSRGPLMLKDLAAAAGMSAAKAHRYLVSFQRMGLVAQD
CCCHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHCC
QRTARYDLGPAALKLGLASLARLDPVRLARERLPALMEDIQQTLALAVWGNRGPTIVHWE
CHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
ESHQSVTANLRLGDVMPLLSSATGRCFAAHLAPDVTAGLIAEELAEAARRGRKDIPATPE
CCCCCEEECCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
ALQPMLEEVRQRGSARVVDTLLPGIVAFCAPVFDAGGHLALGITTLGSIATFDPEWGGAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHCCCCCCCCCC
DAPLRAVARRLSSDLGYGQA
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]