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The map label for this gene is lpxD

Identifier: 119946587

GI number: 119946587

Start: 3657611

End: 3658633

Strand: Reverse

Name: lpxD

Synonym: Ping_2966

Alternate gene names: 119946587

Gene position: 3658633-3657611 (Counterclockwise)

Preceding gene: 119946588

Following gene: 119946586

Centisome position: 80.24

GC content: 41.45

Gene sequence:

>1023_bases
ATGGTATACAATTTAGGGCAATTAGCACAACAACTTAACGCGCAATTGGTAGGAGATGCTGAGCTCAATATATATCGACT
TGCAACCTTTGAAAAAGCCGCGCAGGGCGACATTACTTTCGTCTCTGACAAAAACTTATTAACCAGATTAGATGAATGTA
ACGCGAGTGCAATTGTATTACCGAACTCTTTTAAACAGGGCTACCAAGGTAATGCGCTGTTTATGGAGACCCCCTATGTG
GGTTATGCATTATTAGCCAGGATTTTTGATACCACGCCAAATCCGCAACCTGCTATTGCCGCCTCGGCACAGATTCATAA
AAATGCAATCATAGGTCAGAACGTGACTATTGCTCATAATGTTGTGATTGAAGAGGGTGTGGTGATTGGTGATAACTGTC
AAATTATGGACAATGTTGTTATTGGGCAGTACAGCACCTTGGGAGAAAACACCAGAATCTACCCTAATGCCACTCTTTAC
CATCAAACGGAGTTGGGTAAGCGTTGCATTATTCATGCTAATGCGGTTATCGGGTCGGATGGTTTTGGCAATGCGCCATA
TCAGGGTACCTGGATTAAAATTCCGCAAATAGGAAAAGTGATTATTGGTGATGATGTTGAAATTGGTGCTTCAACAACAA
TTGATCGTGGTGGGCTATCGGATACACTTATTGCCAATGGGGTCAAAATTGACAATCAATGTCAAATTGCCCATAACGTT
TCCATTGGTGCACATACTGCTATAGCAGGGGGGTCAAATGTTGCGGGCAGTACTAAGATAGGCTCAAACTGTATTGTAGG
CGGATGTGTTGCAATCAATGGCCATATAACCATTGTAGATAATGTTGTTGTTACGGGTGACAGCATGGTAATGCGCAGCA
TTACAGAGCCGGGTATTTATTCATCCGGTGTGCCGGCACAAAAAAATAAAGCATGGCGTAAAACAACAGCTCATACATTA
AAAATTGATGATCTATTTAAGCGTGTGAAAGCACTTGAAAAACAACTAAAAGATAATACTTAA

Upstream 100 bases:

>100_bases
GATATTATTCTTAATGGCGAGCAAATTGTTTTTTCTAAACCAGCACTTGATATATCCGAGCGTGTTATTAAAGAAATCAG
CAAAAAGTAGGTTATTAAGT

Downstream 100 bases:

>100_bases
GGAATAAAAAATCGTGACCAACGAATTAAATTCACTAGACATCAAAGAGATCATGGATCTTTTACCGCATCGTTACCCCT
TTTTACTGGTCGATCGCGTG

Product: UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MVYNLGQLAQQLNAQLVGDAELNIYRLATFEKAAQGDITFVSDKNLLTRLDECNASAIVLPNSFKQGYQGNALFMETPYV
GYALLARIFDTTPNPQPAIAASAQIHKNAIIGQNVTIAHNVVIEEGVVIGDNCQIMDNVVIGQYSTLGENTRIYPNATLY
HQTELGKRCIIHANAVIGSDGFGNAPYQGTWIKIPQIGKVIIGDDVEIGASTTIDRGGLSDTLIANGVKIDNQCQIAHNV
SIGAHTAIAGGSNVAGSTKIGSNCIVGGCVAINGHITIVDNVVVTGDSMVMRSITEPGIYSSGVPAQKNKAWRKTTAHTL
KIDDLFKRVKALEKQLKDNT

Sequences:

>Translated_340_residues
MVYNLGQLAQQLNAQLVGDAELNIYRLATFEKAAQGDITFVSDKNLLTRLDECNASAIVLPNSFKQGYQGNALFMETPYV
GYALLARIFDTTPNPQPAIAASAQIHKNAIIGQNVTIAHNVVIEEGVVIGDNCQIMDNVVIGQYSTLGENTRIYPNATLY
HQTELGKRCIIHANAVIGSDGFGNAPYQGTWIKIPQIGKVIIGDDVEIGASTTIDRGGLSDTLIANGVKIDNQCQIAHNV
SIGAHTAIAGGSNVAGSTKIGSNCIVGGCVAINGHITIVDNVVVTGDSMVMRSITEPGIYSSGVPAQKNKAWRKTTAHTL
KIDDLFKRVKALEKQLKDNT
>Mature_340_residues
MVYNLGQLAQQLNAQLVGDAELNIYRLATFEKAAQGDITFVSDKNLLTRLDECNASAIVLPNSFKQGYQGNALFMETPYV
GYALLARIFDTTPNPQPAIAASAQIHKNAIIGQNVTIAHNVVIEEGVVIGDNCQIMDNVVIGQYSTLGENTRIYPNATLY
HQTELGKRCIIHANAVIGSDGFGNAPYQGTWIKIPQIGKVIIGDDVEIGASTTIDRGGLSDTLIANGVKIDNQCQIAHNV
SIGAHTAIAGGSNVAGSTKIGSNCIVGGCVAINGHITIVDNVVVTGDSMVMRSITEPGIYSSGVPAQKNKAWRKTTAHTL
KIDDLFKRVKALEKQLKDNT

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily

Homologues:

Organism=Escherichia coli, GI1786376, Length=332, Percent_Identity=51.8072289156626, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXD_PSYIN (A1SYV3)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944267.1
- ProteinModelPortal:   A1SYV3
- SMR:   A1SYV3
- STRING:   A1SYV3
- GeneID:   4624770
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2966
- eggNOG:   COG1044
- HOGENOM:   HBG469615
- OMA:   CFVGKNT
- PhylomeDB:   A1SYV3
- BioCyc:   PING357804:PING_2966-MONOMER
- HAMAP:   MF_00523
- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573
- TIGRFAMs:   TIGR01853

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD; SSF51161 Trimer_LpxA_like

EC number: 2.3.1.-

Molecular weight: Translated: 36275; Mature: 36275

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYNLGQLAQQLNAQLVGDAELNIYRLATFEKAAQGDITFVSDKNLLTRLDECNASAIVL
CEECHHHHHHHHCCEEECCCCCEEEEEEEHHHHCCCCEEEEECCHHHHHHHHCCCCEEEE
PNSFKQGYQGNALFMETPYVGYALLARIFDTTPNPQPAIAASAQIHKNAIIGQNVTIAHN
CCHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECHHHHCCEEECCCEEEEEE
VVIEEGVVIGDNCQIMDNVVIGQYSTLGENTRIYPNATLYHQTELGKRCIIHANAVIGSD
EEEECCEEECCCCEEECCEEEECCCCCCCCCEECCCCEEEEECCCCCEEEEEEEEEECCC
GFGNAPYQGTWIKIPQIGKVIIGDDVEIGASTTIDRGGLSDTLIANGVKIDNQCQIAHNV
CCCCCCCCCEEEECCCCCEEEECCCCEECCCCEECCCCCCCHHEECCEEECCEEEEEEEC
SIGAHTAIAGGSNVAGSTKIGSNCIVGGCVAINGHITIVDNVVVTGDSMVMRSITEPGIY
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCEEEEEEEEEEECCHHHHHHCCCCCCC
SSGVPAQKNKAWRKTTAHTLKIDDLFKRVKALEKQLKDNT
CCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVYNLGQLAQQLNAQLVGDAELNIYRLATFEKAAQGDITFVSDKNLLTRLDECNASAIVL
CEECHHHHHHHHCCEEECCCCCEEEEEEEHHHHCCCCEEEEECCHHHHHHHHCCCCEEEE
PNSFKQGYQGNALFMETPYVGYALLARIFDTTPNPQPAIAASAQIHKNAIIGQNVTIAHN
CCHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECHHHHCCEEECCCEEEEEE
VVIEEGVVIGDNCQIMDNVVIGQYSTLGENTRIYPNATLYHQTELGKRCIIHANAVIGSD
EEEECCEEECCCCEEECCEEEECCCCCCCCCEECCCCEEEEECCCCCEEEEEEEEEECCC
GFGNAPYQGTWIKIPQIGKVIIGDDVEIGASTTIDRGGLSDTLIANGVKIDNQCQIAHNV
CCCCCCCCCEEEECCCCCEEEECCCCEECCCCEECCCCCCCHHEECCEEECCEEEEEEEC
SIGAHTAIAGGSNVAGSTKIGSNCIVGGCVAINGHITIVDNVVVTGDSMVMRSITEPGIY
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCEEEEEEEEEEECCHHHHHHCCCCCCC
SSGVPAQKNKAWRKTTAHTLKIDDLFKRVKALEKQLKDNT
CCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA