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The map label for this gene is kdsC [H]

Identifier: 119946511

GI number: 119946511

Start: 3567327

End: 3567875

Strand: Direct

Name: kdsC [H]

Synonym: Ping_2888

Alternate gene names: 119946511

Gene position: 3567327-3567875 (Clockwise)

Preceding gene: 119946503

Following gene: 119946512

Centisome position: 78.24

GC content: 40.98

Gene sequence:

>549_bases
ATGATCACAACACCTTATGGTAAAATTAGCGTCGAAAATTACCACCGCGCCGCAAAGATAAAATTACTTATTTGCGATGT
TGATGGTGTCTTTTCTGATGGTAGAATTTATTTAGGCAATCACGGCGAAGAGTTAAAAGCCTTTCATACTAAAGACGGAT
TCGGGATCAAAGCTATTATCAAGATGGGCGTTAATGTCGCGATTATCACCGGCCGTCAATCGGTCATTGTTGAAAAGAGA
ATGCAGGCCTTGGGTGTCCCTTTTATATTTCAGGGCAAAGAAGATAAATTAAGCATTTACCAATCTTTATTAACCAAGCT
TAGTTTAACGCCTGATCAGGTTGCTTATATTGGTGATGACGTGGTTGATCTGCCTATTATCGAAGATTGTGGTTTGGGTG
TCGCAGTACAGGATGCGCATCCTCTTGTCTTAAAAGGGGCAAACCTTGTCACCCAAATAAAAGGGGGCTATGGCGCAGTA
CGCGAAGTCTGTGATCTTTTTTTGCAGTGCCATAACCAACTATATATTACCCAAGGCAAAAGTGAATAA

Upstream 100 bases:

>100_bases
GTTAACGCATCCATTTTGTTATTTTATTATTTTTTTACTAACTTGTCAGTCATCACTAACTTATTAGTAACACATAATTA
TTAATCAACTGAGAATTTTA

Downstream 100 bases:

>100_bases
ATGAATAAGCGCCAGAGTATCCCATTTGTTTTATTATTAGCCGCTTTATTGATTTGGTTATTTTTCAAACAGGAAGCTGT
TTTACCTTCGTTGTCAGTCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MITTPYGKISVENYHRAAKIKLLICDVDGVFSDGRIYLGNHGEELKAFHTKDGFGIKAIIKMGVNVAIITGRQSVIVEKR
MQALGVPFIFQGKEDKLSIYQSLLTKLSLTPDQVAYIGDDVVDLPIIEDCGLGVAVQDAHPLVLKGANLVTQIKGGYGAV
REVCDLFLQCHNQLYITQGKSE

Sequences:

>Translated_182_residues
MITTPYGKISVENYHRAAKIKLLICDVDGVFSDGRIYLGNHGEELKAFHTKDGFGIKAIIKMGVNVAIITGRQSVIVEKR
MQALGVPFIFQGKEDKLSIYQSLLTKLSLTPDQVAYIGDDVVDLPIIEDCGLGVAVQDAHPLVLKGANLVTQIKGGYGAV
REVCDLFLQCHNQLYITQGKSE
>Mature_182_residues
MITTPYGKISVENYHRAAKIKLLICDVDGVFSDGRIYLGNHGEELKAFHTKDGFGIKAIIKMGVNVAIITGRQSVIVEKR
MQALGVPFIFQGKEDKLSIYQSLLTKLSLTPDQVAYIGDDVVDLPIIEDCGLGVAVQDAHPLVLKGANLVTQIKGGYGAV
REVCDLFLQCHNQLYITQGKSE

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=159, Percent_Identity=28.9308176100629, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI2367202, Length=180, Percent_Identity=50.5555555555556, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19905; Mature: 19905

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTPYGKISVENYHRAAKIKLLICDVDGVFSDGRIYLGNHGEELKAFHTKDGFGIKAII
CCCCCCCCEECCCCCCEEEEEEEEEECCCCCCCCEEEECCCCCHHEEEECCCCCCHHHHH
KMGVNVAIITGRQSVIVEKRMQALGVPFIFQGKEDKLSIYQSLLTKLSLTPDQVAYIGDD
HCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCC
VVDLPIIEDCGLGVAVQDAHPLVLKGANLVTQIKGGYGAVREVCDLFLQCHNQLYITQGK
EEECCEECCCCCCEEECCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEECC
SE
CC
>Mature Secondary Structure
MITTPYGKISVENYHRAAKIKLLICDVDGVFSDGRIYLGNHGEELKAFHTKDGFGIKAII
CCCCCCCCEECCCCCCEEEEEEEEEECCCCCCCCEEEECCCCCHHEEEECCCCCCHHHHH
KMGVNVAIITGRQSVIVEKRMQALGVPFIFQGKEDKLSIYQSLLTKLSLTPDQVAYIGDD
HCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCC
VVDLPIIEDCGLGVAVQDAHPLVLKGANLVTQIKGGYGAVREVCDLFLQCHNQLYITQGK
EEECCEECCCCCCEEECCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEECC
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]