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The map label for this gene is iorA [H]

Identifier: 120598400

GI number: 120598400

Start: 1806120

End: 1806623

Strand: Direct

Name: iorA [H]

Synonym: Sputw3181_1583

Alternate gene names: 120598400

Gene position: 1806120-1806623 (Clockwise)

Preceding gene: 120598399

Following gene: 120598401

Centisome position: 38.36

GC content: 49.01

Gene sequence:

>504_bases
ATGGCAGAAGTATTATCAACCACTGCAATTATCAAGGAAGCCAGTACCGCCGCTTCCACCCAAACACTTTCTATTAACGG
TAAATCATTTACTTTAGATGCCGATCCTAAGATGCCAATTCTGTGGGCACTACGGGATATTTTAGGGTTAACAGGCACTA
AATATGGCTGCGGAGCAGGGCTATGTGGTGCTTGCACTGTGCATTTAGACGGCCAACCCGTTCGAGCTTGCTTAACCAGC
CTAGGGCAAGCTCAAGGTAAACAACTAACAACGATTGAAGGGCTTGATAATCAAAAGCTTAAAAATGCTTGGGCCGAACA
TAACGTGCCCCAGTGCGGCTATTGTCAGGCGGGACAATTGATGTCGGCTGCGGCGTTAGTGGCGCAGCATCCTAAACCTA
CAGAGGAACAAATCAACTCAGCCATGTCGGGTAATCTCTGCCGCTGTGGCACCTACCCACGCATTAAAGCGGCGCTGCAA
CACTATGCCAAACAGGAGGGCTAA

Upstream 100 bases:

>100_bases
ACAGCGGGGAGCGTTAGTCGCTATAACACTACCCCGCGCCGCAATTGATATTGATACCCAAGCCGATCTTGCGTCGTGGT
TGGCACTTAAGGAGTGAGTT

Downstream 100 bases:

>100_bases
TATGAGTACTTTTACTGCCGTAGAAAATTTAAGCCGCCGCGACGTGTTAAAACTGTTTGGCGCAGTAGGGGGCGGACTTG
CATTAGGGGCGAGTGGACTA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MAEVLSTTAIIKEASTAASTQTLSINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTS
LGQAQGKQLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPTEEQINSAMSGNLCRCGTYPRIKAALQ
HYAKQEG

Sequences:

>Translated_167_residues
MAEVLSTTAIIKEASTAASTQTLSINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTS
LGQAQGKQLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPTEEQINSAMSGNLCRCGTYPRIKAALQ
HYAKQEG
>Mature_166_residues
AEVLSTTAIIKEASTAASTQTLSINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTSL
GQAQGKQLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQLMSAAALVAQHPKPTEEQINSAMSGNLCRCGTYPRIKAALQH
YAKQEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=37.1794871794872, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI71773480, Length=107, Percent_Identity=32.7102803738318, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=40.4907975460123, Blast_Score=116, Evalue=8e-28,
Organism=Escherichia coli, GI1789232, Length=138, Percent_Identity=39.1304347826087, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=38.0645161290323, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=37.5, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=168, Percent_Identity=36.3095238095238, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=36.3057324840764, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=32.5, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=35, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=32.5, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=33.1210191082803, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17618; Mature: 17487

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLSTTAIIKEASTAASTQTLSINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAG
CCHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
LCGACTVHLDGQPVRACLTSLGQAQGKQLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQL
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHH
MSAAALVAQHPKPTEEQINSAMSGNLCRCGTYPRIKAALQHYAKQEG
HHHHHHHHCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLSTTAIIKEASTAASTQTLSINGKSFTLDADPKMPILWALRDILGLTGTKYGCGAG
CHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
LCGACTVHLDGQPVRACLTSLGQAQGKQLTTIEGLDNQKLKNAWAEHNVPQCGYCQAGQL
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHH
MSAAALVAQHPKPTEEQINSAMSGNLCRCGTYPRIKAALQHYAKQEG
HHHHHHHHCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]