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The map label for this gene is fabZ

Identifier: 119946586

GI number: 119946586

Start: 3657145

End: 3657597

Strand: Reverse

Name: fabZ

Synonym: Ping_2965

Alternate gene names: 119946586

Gene position: 3657597-3657145 (Counterclockwise)

Preceding gene: 119946587

Following gene: 119946585

Centisome position: 80.22

GC content: 42.16

Gene sequence:

>453_bases
GTGACCAACGAATTAAATTCACTAGACATCAAAGAGATCATGGATCTTTTACCGCATCGTTACCCCTTTTTACTGGTCGA
TCGCGTGCTTGATTATGTACCCGGAAAAAGACTGCATGGTATTAAAAACATCTCTTTTAATGAACCCCAATTTACAGGGC
ACTTTCCTGATACACCCATTTATCCCGGTGTAATGATCCTTGAATCATTAGCGCAAGCAACGGGTGTGCTTGCCTTTGCA
ACCTACGGAAAACCTGCTGTCAATGAACTGTATTTTCTGGCATCAATGGATAAAGTACGCTTTAGAAGACCCGTTATACC
AGGTGATGTGTTAGATCTTGAAGTCATCTATCTTAAGGATCGCCGTGGCATGGGTAAATTTGAGTGTGTTGCAAAAGTGG
ATGGACAAGTCGCCTGTGAAGCGATGATCATGTGTGCAAGAAGAGAGATTTAA

Upstream 100 bases:

>100_bases
CGTAAAACAACAGCTCATACATTAAAAATTGATGATCTATTTAAGCGTGTGAAAGCACTTGAAAAACAACTAAAAGATAA
TACTTAAGGAATAAAAAATC

Downstream 100 bases:

>100_bases
TGACTAAAAAAATAGCAATGATTCATCCAACGGCGATTGTGCATGAAAATGCCATCATTGGAAAGGATGTAGAAATTGGA
CCTTATACAATTATTGGCGA

Product: (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTNELNSLDIKEIMDLLPHRYPFLLVDRVLDYVPGKRLHGIKNISFNEPQFTGHFPDTPIYPGVMILESLAQATGVLAFA
TYGKPAVNELYFLASMDKVRFRRPVIPGDVLDLEVIYLKDRRGMGKFECVAKVDGQVACEAMIMCARREI

Sequences:

>Translated_150_residues
MTNELNSLDIKEIMDLLPHRYPFLLVDRVLDYVPGKRLHGIKNISFNEPQFTGHFPDTPIYPGVMILESLAQATGVLAFA
TYGKPAVNELYFLASMDKVRFRRPVIPGDVLDLEVIYLKDRRGMGKFECVAKVDGQVACEAMIMCARREI
>Mature_149_residues
TNELNSLDIKEIMDLLPHRYPFLLVDRVLDYVPGKRLHGIKNISFNEPQFTGHFPDTPIYPGVMILESLAQATGVLAFAT
YGKPAVNELYFLASMDKVRFRRPVIPGDVLDLEVIYLKDRRGMGKFECVAKVDGQVACEAMIMCARREI

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=147, Percent_Identity=57.8231292517007, Blast_Score=189, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PSYIN (A1SYV2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944266.1
- ProteinModelPortal:   A1SYV2
- SMR:   A1SYV2
- STRING:   A1SYV2
- GeneID:   4623481
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2965
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   A1SYV2
- BioCyc:   PING357804:PING_2965-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17006; Mature: 16875

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNELNSLDIKEIMDLLPHRYPFLLVDRVLDYVPGKRLHGIKNISFNEPQFTGHFPDTPI
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCC
YPGVMILESLAQATGVLAFATYGKPAVNELYFLASMDKVRFRRPVIPGDVLDLEVIYLKD
CCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEC
RRGMGKFECVAKVDGQVACEAMIMCARREI
CCCCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNELNSLDIKEIMDLLPHRYPFLLVDRVLDYVPGKRLHGIKNISFNEPQFTGHFPDTPI
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCC
YPGVMILESLAQATGVLAFATYGKPAVNELYFLASMDKVRFRRPVIPGDVLDLEVIYLKD
CCHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEC
RRGMGKFECVAKVDGQVACEAMIMCARREI
CCCCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA