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The map label for this gene is fruK [H]

Identifier: 119947154

GI number: 119947154

Start: 4369720

End: 4370661

Strand: Direct

Name: fruK [H]

Synonym: Ping_3552

Alternate gene names: 119947154

Gene position: 4369720-4370661 (Clockwise)

Preceding gene: 119947153

Following gene: 119947155

Centisome position: 95.84

GC content: 43.42

Gene sequence:

>942_bases
ATGAGTAAAAATCTAAAAGTGGTTACTGTCACCTTAAACCCGGCCTTAGATCTTACCGGCTCACTTGAGGCATTACAGAC
AGGGTCTGTGAATTTAATTGAAACCGGTAGTCTGCACCCTGCAGGCAAAGGTATCAATGTTGCCAAGGTACTTGCCGAAT
TGGGTGCAAAGGTCACTGTCACAGGCTTTCTCGGGACAAATAACCAAGCTTCATTTGTAGAGTTATTTGAATCGTTAAAG
ATCAATGACCAATTTATCCGTGTTCAAGGTGATACGCGCATCAATGTCAAGATCGTTGAAAAATCCGGTCAGGTGAGCGA
TCTCAACTTCCCGGGCGTGATTGTTGGAGAATCTGAATTAGCTGAATTTGAGCGAACTTTATTTAAGCTTTCAAAAACAC
ATGATGTCTTTGTTATTGCCGGAAGCCTCCCGCAGGGCGTGACACCGGAGCATTGTGCAGGCTGGATTGAAACACTGAAC
AAAGCCGGTAAAAAAGTATTTTTTGATAGCAGCAATAAAGCCTTAGCAGCCGGTGTTAATGCACATCCTTACCTGGTTAA
ACCCAATGATGAGGAACTAAGTGCTTTACTTAATCTGCCATTAAAAAATACGGATGAAATTAAGAATGCCGCACAGCAAT
TACAGCAACAGGGTTGTCATAATGTAGTCATCTCTATGGGCGAAAATGGCGTACTTTGGCTTAACCAAGCAGGCTGGCTT
AAATCAACACCACCGAAAATGGAAGTAGTGAGCACGGTTGGCGCCGGTGATACTTTAGTCGCAGGCCTTTGTTGGAGTGA
GCTAAATCAATGGGATAAATCACAAAGTTTAAGCTTTGCCACCGCATTATCGGCGCTTGCGGTTAGCCAAGTGGGTGTGG
GTGTTGAAGACATCGATCAGGTTGAAGCATTGCAAAAAAACATAAAAATAACACAAGAGTGA

Upstream 100 bases:

>100_bases
TTAAAGACCAGTTACAGGTTACCGCACAGGGTGAAGATGCCGATCAGGCACTGCTTGCCATTGGTCAAGCGATTGAGGAC
GGCCTTGGAGAAAAAATCCA

Downstream 100 bases:

>100_bases
TTAAGAAGGTTATTTAATAACCTTAGTATTTACTTTATAAATAAATTGTTCAGAGGATAAGAATATGAAATTAGCGATAG
TCACAGCATGCCCCAGCGGC

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKNLKVVTVTLNPALDLTGSLEALQTGSVNLIETGSLHPAGKGINVAKVLAELGAKVTVTGFLGTNNQASFVELFESLK
INDQFIRVQGDTRINVKIVEKSGQVSDLNFPGVIVGESELAEFERTLFKLSKTHDVFVIAGSLPQGVTPEHCAGWIETLN
KAGKKVFFDSSNKALAAGVNAHPYLVKPNDEELSALLNLPLKNTDEIKNAAQQLQQQGCHNVVISMGENGVLWLNQAGWL
KSTPPKMEVVSTVGAGDTLVAGLCWSELNQWDKSQSLSFATALSALAVSQVGVGVEDIDQVEALQKNIKITQE

Sequences:

>Translated_313_residues
MSKNLKVVTVTLNPALDLTGSLEALQTGSVNLIETGSLHPAGKGINVAKVLAELGAKVTVTGFLGTNNQASFVELFESLK
INDQFIRVQGDTRINVKIVEKSGQVSDLNFPGVIVGESELAEFERTLFKLSKTHDVFVIAGSLPQGVTPEHCAGWIETLN
KAGKKVFFDSSNKALAAGVNAHPYLVKPNDEELSALLNLPLKNTDEIKNAAQQLQQQGCHNVVISMGENGVLWLNQAGWL
KSTPPKMEVVSTVGAGDTLVAGLCWSELNQWDKSQSLSFATALSALAVSQVGVGVEDIDQVEALQKNIKITQE
>Mature_312_residues
SKNLKVVTVTLNPALDLTGSLEALQTGSVNLIETGSLHPAGKGINVAKVLAELGAKVTVTGFLGTNNQASFVELFESLKI
NDQFIRVQGDTRINVKIVEKSGQVSDLNFPGVIVGESELAEFERTLFKLSKTHDVFVIAGSLPQGVTPEHCAGWIETLNK
AGKKVFFDSSNKALAAGVNAHPYLVKPNDEELSALLNLPLKNTDEIKNAAQQLQQQGCHNVVISMGENGVLWLNQAGWLK
STPPKMEVVSTVGAGDTLVAGLCWSELNQWDKSQSLSFATALSALAVSQVGVGVEDIDQVEALQKNIKITQE

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=310, Percent_Identity=45.1612903225806, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1788017, Length=263, Percent_Identity=32.319391634981, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788491, Length=268, Percent_Identity=26.1194029850746, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33473; Mature: 33341

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNLKVVTVTLNPALDLTGSLEALQTGSVNLIETGSLHPAGKGINVAKVLAELGAKVTV
CCCCEEEEEEEECCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCEEEE
TGFLGTNNQASFVELFESLKINDQFIRVQGDTRINVKIVEKSGQVSDLNFPGVIVGESEL
EEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEECCCCCEEEECHHHH
AEFERTLFKLSKTHDVFVIAGSLPQGVTPEHCAGWIETLNKAGKKVFFDSSNKALAAGVN
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCC
AHPYLVKPNDEELSALLNLPLKNTDEIKNAAQQLQQQGCHNVVISMGENGVLWLNQAGWL
CCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCC
KSTPPKMEVVSTVGAGDTLVAGLCWSELNQWDKSQSLSFATALSALAVSQVGVGVEDIDQ
CCCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VEALQKNIKITQE
HHHHHHCCCCCCC
>Mature Secondary Structure 
SKNLKVVTVTLNPALDLTGSLEALQTGSVNLIETGSLHPAGKGINVAKVLAELGAKVTV
CCCEEEEEEEECCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCEEEE
TGFLGTNNQASFVELFESLKINDQFIRVQGDTRINVKIVEKSGQVSDLNFPGVIVGESEL
EEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEECCCCCEEEECHHHH
AEFERTLFKLSKTHDVFVIAGSLPQGVTPEHCAGWIETLNKAGKKVFFDSSNKALAAGVN
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCC
AHPYLVKPNDEELSALLNLPLKNTDEIKNAAQQLQQQGCHNVVISMGENGVLWLNQAGWL
CCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCC
KSTPPKMEVVSTVGAGDTLVAGLCWSELNQWDKSQSLSFATALSALAVSQVGVGVEDIDQ
CCCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VEALQKNIKITQE
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]