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The map label for this gene is sapC [H]

Identifier: 119945854

GI number: 119945854

Start: 2669637

End: 2670527

Strand: Direct

Name: sapC [H]

Synonym: Ping_2194

Alternate gene names: 119945854

Gene position: 2669637-2670527 (Clockwise)

Preceding gene: 119945853

Following gene: 119945855

Centisome position: 58.55

GC content: 39.62

Gene sequence:

>891_bases
ATGCTGATAAATAACGAATTTAACGAGCAAAAAATACAATCCCCATTGCATTATATTTGGTCTATTTTCCTCAAAAACAA
TTTCGCGGTTTTTGCCATGTGGGTCGGTATTGTGCTTATCCTGATTTGCTTATTTGCTGATGTTATTGTGCTTTACTCCC
CTTTTTCACAAGATCCAGAGCACTTATTATCAGCTCCTTATTGGGTTGAAGGTGGGACGACTGAGCATCTGTTTGGCACC
GATGATTTAGGAAGGGATACGCTAGCGCGTTTAATTAAAGGTTTTCAATTCACCTTCGGTGGCGCATTACTTATCACCTG
TGCAATCACTTTTATTGGTGCCATTATCGGCTCTACAGCGGCCTTAACCAAAGGTCTTAAAGCAAGTGTTTTACATCATC
TTTTAGATGCACTTTTAACTATTCCGACATTACTTATCGCGTTTATTTTAATTGTGTTGTTCGACCCAAGTTATCAAAAC
GCCTTAATAGCAGTCTCCCTTTCACTCTTACCACAGTTTATACGGGGTATCTACAACACCATCGACAGCCAATTGAACAA
ACAATATGTCGTTGCCCTTCAACTTGATGGGGCAACCAATATACGCCTACTGCGGTTTGGTATATATCCAAATATCCTAG
AGCCAATAGTAACGCTGATCAATAGGATTTTCACTATGGCGATATTAGAAATAGCAACGCTAGGTTTCTTAGGGTTTGGC
ACCCAATCACCTGACATTGAGTTGGGTAAGCTAATCGCCGACAGCATTGATCTTTCTTATTTATCCCCCTGGCTTATTAT
ACTGCCAGGTCTGCTGATTTTTATTATCATCATGGTTGTTAATATATTTACGGAAGGTTTACGTCATGCAATTATACAAG
GGGAAGATTGA

Upstream 100 bases:

>100_bases
TCTGCAGCTGTTATCCTTATTTCAGGATTTATTTTATTATCGAGCATAGTCATCGATATTTTACAGATGGTTATTTCCCC
CACAACACGGAAAATGTTAT

Downstream 100 bases:

>100_bases
TGGCTTTATTAGATATACGCAACTTAAGCATCGATATCACAACAGCCCAGGGCACTACGCGGGTTGTTGATAAAGTATCA
TTACATATTGTTGATGGTTC

Product: peptide ABC transporter, protein inner membrane binding component SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MLINNEFNEQKIQSPLHYIWSIFLKNNFAVFAMWVGIVLILICLFADVIVLYSPFSQDPEHLLSAPYWVEGGTTEHLFGT
DDLGRDTLARLIKGFQFTFGGALLITCAITFIGAIIGSTAALTKGLKASVLHHLLDALLTIPTLLIAFILIVLFDPSYQN
ALIAVSLSLLPQFIRGIYNTIDSQLNKQYVVALQLDGATNIRLLRFGIYPNILEPIVTLINRIFTMAILEIATLGFLGFG
TQSPDIELGKLIADSIDLSYLSPWLIILPGLLIFIIIMVVNIFTEGLRHAIIQGED

Sequences:

>Translated_296_residues
MLINNEFNEQKIQSPLHYIWSIFLKNNFAVFAMWVGIVLILICLFADVIVLYSPFSQDPEHLLSAPYWVEGGTTEHLFGT
DDLGRDTLARLIKGFQFTFGGALLITCAITFIGAIIGSTAALTKGLKASVLHHLLDALLTIPTLLIAFILIVLFDPSYQN
ALIAVSLSLLPQFIRGIYNTIDSQLNKQYVVALQLDGATNIRLLRFGIYPNILEPIVTLINRIFTMAILEIATLGFLGFG
TQSPDIELGKLIADSIDLSYLSPWLIILPGLLIFIIIMVVNIFTEGLRHAIIQGED
>Mature_296_residues
MLINNEFNEQKIQSPLHYIWSIFLKNNFAVFAMWVGIVLILICLFADVIVLYSPFSQDPEHLLSAPYWVEGGTTEHLFGT
DDLGRDTLARLIKGFQFTFGGALLITCAITFIGAIIGSTAALTKGLKASVLHHLLDALLTIPTLLIAFILIVLFDPSYQN
ALIAVSLSLLPQFIRGIYNTIDSQLNKQYVVALQLDGATNIRLLRFGIYPNILEPIVTLINRIFTMAILEIATLGFLGFG
TQSPDIELGKLIADSIDLSYLSPWLIILPGLLIFIIIMVVNIFTEGLRHAIIQGED

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=297, Percent_Identity=39.3939393939394, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1789964, Length=278, Percent_Identity=34.1726618705036, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=25.3521126760563, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787760, Length=252, Percent_Identity=26.984126984127, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=26.890756302521, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787498, Length=289, Percent_Identity=26.643598615917, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32790; Mature: 32790

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINNEFNEQKIQSPLHYIWSIFLKNNFAVFAMWVGIVLILICLFADVIVLYSPFSQDPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
HLLSAPYWVEGGTTEHLFGTDDLGRDTLARLIKGFQFTFGGALLITCAITFIGAIIGSTA
HHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTKGLKASVLHHLLDALLTIPTLLIAFILIVLFDPSYQNALIAVSLSLLPQFIRGIYNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDSQLNKQYVVALQLDGATNIRLLRFGIYPNILEPIVTLINRIFTMAILEIATLGFLGFG
HHHHCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TQSPDIELGKLIADSIDLSYLSPWLIILPGLLIFIIIMVVNIFTEGLRHAIIQGED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLINNEFNEQKIQSPLHYIWSIFLKNNFAVFAMWVGIVLILICLFADVIVLYSPFSQDPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
HLLSAPYWVEGGTTEHLFGTDDLGRDTLARLIKGFQFTFGGALLITCAITFIGAIIGSTA
HHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTKGLKASVLHHLLDALLTIPTLLIAFILIVLFDPSYQNALIAVSLSLLPQFIRGIYNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDSQLNKQYVVALQLDGATNIRLLRFGIYPNILEPIVTLINRIFTMAILEIATLGFLGFG
HHHHCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TQSPDIELGKLIADSIDLSYLSPWLIILPGLLIFIIIMVVNIFTEGLRHAIIQGED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]