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The map label for this gene is ychM [C]

Identifier: 120598694

GI number: 120598694

Start: 2162239

End: 2164011

Strand: Direct

Name: ychM [C]

Synonym: Sputw3181_1879

Alternate gene names: 120598694

Gene position: 2162239-2164011 (Clockwise)

Preceding gene: 120598693

Following gene: 120598696

Centisome position: 45.92

GC content: 45.74

Gene sequence:

>1773_bases
ATGGAGGTTAACCACGTGAAGTTTCCCAGTTTAGTATCCTTTATGCCCGGGTTAGCGCAGTTATTGCAATATGAGAAGCA
GTGGCTTAGGGATGATGTACGCGCTGGATTATCCGTTGCAGCAGTGGCGTTGCCAGTGGCGATTGCCTATGCCCAACTTA
CAGGGGTAAATGCCGCTGTCGGTTTATATTCCTGTGTTTTACCTATGCTAGTGTATGCATTGTTTGGCACGTCAAGGCAA
TTAATTGTCGGTCCTGATGCTGCTACCTGTGCGGTGATTGCCGCGGTTGTCACCCCACTTGCTGCTGGTGATAGCATGAA
GCATTGGCAGCTAGTCATGACGATGACCGCGATGACCGGCTTTTGGTGTCTTATCGCGAGTCGGTTTAGACTCGGTGTAT
TAGCGGACTTCCTTTCTAAACCCATCTTGATGGGACTCCTTAACGGGGTAGCCATTACTATTATTGTGGGGCAGTTCTCC
AAAATATTTGGATTTACCTTCGATGAGCGTTACTTGATTGAGCGGCTTACTGGGGCGCCCTCCTACTTATCTAAAACCCA
TTGGCCGACCCTACTGATGGGGATTGTGACATTGGCAACCTATGCGCTGATCAAGCGTTTTCGCCCCCTTTGGCCTGCCT
CAATGTGCGCAATGGCTATGGCCGCATTTTTAGTTTGGGTATTTAATCTGACCGCCTTTGATATCAATGTAGTGGGAGAG
GTGGCCGCAGGATTACCCTCGTTTTATGCCCCAGTGTTTAATCTTGGCATTGCCCGTGAATTGGTAGTACCAGCACTTAA
CTTAGCCATGGTGAGCTTTGTCAGTATGATGCTCACAGCGCGAAGTTTTGCTGCAAAAAATGGTTATGATATTGATGCAG
ATAAAGAATTTAGAGCACTTGGCATTGCCAATATTGCGTCAGCATTATCCCAAGGTTTTGCCGTGAGCGGCGCAGATTCT
CGCACTGCAGTCAATGATGCCAATGGCGGAAAGAGTCAGCTTGTCTCGATTATTGCTGCGGTATTAATCGCCTTAGTAGC
ATTGTTTTTTACCGCACCGCTGAAATATATTCCAAGTTCCGCCCTTGGGGTTGTTTTAGTCATTGCCTCAATTTCACTTA
TCGATTTAAAAGCATTATGGAATTTACGGGTCAGAGATCGCTCAGCTTTTTTACTTGCTTGTATTACGCTATTTTCAGTC
TTATTTATTGGTGTTATTCCTGGGATTACTTTGGCGGTATTACTGGGACTATTCCAGTTTTTAGCAACCGTGATGCGTCC
GACAGATCAAGTGCTTGGATTAGATGAAAAAGGGGTCATTCGGAGTATTGATGACTCGGGAAAAGCGAAACCAGTGCCTG
GCGTATTTATTTACCGTTTTAACTCACCACTGACTTACTTTAACGCGACTTATTTTAAGCGCCGTTTACTCGAGAAGTTT
GTTCGTGAACCCGAGCCCGTAGATTGCATCATTATTGATGCAGTGCCTTGTTTTACACACCTTGATCTGAGTGTCATGGC
CATGCTGGCGGATTTACATCAGTTACTGAAAAAACGAGGTGTGCGCTTAGTATTGGCCGGGCGTAAACGTCAGATGCTTG
GGTGGTTTGAACTGACGGGCATGCAAACAGGTGAAGGCGGGATTTTAGTTCGACCAGATTTATACTTAGCGCTTAAGATG
AATCAAAGTTATAAACAGGCATTGGCTGAAGGGCAAGCACCTGTTATACAAAAGCTTCCTGATGACTCAGTGTTATTACA
TAGTCACTTGTAA

Upstream 100 bases:

>100_bases
CTAATATTGATGAATTTTTTGTGACATAGGCCTTTCGCTAACAATTTAGGCATGTCTTGATATTCTTGCCTCCAAGGATG
TGCGTATCTTGGGGGTGTAT

Downstream 100 bases:

>100_bases
GCTGAGCATTACCTTGTGGTGCAGCAAAGATGAATAGCGTAGTCATGTACTGCGCTATTTTTTACTTACTCTTTGAGAAT
GGCATCTAAGGGGATAAAAC

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MEVNHVKFPSLVSFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQ
LIVGPDAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFS
KIFGFTFDERYLIERLTGAPSYLSKTHWPTLLMGIVTLATYALIKRFRPLWPASMCAMAMAAFLVWVFNLTAFDINVVGE
VAAGLPSFYAPVFNLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADS
RTAVNDANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACITLFSV
LFIGVIPGITLAVLLGLFQFLATVMRPTDQVLGLDEKGVIRSIDDSGKAKPVPGVFIYRFNSPLTYFNATYFKRRLLEKF
VREPEPVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLGWFELTGMQTGEGGILVRPDLYLALKM
NQSYKQALAEGQAPVIQKLPDDSVLLHSHL

Sequences:

>Translated_590_residues
MEVNHVKFPSLVSFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQ
LIVGPDAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFS
KIFGFTFDERYLIERLTGAPSYLSKTHWPTLLMGIVTLATYALIKRFRPLWPASMCAMAMAAFLVWVFNLTAFDINVVGE
VAAGLPSFYAPVFNLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADS
RTAVNDANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACITLFSV
LFIGVIPGITLAVLLGLFQFLATVMRPTDQVLGLDEKGVIRSIDDSGKAKPVPGVFIYRFNSPLTYFNATYFKRRLLEKF
VREPEPVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLGWFELTGMQTGEGGILVRPDLYLALKM
NQSYKQALAEGQAPVIQKLPDDSVLLHSHL
>Mature_590_residues
MEVNHVKFPSLVSFMPGLAQLLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQ
LIVGPDAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFS
KIFGFTFDERYLIERLTGAPSYLSKTHWPTLLMGIVTLATYALIKRFRPLWPASMCAMAMAAFLVWVFNLTAFDINVVGE
VAAGLPSFYAPVFNLGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADS
RTAVNDANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACITLFSV
LFIGVIPGITLAVLLGLFQFLATVMRPTDQVLGLDEKGVIRSIDDSGKAKPVPGVFIYRFNSPLTYFNATYFKRRLLEKF
VREPEPVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGVRLVLAGRKRQMLGWFELTGMQTGEGGILVRPDLYLALKM
NQSYKQALAEGQAPVIQKLPDDSVLLHSHL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=504, Percent_Identity=26.3888888888889, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI39752683, Length=504, Percent_Identity=26.3888888888889, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI262206105, Length=550, Percent_Identity=27.4545454545455, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI262206075, Length=550, Percent_Identity=27.4545454545455, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI262206069, Length=550, Percent_Identity=27.4545454545455, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI262206063, Length=550, Percent_Identity=27.4545454545455, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI94721259, Length=500, Percent_Identity=26, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI94721257, Length=500, Percent_Identity=26, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI94721255, Length=500, Percent_Identity=26, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI94721253, Length=500, Percent_Identity=26, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI269784651, Length=500, Percent_Identity=25.8, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557535, Length=503, Percent_Identity=26.0437375745527, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4505697, Length=512, Percent_Identity=26.953125, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI45827802, Length=442, Percent_Identity=26.0180995475113, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI16418413, Length=523, Percent_Identity=23.9005736137667, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI217272867, Length=523, Percent_Identity=23.9005736137667, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI100913030, Length=523, Percent_Identity=24.8565965583174, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI47131207, Length=520, Percent_Identity=25.7692307692308, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI20336272, Length=520, Percent_Identity=25.7692307692308, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI16418457, Length=519, Percent_Identity=24.0847784200385, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI301601599, Length=519, Percent_Identity=24.0847784200385, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI20336282, Length=576, Percent_Identity=22.0486111111111, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI16306483, Length=576, Percent_Identity=22.0486111111111, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI65506789, Length=414, Percent_Identity=25.8454106280193, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI301601602, Length=287, Percent_Identity=24.7386759581882, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI45827804, Length=178, Percent_Identity=27.5280898876405, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87081859, Length=434, Percent_Identity=23.5023041474654, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI86565215, Length=508, Percent_Identity=25, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=617, Percent_Identity=24.3111831442464, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17551690, Length=578, Percent_Identity=23.5294117647059, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17566848, Length=568, Percent_Identity=25.3521126760563, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17562578, Length=500, Percent_Identity=23.8, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=507, Percent_Identity=22.4852071005917, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI86564876, Length=386, Percent_Identity=21.7616580310881, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI86565209, Length=244, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86565211, Length=244, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325260, Length=574, Percent_Identity=22.6480836236934, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=471, Percent_Identity=22.7176220806794, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319771, Length=594, Percent_Identity=22.7272727272727, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21358229, Length=467, Percent_Identity=27.1948608137045, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24649801, Length=568, Percent_Identity=25.1760563380282, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI85815873, Length=466, Percent_Identity=25.9656652360515, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24666186, Length=536, Percent_Identity=23.8805970149254, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19922482, Length=427, Percent_Identity=26.6978922716628, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355087, Length=441, Percent_Identity=25.1700680272109, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24647160, Length=441, Percent_Identity=25.1700680272109, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24651449, Length=590, Percent_Identity=21.864406779661, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21358633, Length=458, Percent_Identity=22.9257641921397, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24663084, Length=441, Percent_Identity=24.9433106575964, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357695, Length=441, Percent_Identity=24.9433106575964, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 64124; Mature: 64124

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEECCCCEEECCCEEEEEECCHHHHHHHHCCCCCHHHHCCCCCEECCCCC
>Mature Secondary Structure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CEECCCCEEECCCEEEEEECCHHHHHHHHCCCCCHHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]